SMARCC1 Gene

HGNC Family	SANT/Myb domain containing
Name	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
Description	The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nSMARCC1, also known as BAF155 or SRG3, serves as a pivotal scaffold subunit within the evolutionarily conserved SWI/SNF chromatin remodeling complex. It orchestrates the proper assembly and stoichiometric balance of the complex by mediating critical protein–protein interactions and by protecting associated subunits from proteasomal degradation. In addition, post‐translational modifications—such as Akt‐dependent phosphorylation—further modulate its function. Detailed structural analyses have revealed that its SWIRM domain forms specific binding interfaces with core subunits (for example, engaging with BAF47 and SNF5), and its modular architecture may even present novel targets for small molecule intervention."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "9"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn the cancer arena, aberrations in SMARCC1 expression and function have been linked to tumorigenesis and disease progression. For instance, upregulation of SMARCC1 has been associated with prostate cancer progression, whereas in colorectal cancer higher SMARCC1 protein levels correlate with improved overall survival. In other tumor types, loss or mutation of SMARCC1 confers tumor‐suppressive effects, as re‐expression of the full‐length protein can induce replicative senescence and reduce colony formation. Moreover, post‐translational events—such as methylation events affecting associated subunits—and interactions with transcription factors like NKX6.1 and MYC help modulate oncogenic transcriptional programs and the epithelial–mesenchymal transition, thereby influencing cancer cell migration and metastasis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "10", "end_ref": "16"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its oncogenic roles, SMARCC1 is crucial for normal development and broader cellular homeostasis. Rare loss‐of‐function variants in SMARCC1 have been linked to congenital hydrocephalus, ventriculomegaly, and complex developmental dysgenesis syndromes—findings that underscore its indispensable role in neurodevelopment. In addition, SMARCC1 influences cellular metabolism by regulating respiration through chromatin‐mediated mechanisms, and its expression is tightly controlled via ubiquitin–proteasome pathways (for example, through the action of nuclear E3 ligases) to fine‐tune inflammatory gene expression. These multifaceted roles highlight SMARCC1 as a master regulator spanning chromatin remodeling, transcriptional control, metabolic regulation, and developmental morphogenesis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "17", "end_ref": "22"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Jianguang Chen, Trevor K Archer "}, {"type": "b", "children": [{"type": "t", "text": "Regulating SWI/SNF subunit levels via protein-protein interactions and proteasomal degradation: BAF155 and BAF170 limit expression of BAF57."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.25.20.9016-9027.2005"}], "href": "https://doi.org/10.1128/MCB.25.20.9016-9027.2005"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16199878"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16199878"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "K S J Foster, W J McCrary, J S Ross, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Members of the hSWI/SNF chromatin remodeling complex associate with and are phosphorylated by protein kinase B/Akt."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncogene (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.onc.1209496"}], "href": "https://doi.org/10.1038/sj.onc.1209496"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16568092"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16568092"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Brian R Keppler, Trevor K Archer "}, {"type": "b", "children": [{"type": "t", "text": "Ubiquitin-dependent and ubiquitin-independent control of subunit stoichiometry in the SWI/SNF complex."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M110.173997"}], "href": "https://doi.org/10.1074/jbc.M110.173997"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20829358"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20829358"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Sunjin Moon, Joon Shin, Dongju Lee, et al. "}, {"type": "b", "children": [{"type": "t", "text": "1H, 15N, and 13C resonance assignments and secondary structure of the SWIRM domain of human BAF155, a chromatin remodeling complex component."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cells (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10059-013-0119-5"}], "href": "https://doi.org/10.1007/s10059-013-0119-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23996527"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23996527"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Li Yan, Si Xie, Yongming Du, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Structural Insights into BAF47 and BAF155 Complex Formation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Mol Biol (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jmb.2017.04.008"}], "href": "https://doi.org/10.1016/j.jmb.2017.04.008"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28438634"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28438634"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Huijing Chen, Yi Zhang, Shuangshuang Ye, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Chromatin remodelling factor BAF155 protects hepatitis B virus X protein (HBx) from ubiquitin-independent proteasomal degradation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Emerg Microbes Infect (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/22221751.2019.1666661"}], "href": "https://doi.org/10.1080/22221751.2019.1666661"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31533543"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31533543"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Jeongmin Han, Iktae Kim, Jae-Hyun Park, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A Coil-to-Helix Transition Serves as a Binding Motif for hSNF5 and BAF155 Interaction."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Sci (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/ijms21072452"}], "href": "https://doi.org/10.3390/ijms21072452"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32244797"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32244797"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Mark D Allen, Stefan M V Freund, Mark Bycroft, et al. "}, {"type": "b", "children": [{"type": "t", "text": "SWI/SNF subunit BAF155 N-terminus structure informs the impact of cancer-associated mutations and reveals a potential drug binding site."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Commun Biol (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s42003-021-02050-z"}], "href": "https://doi.org/10.1038/s42003-021-02050-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33953332"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33953332"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Chunming Dong, Rui Zhang, Lijun Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Assembly and interaction of core subunits of BAF complexes and crystal study of the SMARCC1/SMARCE1 binary complex."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2022.02.007"}], "href": "https://doi.org/10.1016/j.bbrc.2022.02.007"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35158202"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35158202"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "S Heebøll, M Borre, P D Ottosen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "SMARCC1 expression is upregulated in prostate cancer and positively correlated with tumour recurrence and dedifferentiation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Histol Histopathol (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.14670/HH-23.1069"}], "href": "https://doi.org/10.14670/HH-23.1069"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18581278"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18581278"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "C L Andersen, L L Christensen, K Thorsen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Dysregulation of the transcription factors SOX4, CBFB and SMARCC1 correlates with outcome of colorectal cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Br J Cancer (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.bjc.6604884"}], "href": "https://doi.org/10.1038/sj.bjc.6604884"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19156145"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19156145"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Jessica DelBove, Gary Rosson, Matthew Strobeck, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of a core member of the SWI/SNF complex, BAF155/SMARCC1, as a human tumor suppressor gene."