SNORD116-21 Gene

HGNC Family	Non-coding RNAs
Name	small nucleolar RNA, C/D box 116-21
Description	Predicted to be involved in RNA processing. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Mar 2025]
Synonyms	HBII-85-21
NCBI Gene ID	100033432
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

SNORD116-21 has 674 functional associations with biological entities spanning 5 categories (molecular profile, functional term, phrase or reference, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 15 datasets.

Click the + buttons to view associations for SNORD116-21 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

SNORD116-21 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of SNORD116-21 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at SNORD116-21 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SNORD116-21 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of SNORD116-21 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing SNORD116-21 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of SNORD116-21 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of SNORD116-21 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	transcription factor perturbations changing expression of SNORD116-21 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of SNORD116-21 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	GTEx Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of SNORD116-21 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of SNORD116-21 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of SNORD116-21 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	transcription factor perturbations changing expression of SNORD116-21 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
	MiRTarBase microRNA Targets	microRNAs targeting SNORD116-21 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.
	Roadmap Epigenomics Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at SNORD116-21 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.