SLC35A2 Gene

HGNC Family Solute carriers (SLC)
Name solute carrier family 35 (UDP-galactose transporter), member A2
Description This gene encodes a member of the nucleotide-sugar transporter family. The encoded protein is a multi-pass membrane protein. It transports UDP-galactose from the cytosol into Golgi vesicles, where it serves as a glycosyl donor for the generation of glycans. Mutations in this gene cause congenital disorder of glycosylation type IIm (CDG2M). Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nSLC35A2 encodes a Golgi‐localized UDP‐galactose transporter that supplies UDP‐galactose from the cytosol to the lumen of the Golgi apparatus, a critical step for the proper glycosylation of proteins and lipids. This transporter is essential for the synthesis of galactose‐containing glycan structures, and its proper function is necessary for a host of cellular glycosylation reactions, thereby influencing protein maturation and lipid processing."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nDefects or mutations in SLC35A2 lead to a unique congenital disorder of glycosylation (CDG) that is often characterized by variable neurological impairments, including early‐onset epileptic encephalopathy. Patients may exhibit abnormal glycosylation profiles—often detected in infancy via biomarkers like transferrin—and a spectrum of clinical features such as developmental delay, hypotonia, and brain malformations. Moreover, somatic mosaicism or de novo mutations in SLC35A2 have been identified in focal malformations of cortical development, further emphasizing its role in neurodevelopment."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "4", "end_ref": "10"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its primary transporter function, SLC35A2 appears to act in concert with other nucleotide sugar transporters and glycosyltransferases to ensure efficient and accurate glycosylation. Studies have demonstrated that SLC35A2 can form heterologous complexes with related transporters (such as the UDP-N-acetylglucosamine transporter) and associate with enzymes involved in both N‐ and O‐glycosylation pathways. Structure–function analyses, including chimeric protein experiments and mutagenesis studies, have identified critical domains and pockets within SLC35A2 that confer substrate specificity and stability, emphasizing the importance of its interactions for proper glycan assembly."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "11", "end_ref": "16"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nAlterations in the expression of SLC35A2 have also been implicated in oncogenesis. In certain malignancies, including hepatocellular carcinoma and breast invasive carcinoma, aberrant SLC35A2 expression appears to modulate glycosylation patterns that impact key signaling pathways, such as ERK activation, thereby promoting tumor progression and metastasis. These findings underscore the broader significance of SLC35A2 not only in congenital disorders but also in acquired pathologies like cancer."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "17"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Bobby G Ng, Kati J Buckingham, Kimiyo Raymond, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mosaicism of the UDP-galactose transporter SLC35A2 causes a congenital disorder of glycosylation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Hum Genet (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ajhg.2013.03.012"}], "href": "https://doi.org/10.1016/j.ajhg.2013.03.012"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23561849"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23561849"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Hirofumi Kodera, Kazuyuki Nakamura, Hitoshi Osaka, et al. "}, {"type": "b", "children": [{"type": "t", "text": "De novo mutations in SLC35A2 encoding a UDP-galactose transporter cause early-onset epileptic encephalopathy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mutat (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/humu.22446"}], "href": "https://doi.org/10.1002/humu.22446"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24115232"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24115232"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Bobby G Ng, Paulina Sosicka, Satish Agadi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "SLC35A2-CDG: Functional characterization, expanded molecular, clinical, and biochemical phenotypes of 30 unreported Individuals."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mutat (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/humu.23731"}], "href": "https://doi.org/10.1002/humu.23731"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30817854"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30817854"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Mari-Anne Vals, Angel Ashikov, Pilvi Ilves, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Clinical, neuroradiological, and biochemical features of SLC35A2-CDG patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Inherit Metab Dis (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jimd.12055"}], "href": "https://doi.org/10.1002/jimd.12055"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30746764"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30746764"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Kristen Westenfield, Kyriakie Sarafoglou, Laura C Speltz, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mosaicism of the UDP-Galactose transporter SLC35A2 in a female causing a congenital disorder of glycosylation: a case report."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Med Genet (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12881-018-0617-6"}], "href": "https://doi.org/10.1186/s12881-018-0617-6"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29907092"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29907092"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Thomas Bonduelle, Till Hartlieb, Sara Baldassari, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Frequent SLC35A2 brain mosaicism in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Acta Neuropathol Commun (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s40478-020-01085-3"}], "href": "https://doi.org/10.1186/s40478-020-01085-3"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33407896"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33407896"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Carmen Barba, Ingmar Blumcke, Melodie R Winawer, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Clinical Features, Neuropathology, and Surgical Outcome in Patients With Refractory Epilepsy and Brain Somatic Variants in the "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "SLC35A2"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " Gene."