{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe abstract (1) reports on a long noncoding RNA, LINC00634, which is upregulated in esophageal cancer tissues compared with adjacent non‐tumor tissues. The study demonstrates that LINC00634 positively influences tumor cell viability while suppressing apoptosis. This effect is mediated, at least in part, via its regulation of the miR-342-3p/Bcl2L1 axis, such that knocking down LINC00634 leads to decreased cell viability and increased apoptotic activity in esophageal cancer cells.\n"}]}, {"type": "t", "text": "\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIt is important to note that the provided abstract (1) does not mention SMIM45, and therefore no direct conclusions regarding the function of SMIM45 can be drawn from this study. If one were to consider SMIM45 in the context of cancer biology, further investigation and dedicated studies would be required to determine whether SMIM45 participates in similar regulatory networks or influences cellular proliferation and apoptosis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Xiaohong Zhang, Yinman Feng, Yanli Gao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Long Noncoding RNA LINC00634 Functions as an Oncogene in Esophageal Squamous Cell Carcinoma Through the miR-342-3p/Bcl2L1 Axis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Technol Cancer Res Treat (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1177/1533033820928508"}], "href": "https://doi.org/10.1177/1533033820928508"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32583748"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32583748"}]}]}]}