{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nA review of the provided literature reveals an extensive body of work devoted to understanding the regulation of mRNA translation by RNA‐binding proteins—most notably, members of the cytoplasmic polyadenylation element binding (CPEB) family—and their associated cofactors. These studies demonstrate that CPEB proteins, through regulated polyadenylation of target mRNAs, control diverse cellular processes such as synaptic plasticity, memory formation, oocyte maturation, cell polarity, and even aspects of inflammatory and metabolic regulation."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "9"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nAdditional work in these abstracts expands this picture by detailing the roles of translational regulators in developmental transitions and cellular homeostasis. The studies describe how misregulation of mRNA translation—whether by defective polyadenylation, aberrant RNA binding activity, or altered signaling pathways—can lead to phenotypes ranging from premature cellular senescence, epithelial-to-mesenchyme transition, and impaired oocyte and follicle development to defects in synaptic function underlying neurodevelopmental and neurodegenerative conditions."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "10", "end_ref": "20"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nImportantly, while these abstracts collectively provide a rich insight into the molecular mechanisms that regulate cytoplasmic mRNA translation and its implications for cell physiology and disease, none of them address or even mention SLC66A3. In other words, although SLC66A3—a member of the solute carrier family whose function in many contexts remains to be fully elucidated—might be hypothesized to intersect with cellular regulatory networks, the present literature does not offer any evidence or discussion regarding its role. This lack of information underscores an important gap in our understanding and indicates that further research is necessary to determine whether SLC66A3 participates in, or is regulated by, the translational control processes so thoroughly characterized in these studies."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "21", "end_ref": "28"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Joyce Tay, Rebecca Hodgman, Madathia Sarkissian, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes Dev (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1101/gad.1071403"}], "href": "https://doi.org/10.1101/gad.1071403"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12815066"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12815066"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Juan M Alarcon, Rebecca Hodgman, Martin Theis, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Learn Mem (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1101/lm.72704"}], "href": "https://doi.org/10.1101/lm.72704"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15169862"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15169862"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Coleen M Atkins, Naohito Nozaki, Yasushi Shigeri, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cytoplasmic polyadenylation element binding protein-dependent protein synthesis is regulated by calcium/calmodulin-dependent protein kinase II."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurosci (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1523/JNEUROSCI.0854-04.2004"}], "href": "https://doi.org/10.1523/JNEUROSCI.0854-04.2004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15175389"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15175389"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Quiping Cao, Yi-Shuian Huang, Ming-Chung Kan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.25.24.10930-10939.2005"}], "href": "https://doi.org/10.1128/MCB.25.24.10930-10939.2005"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16314516"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16314516"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Mi-Young Jung, Lori Lorenz, Joel D Richter "}, {"type": "b", "children": [{"type": "t", "text": "Translational control by neuroguidin, a eukaryotic initiation factor 4E and CPEB binding protein."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.02470-05"}], "href": "https://doi.org/10.1128/MCB.02470-05"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16705177"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16705177"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Irina Groisman, Maria Ivshina, Veronica Marin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Control of cellular senescence by CPEB."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes Dev (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1101/gad.1438906"}], "href": "https://doi.org/10.1101/gad.1438906"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17015432"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17015432"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Waldemar J Racki, Joel D Richter "}, {"type": "b", "children": [{"type": "t", "text": "CPEB controls oocyte growth and follicle development in the mouse."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Development (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/dev.02651"}], "href": "https://doi.org/10.1242/dev.02651"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17050619"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17050619"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "N Ruth Zearfoss, Juan Marcos Alarcon, Pierre Trifilieff, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurosci (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1523/JNEUROSCI.1756-08.2008"}], "href": "https://doi.org/10.1523/JNEUROSCI.1756-08.2008"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18716208"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18716208"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Sonja Hägele, Uwe Kühn, Melanie Böning, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cytoplasmic polyadenylation-element-binding protein (CPEB)1 and 2 bind to the HIF-1alpha mRNA 3'-UTR and modulate HIF-1alpha protein expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem J (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1042/BJ20081353"}], "href": "https://doi.org/10.1042/BJ20081353"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18752464"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18752464"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Congli Cai, Keiko Tamai, Kathleen Molyneaux "}, {"type": "b", "children": [{"type": "t", "text": "KHDC1B is a novel CPEB binding partner specifically expressed in mouse oocytes and early embryos."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Biol Cell (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1091/mbc.E10-03-0255"}], "href": "https://doi.org/10.1091/mbc.E10-03-0255"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20668163"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20668163"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Rachel Groppo, Joel D Richter "}, {"type": "b", "children": [{"type": "t", "text": "CPEB control of NF-kappaB nuclear localization and interleukin-6 production mediates cellular senescence."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.05133-11"}], "href": "https://doi.org/10.1128/MCB.05133-11"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21536657"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21536657"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Ilya M Alexandrov, Maria Ivshina, Dae Young Jung, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cytoplasmic polyadenylation element binding protein deficiency stimulates PTEN and Stat3 mRNA translation and induces hepatic insulin resistance."