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neurology (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1212/WNL.0000000000201471"}], "href": "https://doi.org/10.1212/WNL.0000000000201471"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36307217"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36307217"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "C H Lang, Y Yang, X Y Niu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "[Clinical characteristics of SLC35A2 gene variants related congenital disorders of glycosylation typeⅡ]."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Zhonghua Er Ke Za Zhi (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3760/cma.j.cn112140-20200308-00198"}], "href": "https://doi.org/10.3760/cma.j.cn112140-20200308-00198"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32605344"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32605344"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Çiğdem Seher Kasapkara, Ahmet Cevdet Ceylan, Hamit Özyürek, et al. "}, {"type": "b", "children": [{"type": "t", "text": "SLC35A2-CDG: novel variants with two ends of the spectrum."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Pediatr Endocrinol Metab (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1515/jpem-2021-0292"}], "href": "https://doi.org/10.1515/jpem-2021-0292"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34161696"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34161696"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Soad Elziny, Peter B Crino, Melodie Winawer "}, {"type": "b", "children": [{"type": "t", "text": "SLC35A2 somatic variants in drug resistant epilepsy: FCD and MOGHE."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neurobiol Dis (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.nbd.2023.106299"}], "href": "https://doi.org/10.1016/j.nbd.2023.106299"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37739137"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37739137"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Dorota Maszczak-Seneczko, Paulina Sosicka, Beata Kaczmarek, et al. "}, {"type": "b", "children": [{"type": "t", "text": "UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M115.636670"}], "href": "https://doi.org/10.1074/jbc.M115.636670"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25944901"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25944901"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Dorota Maszczak-Seneczko, Teresa Olczak, Mariusz Olczak "}, {"type": "b", "children": [{"type": "t", "text": "Subcellular localization of UDP-GlcNAc, UDP-Gal and SLC35B4 transporters."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Acta Biochim Pol (2011)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21918738"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21918738"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Mariusz Olczak, Dorota Maszczak-Seneczko, Paulina Sosicka, et al. "}, {"type": "b", "children": [{"type": "t", "text": "UDP-Gal/UDP-GlcNAc chimeric transporter complements mutation defect in mammalian cells deficient in UDP-Gal transporter."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2013.03.098"}], "href": "https://doi.org/10.1016/j.bbrc.2013.03.098"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23583405"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23583405"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Paulina Sosicka, Piotr Jakimowicz, Teresa Olczak, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Short N-terminal region of UDP-galactose transporter (SLC35A2) is crucial for galactosylation of N-glycans."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2014.10.098"}], "href": "https://doi.org/10.1016/j.bbrc.2014.10.098"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25451267"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25451267"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Danyang Li, Somshuvra Mukhopadhyay "}, {"type": "b", "children": [{"type": "t", "text": "A three-pocket model for substrate coordination and selectivity by the nucleotide sugar transporters SLC35A1 and SLC35A2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jbc.2021.101069"}], "href": "https://doi.org/10.1016/j.jbc.2021.101069"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34384782"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34384782"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Wojciech Wiertelak, Karolina Chabowska, Bożena Szulc, et al. "}, {"type": "b", "children": [{"type": "t", "text": "SLC35A2 deficiency reduces protein levels of core 1 β-1,3-galactosyltransferase 1 (C1GalT1) and its chaperone Cosmc and affects their subcellular localization."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochim Biophys Acta Mol Cell Res (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbamcr.2023.119462"}], "href": "https://doi.org/10.1016/j.bbamcr.2023.119462"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36933771"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36933771"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Hongxia Cheng, Sikai Wang, Dongmei Gao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Nucleotide sugar transporter SLC35A2 is involved in promoting hepatocellular carcinoma metastasis by regulating cellular glycosylation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Oncol (Dordr) (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s13402-022-00749-7"}], "href": "https://doi.org/10.1007/s13402-022-00749-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36454514"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36454514"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Xiaochen Yang, Yukai Tao, Yan Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "SLC35A2 expression drives breast cancer progression via ERK pathway activation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FEBS J (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/febs.17044"}], "href": "https://doi.org/10.1111/febs.17044"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38143314"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38143314"}]}]}]}
Synonyms UGT1, UGALT, CDG2M, CDGX, UDP-GAL-TR, UGT2, UGTL, UGT
Proteins S35A2_HUMAN
NCBI Gene ID 7355
API
Download Associations
Predicted Functions View SLC35A2's ARCHS4 Predicted Functions.
Co-expressed Genes View SLC35A2's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View SLC35A2's ARCHS4 Predicted Functions.

Functional Associations

SLC35A2 has 6,209 functional associations with biological entities spanning 8 categories (molecular profile, organism, disease, phenotype or trait, chemical, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 108 datasets.

