SNORD30 Gene

HGNC Family Non-coding RNAs
Name small nucleolar RNA, C/D box 30
Description Predicted to be involved in RNA processing. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Mar 2025]
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nRecent transcriptomic analyses in high‐risk smoldering myeloma have identified that members of the small nucleolar RNA (snoRNA) family—including SNORD30—are significantly overexpressed in patients who progress more rapidly to symptomatic disease. In particular, the overexpression of SNORD30 together with SNORD25, SNORD27, and SNORD31 was correlated with a shorter time to progression, suggesting that SNORD30 may serve as a valuable prognostic biomarker. Such findings imply that SNORD30 might reflect or even contribute to underlying molecular mechanisms that drive malignant transformation in plasma cells, and its differential expression could be harnessed to stratify patient risk and potentially guide therapeutic interventions."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Lucía López-Corral, María Victoria Mateos, Luis A Corchete, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genomic analysis of high-risk smoldering multiple myeloma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Haematologica (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3324/haematol.2011.060780"}], "href": "https://doi.org/10.3324/haematol.2011.060780"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22331267"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22331267"}]}]}]}
Synonyms RNU30, U30
NCBI Gene ID 9299
API
Download Associations
Predicted Functions View SNORD30's ARCHS4 Predicted Functions.
Co-expressed Genes View SNORD30's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View SNORD30's ARCHS4 Predicted Functions.

Functional Associations

SNORD30 has 952 functional associations with biological entities spanning 5 categories (molecular profile, functional term, phrase or reference, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 15 datasets.

Click the + buttons to view associations for SNORD30 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of SNORD30 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
ChEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of SNORD30 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
ChEA Transcription Factor Targets transcription factors binding the promoter of SNORD30 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at SNORD30 gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of SNORD30 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of SNORD30 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
GeneSigDB Published Gene Signatures PubMedIDs of publications reporting gene signatures containing SNORD30 from the GeneSigDB Published Gene Signatures dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of SNORD30 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of SNORD30 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of SNORD30 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of SNORD30 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of SNORD30 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles cell lines with high or low expression of SNORD30 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.
KnockTF Gene Expression Profiles with Transcription Factor Perturbations transcription factor perturbations changing expression of SNORD30 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
Roadmap Epigenomics Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at SNORD30 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.