{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nSNORD14E has emerged as a key small nucleolar RNA in colon adenocarcinoma, where its differential expression is closely associated with patient prognosis. In a study involving gene expression profiling and Cox regression analyses of colon adenocarcinoma samples, SNORD14E, alongside SNORD67, was identified as one of the few snoRNAs with significant prognostic value. Elevated levels of SNORD14E were linked to a higher risk score in prognostic models, with patients in the high-risk group exhibiting lower survival rates. These findings suggest that SNORD14E may play an important role in tumor progression and could serve as a valuable biomarker for predicting clinical outcomes and guiding personalized treatment strategies in malignant colon tumors."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Li Huang, Xu-Zhi Liang, Yun Deng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Prognostic value of small nucleolar RNAs (snoRNAs) for colon adenocarcinoma based on RNA sequencing data."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pathol Res Pract (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.prp.2020.152937"}], "href": "https://doi.org/10.1016/j.prp.2020.152937"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32312483"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32312483"}]}]}]}