Click the + buttons to view associations for SLC35A2 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles tissues with high or low expression of SLC35A2 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles tissue samples with high or low expression of SLC35A2 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray tissue samples with high or low expression of SLC35A2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq tissue samples with high or low expression of SLC35A2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles tissues with high or low expression of SLC35A2 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
BioGPS Cell Line Gene Expression Profiles cell lines with high or low expression of SLC35A2 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
BioGPS Human Cell Type and Tissue Gene Expression Profiles cell types and tissues with high or low expression of SLC35A2 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
BioGPS Mouse Cell Type and Tissue Gene Expression Profiles cell types and tissues with high or low expression of SLC35A2 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of SLC35A2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
CCLE Cell Line Gene Expression Profiles cell lines with high or low expression of SLC35A2 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
CellMarker Gene-Cell Type Associations cell types associated with SLC35A2 gene from the CellMarker Gene-Cell Type Associations dataset.
ChEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of SLC35A2 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
ChEA Transcription Factor Targets transcription factors binding the promoter of SLC35A2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
ChEA Transcription Factor Targets 2022 transcription factors binding the promoter of SLC35A2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
ClinVar Gene-Phenotype Associations phenotypes associated with SLC35A2 gene from the curated ClinVar Gene-Phenotype Associations dataset.
ClinVar Gene-Phenotype Associations 2025 phenotypes associated with SLC35A2 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
CMAP Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of SLC35A2 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores cellular components containing SLC35A2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores 2025 cellular components containing SLC35A2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
COMPARTMENTS Experimental Protein Localization Evidence Scores cellular components containing SLC35A2 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 cellular components containing SLC35A2 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores cellular components co-occuring with SLC35A2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 cellular components co-occuring with SLC35A2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of SLC35A2 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
COSMIC Cell Line Gene Mutation Profiles cell lines with SLC35A2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
CTD Gene-Disease Associations diseases associated with SLC35A2 gene/protein from the curated CTD Gene-Disease Associations dataset.
DepMap CRISPR Gene Dependency cell lines with fitness changed by SLC35A2 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
DISEASES Curated Gene-Disease Association Evidence Scores diseases involving SLC35A2 gene from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.
DISEASES Curated Gene-Disease Association Evidence Scores 2025 diseases involving SLC35A2 gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores diseases co-occuring with SLC35A2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 diseases co-occuring with SLC35A2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
DisGeNET Gene-Disease Associations diseases associated with SLC35A2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
DisGeNET Gene-Phenotype Associations phenotypes associated with SLC35A2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at SLC35A2 gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of SLC35A2 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of SLC35A2 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
ESCAPE Omics Signatures of Genes and Proteins for Stem Cells PubMedIDs of publications reporting gene signatures containing SLC35A2 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
GDSC Cell Line Gene Expression Profiles cell lines with high or low expression of SLC35A2 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
GeneRIF Biological Term Annotations biological terms co-occuring with SLC35A2 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
GeneSigDB Published Gene Signatures PubMedIDs of publications reporting gene signatures containing SLC35A2 from the GeneSigDB Published Gene Signatures dataset.
GEO Signatures of Differentially Expressed Genes for Diseases disease perturbations changing expression of SLC35A2 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of SLC35A2 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of SLC35A2 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of SLC35A2 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations transcription factor perturbations changing expression of SLC35A2 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Viral Infections virus perturbations changing expression of SLC35A2 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
GO Biological Process Annotations 2015 biological processes involving SLC35A2 gene from the curated GO Biological Process Annotations 2015 dataset.
GO Biological Process Annotations 2023 biological processes involving SLC35A2 gene from the curated GO Biological Process Annotations 2023 dataset.
GO Biological Process Annotations 2025 biological processes involving SLC35A2 gene from the curated GO Biological Process Annotations2025 dataset.
GO Cellular Component Annotations 2015 cellular components containing SLC35A2 protein from the curated GO Cellular Component Annotations 2015 dataset.
GO Cellular Component Annotations 2023 cellular components containing SLC35A2 protein from the curated GO Cellular Component Annotations 2023 dataset.
GO Cellular Component Annotations 2025 cellular components containing SLC35A2 protein from the curated GO Cellular Component Annotations 2025 dataset.
GO Molecular Function Annotations 2015 molecular functions performed by SLC35A2 gene from the curated GO Molecular Function Annotations 2015 dataset.
GO Molecular Function Annotations 2023 molecular functions performed by SLC35A2 gene from the curated GO Molecular Function Annotations 2023 dataset.
GO Molecular Function Annotations 2025 molecular functions performed by SLC35A2 gene from the curated GO Molecular Function Annotations 2025 dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of SLC35A2 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
GTEx Tissue Gene Expression Profiles 2023 tissues with high or low expression of SLC35A2 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset.
