SPMIP5 Gene

Name sperm microtubule inner protein 5
Description Predicted to be involved in flagellated sperm motility. Predicted to be located in several cellular components, including cytoskeleton; motile cilium; and nucleus. Predicted to be active in axonemal A tubule inner sheath and sperm flagellum. [provided by Alliance of Genome Resources, Mar 2025]
NCBI Gene ID 143379
API
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Predicted Functions View SPMIP5's ARCHS4 Predicted Functions.
Co-expressed Genes View SPMIP5's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View SPMIP5's ARCHS4 Predicted Functions.

Functional Associations

SPMIP5 has 423 functional associations with biological entities spanning 5 categories (disease, phenotype or trait, chemical, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 9 datasets.

Click the + buttons to view associations for SPMIP5 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles tissue samples with high or low expression of SPMIP5 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
CM4AI KOLF21J CRISPRi Gene Perturbation Atlas gene perturbations changing expression of SPMIP5 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
GTEx eQTL 2025 SNPs regulating expression of SPMIP5 gene from the GTEx eQTL 2025 dataset.
GWAS Catalog SNP-Phenotype Associations 2025 phenotypes associated with SPMIP5 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.
JASPAR Predicted Human Transcription Factor Targets 2025 transcription factors regulating expression of SPMIP5 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
JASPAR Predicted Mouse Transcription Factor Targets 2025 transcription factors regulating expression of SPMIP5 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset.
Rummagene Transcription Factor Associations 2026 transcription factors regulating expression of SPMIP5 gene from the Rummagene Transcription Factor Associations 2026 dataset.
RummaGEO Drug Perturbation Signatures drug perturbations changing expression of SPMIP5 gene from the RummaGEO Drug Perturbation Signatures dataset.
RummaGEO Gene Perturbation Signatures gene perturbations changing expression of SPMIP5 gene from the RummaGEO Gene Perturbation Signatures dataset.