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Genet (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pgen.1002457"}], "href": "https://doi.org/10.1371/journal.pgen.1002457"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22253608"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22253608"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Kentaro Nagaoka, Tsuyoshi Udagawa, Joel D Richter "}, {"type": "b", "children": [{"type": "t", "text": "CPEB-mediated ZO-1 mRNA localization is required for epithelial tight-junction assembly and cell polarity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ncomms1678"}], "href": "https://doi.org/10.1038/ncomms1678"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22334078"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22334078"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Tsuyoshi Udagawa, Sharon A Swanger, Koichi Takeuchi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2012.05.016"}], "href": "https://doi.org/10.1016/j.molcel.2012.05.016"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22727665"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22727665"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Tsuyoshi Udagawa, Natalie G Farny, Mira Jakovcevski, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Med (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nm.3353"}], "href": "https://doi.org/10.1038/nm.3353"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24141422"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24141422"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Maria Ivshina, Ilya M Alexandrov, Anastassiia Vertii, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CPEB regulation of TAK1 synthesis mediates cytokine production and the inflammatory immune response."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.00800-14"}], "href": "https://doi.org/10.1128/MCB.00800-14"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25452303"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25452303"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Vittorio Calderone, Javier Gallego, Gonzalo Fernandez-Miranda, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Gastroenterology (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1053/j.gastro.2015.11.038"}], "href": "https://doi.org/10.1053/j.gastro.2015.11.038"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26627607"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26627607"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Joao P Sousa Martins, Xueqing Liu, Ashwini Oke, et al. "}, {"type": "b", "children": [{"type": "t", "text": "DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Sci (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/jcs.179218"}], "href": "https://doi.org/10.1242/jcs.179218"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26826184"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26826184"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Jiao Yue, Xin-Shang Wang, Yan-Yan Guo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Anxiolytic effect of CPEB1 knockdown on the amygdala of a mouse model of inflammatory pain."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Brain Res Bull (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.brainresbull.2017.12.002"}], "href": "https://doi.org/10.1016/j.brainresbull.2017.12.002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29242136"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29242136"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Xing-Xing Dai, Jun-Chao Jiang, Qian-Qian Sha, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A combinatorial code for mRNA 3'-UTR-mediated translational control in the mouse oocyte."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nucleic Acids Res (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/nar/gky971"}], "href": "https://doi.org/10.1093/nar/gky971"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30335155"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30335155"}]}, {"type": "r", "ref": 21, "children": [{"type": "t", "text": "Xin-Shang Wang, Jiao Yue, Li-Ning Hu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Effects of CPEB1 in the anterior cingulate cortex on visceral pain in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Brain Res (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.brainres.2019.02.001"}], "href": "https://doi.org/10.1016/j.brainres.2019.02.001"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30731077"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30731077"}]}, {"type": "r", "ref": 22, "children": [{"type": "t", "text": "Fernanda Mansur, Juan Marcos Alarcon, Emily E Stackpole, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Noncanonical cytoplasmic poly(A) polymerases regulate RNA levels, alternative RNA processing, and synaptic plasticity but not hippocampal-dependent behaviours."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "RNA Biol (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/15476286.2020.1824061"}], "href": "https://doi.org/10.1080/15476286.2020.1824061"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32954964"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32954964"}]}, {"type": "r", "ref": 23, "children": [{"type": "t", "text": "Souichi Oe, Taro Koike, Yukie Hirahara, et al. "}, {"type": "b", "children": [{"type": "t", "text": "AUF1, an mRNA decay factor, has a discordant role in Cpeb1 expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2020.11.054"}], "href": "https://doi.org/10.1016/j.bbrc.2020.11.054"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33220927"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33220927"}]}, {"type": "r", "ref": 24, "children": [{"type": "t", "text": "Gelei Xiao, Qianwei Chen, Xuewei Zhang "}, {"type": "b", "children": [{"type": "t", "text": "MicroRNA-455-5p/CPEB1 pathway mediates Aβ-related learning and memory deficits in a mouse model of Alzheimer's disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Brain Res Bull (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.brainresbull.2021.10.008"}], "href": "https://doi.org/10.1016/j.brainresbull.2021.10.008"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34678444"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34678444"}]}, {"type": "r", "ref": 25, "children": [{"type": "t", "text": "Qianxing Hu, Jinming Mu, Yuhong Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Obesity-Induced miR-455 Upregulation Promotes Adaptive Pancreatic β-Cell Proliferation Through the CPEB1/CDKN1B Pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Diabetes (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2337/db21-0134"}], "href": "https://doi.org/10.2337/db21-0134"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35029277"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35029277"}]}, {"type": "r", "ref": 26, "children": [{"type": "t", "text": "Maria P Ivshina, Heleen M van 't Spijker, Suna Jung, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CPEB1 regulates the inflammatory immune response, phagocytosis, and alternative polyadenylation in microglia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Glia (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/glia.24222"}], "href": "https://doi.org/10.1002/glia.24222"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35635122"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35635122"}]}, {"type": "r", "ref": 27, "children": [{"type": "t", "text": "Zhihua Zhang, Ruyi Liu, Hongbin Zhou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PATL2 regulates mRNA homeostasis in oocytes by interacting with EIF4E and CPEB1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Development (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/dev.201572"}], "href": "https://doi.org/10.1242/dev.201572"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37218508"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37218508"}]}, {"type": "r", "ref": 28, "children": [{"type": "t", "text": "Chisato Kunitomi, Mayra Romero, Enrico Maria Daldello, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Multiple intersecting pathways are involved in CPEB1 phosphorylation and regulation of translation during mouse oocyte meiosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Development (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/dev.202712"}], "href": "https://doi.org/10.1242/dev.202712"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38785133"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38785133"}]}]}]}