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Epigenetics (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4161/epi.6.12.18492"}], "href": "https://doi.org/10.4161/epi.6.12.18492"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22139574"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22139574"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Lu Wang, Zibo Zhao, Mark B Meyer, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Cell (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ccr.2013.12.007"}], "href": "https://doi.org/10.1016/j.ccr.2013.12.007"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24434208"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24434208"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "H-J Li, P-N Yu, K-Y Huang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "NKX6.1 functions as a metastatic suppressor through epigenetic regulation of the epithelial-mesenchymal transition."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncogene (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/onc.2015.289"}], "href": "https://doi.org/10.1038/onc.2015.289"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26257059"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26257059"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Shao-Bo Ke, Hu Qiu, Jia-Mei Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MicroRNA-202-5p functions as a tumor suppressor in colorectal carcinoma by directly targeting SMARCC1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Gene (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.gene.2018.08.064"}], "href": "https://doi.org/10.1016/j.gene.2018.08.064"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30144500"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30144500"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Chase M Woodley, Alexander S Romer, Jing Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncogene (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41388-021-01804-7"}], "href": "https://doi.org/10.1038/s41388-021-01804-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33931740"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33931740"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Xinlong Luo, Beibei Wang, Fan Tang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Wwp2 targets SRG3, a scaffold protein of the SWI/SNF-like BAF complex, for ubiquitination and degradation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2013.12.089"}], "href": "https://doi.org/10.1016/j.bbrc.2013.12.089"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24365151"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24365151"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Sneha Lal, Md Maksudul Alam, Jagmohan Hooda, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Swi3 protein plays a unique role in regulating respiration in eukaryotes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biosci Rep (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1042/BSR20160083"}], "href": "https://doi.org/10.1042/BSR20160083"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27190130"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27190130"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Wei Liu, Ziqiao Wang, Shuo Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Rep (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.celrep.2023.112097"}], "href": "https://doi.org/10.1016/j.celrep.2023.112097"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36800290"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36800290"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Nicolas Rive Le Gouard, Romain Nicolle, Mathilde Lefebvre, et al. "}, {"type": "b", "children": [{"type": "t", "text": "First reports of fetal SMARCC1 related hydrocephalus."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur J Med Genet (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ejmg.2023.104797"}], "href": "https://doi.org/10.1016/j.ejmg.2023.104797"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37285932"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37285932"}]}, {"type": "r", "ref": 21, "children": [{"type": "t", "text": "Ognjen Milicevic, Ana Loncar, Dzihan Abazovic, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Transcriptome from Paired Samples Improves the Power of Comprehensive COVID-19 Host-Viral Characterization."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Sci (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/ijms241713125"}], "href": "https://doi.org/10.3390/ijms241713125"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37685932"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37685932"}]}, {"type": "r", "ref": 22, "children": [{"type": "t", "text": "Amrita K Singh, Garrett Allington, Stephen Viviano, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Brain (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/brain/awad405"}], "href": "https://doi.org/10.1093/brain/awad405"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38128548"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38128548"}]}]}]}
Synonyms	BAF155, SRG3, SWI3, Rsc8, CRACC1
Proteins	SMRC1_HUMAN
NCBI Gene ID	6599
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

SMARCC1 has 8,886 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 126 datasets.

Click the + buttons to view associations for SMARCC1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

SMARCC1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by SMARCC1 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of SMARCC1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of SMARCC1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of SMARCC1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of SMARCC1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of SMARCC1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	Biocarta Pathways	pathways involving SMARCC1 protein from the Biocarta Pathways dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of SMARCC1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of SMARCC1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of SMARCC1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of SMARCC1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of SMARCC1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with SMARCC1 protein from the CCLE Cell Line Proteomics dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SMARCC1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of SMARCC1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of SMARCC1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of SMARCC1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing SMARCC1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing SMARCC1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing SMARCC1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing SMARCC1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with SMARCC1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with SMARCC1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CORUM Protein Complexes	protein complexs containing SMARCC1 protein from the CORUM Protein Complexes dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of SMARCC1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with SMARCC1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with SMARCC1 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with SMARCC1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by SMARCC1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with SMARCC1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with SMARCC1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with SMARCC1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with SMARCC1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at SMARCC1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SMARCC1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of SMARCC1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing SMARCC1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with SMARCC1 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with SMARCC1 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of SMARCC1 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.