SNORD67 Gene

HGNC Family Non-coding RNAs
Name small nucleolar RNA, C/D box 67
Description Predicted to be involved in RNA processing. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Mar 2025]
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe small nucleolar RNA SNORD67 has been identified as a significant prognostic biomarker in colon adenocarcinoma. In a study analyzing gene expression profiles in colon cancer, SNORD67 emerged as one of two snoRNAs (along with SNORD14E) that were independently associated with patient outcomes. Its expression level contributed to the creation of a prognostic risk scoring model that successfully stratified patients into high-risk and low-risk groups, with the high-risk group exhibiting notably lower survival rates."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nThe findings underscore the potential clinical utility of SNORD67 in predicting disease progression and overall prognosis. By integrating SNORD67 expression data into the prognostic model, clinicians might be better equipped to tailor treatment strategies based on the molecular profile of the tumor. These results mark SNORD67 as a promising candidate for further research that may lead to improved prognostic evaluation and personalized therapeutic approaches in colon adenocarcinoma."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Li Huang, Xu-Zhi Liang, Yun Deng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Prognostic value of small nucleolar RNAs (snoRNAs) for colon adenocarcinoma based on RNA sequencing data."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pathol Res Pract (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.prp.2020.152937"}], "href": "https://doi.org/10.1016/j.prp.2020.152937"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32312483"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32312483"}]}]}]}
Synonyms HBII-166
NCBI Gene ID 692108
API
Download Associations
Predicted Functions View SNORD67's ARCHS4 Predicted Functions.
Co-expressed Genes View SNORD67's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View SNORD67's ARCHS4 Predicted Functions.

Functional Associations

SNORD67 has 385 functional associations with biological entities spanning 3 categories (molecular profile, cell line, cell type or tissue, gene, protein or microRNA) extracted from 15 datasets.

Click the + buttons to view associations for SNORD67 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of SNORD67 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
ChEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of SNORD67 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
ChEA Transcription Factor Targets transcription factors binding the promoter of SNORD67 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of SNORD67 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at SNORD67 gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of SNORD67 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of SNORD67 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of SNORD67 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of SNORD67 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of SNORD67 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles cell lines with high or low expression of SNORD67 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.
KnockTF Gene Expression Profiles with Transcription Factor Perturbations transcription factor perturbations changing expression of SNORD67 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of SNORD67 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
Roadmap Epigenomics Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at SNORD67 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
TCGA Signatures of Differentially Expressed Genes for Tumors tissue samples with high or low expression of SNORD67 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.