GTEx Tissue Sample Gene Expression Profiles tissue samples with high or low expression of SLC35A2 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
GTEx Tissue-Specific Aging Signatures tissue samples with high or low expression of SLC35A2 gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles cell lines with high or low expression of SLC35A2 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
HPA Cell Line Gene Expression Profiles cell lines with high or low expression of SLC35A2 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
HPA Tissue Gene Expression Profiles tissues with high or low expression of SLC35A2 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
HPA Tissue Protein Expression Profiles tissues with high or low expression of SLC35A2 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
HPA Tissue Sample Gene Expression Profiles tissue samples with high or low expression of SLC35A2 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset.
HPO Gene-Disease Associations phenotypes associated with SLC35A2 gene by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.
Hub Proteins Protein-Protein Interactions interacting hub proteins for SLC35A2 from the curated Hub Proteins Protein-Protein Interactions dataset.
HuGE Navigator Gene-Phenotype Associations phenotypes associated with SLC35A2 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
InterPro Predicted Protein Domain Annotations protein domains predicted for SLC35A2 protein from the InterPro Predicted Protein Domain Annotations dataset.
JASPAR Predicted Human Transcription Factor Targets 2025 transcription factors regulating expression of SLC35A2 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
JASPAR Predicted Mouse Transcription Factor Targets 2025 transcription factors regulating expression of SLC35A2 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of SLC35A2 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of SLC35A2 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles cell lines with high or low expression of SLC35A2 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles cell lines with SLC35A2 gene mutations from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.
LINCS L1000 CMAP Chemical Perturbation Consensus Signatures small molecule perturbations changing expression of SLC35A2 gene from the LINCS L1000 CMAP Chemical Perturbations Consensus Signatures dataset.
LINCS L1000 CMAP CRISPR Knockout Consensus Signatures gene perturbations changing expression of SLC35A2 gene from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of SLC35A2 gene from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
LOCATE Curated Protein Localization Annotations cellular components containing SLC35A2 protein in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset.
LOCATE Predicted Protein Localization Annotations cellular components predicted to contain SLC35A2 protein from the LOCATE Predicted Protein Localization Annotations dataset.
MiRTarBase microRNA Targets microRNAs targeting SLC35A2 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of SLC35A2 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
MoTrPAC Rat Endurance Exercise Training tissue samples with high or low expression of SLC35A2 gene relative to other tissue samples from the MoTrPAC Rat Endurance Exercise Training dataset.
MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations gene perturbations changing expression of SLC35A2 gene from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles drug perturbations changing expression of SLC35A2 gene from the NIBR DRUG-seq U2OS MoA Box dataset.
OMIM Gene-Disease Associations phenotypes associated with SLC35A2 gene from the curated OMIM Gene-Disease Associations dataset.
Pathway Commons Protein-Protein Interactions interacting proteins for SLC35A2 from the Pathway Commons Protein-Protein Interactions dataset.
PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of SLC35A2 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations gene perturbations changing expression of SLC35A2 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
PFOCR Pathway Figure Associations 2023 pathways involving SLC35A2 protein from the PFOCR Pathway Figure Associations 2023 dataset.
PFOCR Pathway Figure Associations 2024 pathways involving SLC35A2 protein from the Wikipathways PFOCR 2024 dataset.
Reactome Pathways 2014 pathways involving SLC35A2 protein from the Reactome Pathways dataset.
Reactome Pathways 2024 pathways involving SLC35A2 protein from the Reactome Pathways 2024 dataset.
Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures gene perturbations changing expression of SLC35A2 gene from the Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures dataset.
Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures gene perturbations changing expression of SLC35A2 gene from the Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures dataset.
Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles cell types and tissues with high or low DNA methylation of SLC35A2 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
Roadmap Epigenomics Cell and Tissue Gene Expression Profiles cell types and tissues with high or low expression of SLC35A2 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue Gene Expression Profiles dataset.
Roadmap Epigenomics Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at SLC35A2 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
RummaGEO Drug Perturbation Signatures drug perturbations changing expression of SLC35A2 gene from the RummaGEO Drug Perturbation Signatures dataset.
RummaGEO Gene Perturbation Signatures gene perturbations changing expression of SLC35A2 gene from the RummaGEO Gene Perturbation Signatures dataset.
TargetScan Predicted Conserved microRNA Targets microRNAs regulating expression of SLC35A2 gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.
TargetScan Predicted Nonconserved microRNA Targets microRNAs regulating expression of SLC35A2 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.
TCGA Signatures of Differentially Expressed Genes for Tumors tissue samples with high or low expression of SLC35A2 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores tissues with high expression of SLC35A2 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores 2025 tissues with high expression of SLC35A2 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset.
TISSUES Experimental Tissue Protein Expression Evidence Scores tissues with high expression of SLC35A2 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.
TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 tissues with high expression of SLC35A2 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores tissues co-occuring with SLC35A2 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 tissues co-occuring with SLC35A2 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset.