TBX19 Gene

HGNC Family	T-boxes (TBX)
Name	T-box 19
Description	This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nTBX19, also known as TPIT, is a highly cell‐restricted T‑box transcription factor that orchestrates the terminal differentiation of pituitary corticotroph and melanotroph cells by activating the transcription of the pro‐opiomelanocortin (POMC) gene. It recruits specific co‐activators (for example, SRC/p160) and cooperates with other transcription factors such as Pitx1 to mediate hormone signaling from corticotropin‑releasing hormone via cAMP‐dependent and mitogen‑activated protein kinase pathways. Disruption of TBX19 function—through various loss‑of‑function mutations—leads to isolated adrenocorticotropic hormone (ACTH) deficiency (IAD), a severe neonatal condition characterized by low plasma ACTH and cortisol levels despite preserved secretion of other pituitary hormones. This well‑characterized genetic etiology, typically inherited in an autosomal recessive pattern, underpins several congenital and early‑onset cases of ACTH deficiency and has provided unique opportunities for early diagnosis and therapeutic intervention."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "13"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nEmerging evidence further broadens the functional repertoire of TBX19. Genetic variation at the TBX19 locus has been linked with personality traits—specifically, increased angry hostility—thereby implicating this transcription factor in neurobehavioral regulation. In parallel, aberrant TBX19 expression has been observed in non‐pituitary settings: overexpression promotes hepatocellular carcinoma metastasis by upregulating key effectors such as epidermal growth factor receptor (EGFR) and RAC1, while in colorectal cancer, TBX19 mRNA levels are elevated and associated with lymph node metastasis. These observations suggest that, in addition to its established endocrine duties, TBX19 may function as an oncogenic driver and modulator of behavioral phenotypes."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "14", "end_ref": "16"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn summary, TBX19 is pivotal not only for pituitary cell differentiation and POMC gene transcription but also for maintaining normal adrenal function. Its disruption results in isolated ACTH deficiency—a condition with critical neonatal implications—while its dysregulation in other tissues underscores a broader involvement in oncogenesis and, potentially, neurobehavioral processes. These multifaceted roles make TBX19 an attractive target for both early therapeutic intervention in endocrine deficiencies and the development of novel strategies to combat TBX19‐associated malignancies.\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Anne-Marie Pulichino, Sophie Vallette-Kasic, Catherine Couture, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Human and mouse TPIT gene mutations cause early onset pituitary ACTH deficiency."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes Dev (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1101/gad.1065603"}], "href": "https://doi.org/10.1101/gad.1065603"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12651888"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12651888"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Sophie Vallette-Kasic, Thierry Brue, Anne-Marie Pulichino, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Congenital isolated adrenocorticotropin deficiency: an underestimated cause of neonatal death, explained by TPIT gene mutations."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Endocrinol Metab (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1210/jc.2004-1300"}], "href": "https://doi.org/10.1210/jc.2004-1300"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15613420"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15613420"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Mario Maira, Catherine Couture, Gwendal Le Martelot, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The T-box factor Tpit recruits SRC/p160 co-activators and mediates hormone action."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M305626200"}], "href": "https://doi.org/10.1074/jbc.M305626200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12970370"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12970370"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "C Couture, A Saveanu, A Barlier, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Phenotypic homogeneity and genotypic variability in a large series of congenital isolated ACTH-deficiency patients with TPIT gene mutations."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Endocrinol Metab (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1210/jc.2011-1659"}], "href": "https://doi.org/10.1210/jc.2011-1659"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22170728"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22170728"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "L A Metherell, M O Savage, M Dattani, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TPIT mutations are associated with early-onset, but not late-onset isolated ACTH deficiency."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur J Endocrinol (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1530/eje.0.1510463"}], "href": "https://doi.org/10.1530/eje.0.1510463"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15476446"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15476446"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Naomi Weintrob, Jacques Drouin, Sophie Vallette-Kasic, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Low estriol levels in the maternal triple-marker screen as a predictor of isolated adrenocorticotropic hormone deficiency caused by a new mutation in the TPIT gene."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pediatrics (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1542/peds.2005-1973"}], "href": "https://doi.org/10.1542/peds.2005-1973"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16390921"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16390921"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Sophie Vallette-Kasic, Catherine Couture, Aurelio Balsalobre, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The TPIT gene mutation M86R associated with isolated adrenocorticotropin deficiency interferes with protein: protein interactions."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Endocrinol Metab (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1210/jc.2007-0284"}], "href": "https://doi.org/10.1210/jc.2007-0284"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17652218"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17652218"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Lionel Budry, Catherine Couture, Aurélio Balsalobre, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Ets factor Etv1 interacts with Tpit protein for pituitary pro-opiomelanocortin (POMC) gene transcription."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M110.202788"}], "href": "https://doi.org/10.1074/jbc.M110.202788"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21622576"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21622576"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Zehra Yavas Abali, Gozde Yesil, Tarik Kirkgoz, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Evaluation of growth and puberty in a child with a novel TBX19 gene mutation and review of the literature."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hormones (Athens) (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s42000-019-00096-7"}], "href": "https://doi.org/10.1007/s42000-019-00096-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30747411"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30747411"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Aslı Derya Kardelen Al, Şükran Poyrazoğlu, Ayça Aslanger, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A Rare Cause of Adrenal Insufficiency - Isolated ACTH Deficiency Due to TBX19 Mutation: Long-Term Follow-Up of Two Cases and Review of the Literature."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Horm Res Paediatr (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1159/000506740"}], "href": "https://doi.org/10.1159/000506740"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32344415"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32344415"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Shengnan Wu, Qiong Chen, Linghua Shen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "[Analysis of TBX19 gene variant in a child with congenital isolated adrenocorticotropic hormone deficiency]."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Zhonghua Yi Xue Yi Chuan Xue Za Zhi (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3760/cma.j.cn511374-20191107-00563"}], "href": "https://doi.org/10.3760/cma.j.cn511374-20191107-00563"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33423260"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33423260"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Silvia Uccella, Eleonora Leoni, Simon Kaiser, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Heterogeneity of TPIT expression in ACTH-secreting extra-pituitary neuroendocrine tumors (NETs) supports the existence of different cellular programs in pancreatic and pulmonary NETs."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Virchows Arch (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00428-023-03642-2"}], "href": "https://doi.org/10.1007/s00428-023-03642-2"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37726450"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37726450"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Théo Charnay, Gregory Mougel, Cyril Amouroux, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A novel "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "TBX19"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " gene mutation in patients with isolated ACTH deficiency from distinct families with a common geographical origin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Front Endocrinol (Lausanne) (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3389/fendo.2022.1080649"}], "href": "https://doi.org/10.3389/fendo.2022.1080649"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36890856"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36890856"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "D Wasserman, T Geijer, M Sokolowski, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic variation in the hypothalamic-pituitary-adrenocortical axis regulatory factor, T-box 19, and the angry/hostility personality trait."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes Brain Behav (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1601-183X.2006.00259.x"}], "href": "https://doi.org/10.1111/j.1601-183X.2006.00259.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16899054"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16899054"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Xiaoyu Ji, Xiaoping Chen, Bixiang Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "T-box transcription factor 19 promotes hepatocellular carcinoma metastasis through upregulating EGFR and RAC1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncogene (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41388-022-02249-2"}], "href": "https://doi.org/10.1038/s41388-022-02249-2"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35217793"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35217793"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Jin Ando, Motonobu Saito, Jun-Ichi Imai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TBX19 is overexpressed in colorectal cancer and associated with lymph node metastasis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Fukushima J Med Sci (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.5387/fms.2017-08"}], "href": "https://doi.org/10.5387/fms.2017-08"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29199261"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29199261"}]}]}]}
Synonyms	TBS19, TPIT, DJ747L4.1
Proteins	TBX19_HUMAN
NCBI Gene ID	9095
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

TBX19 has 4,298 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, disease, phenotype or trait, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 109 datasets.

Click the + buttons to view associations for TBX19 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

TBX19 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of TBX19 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of TBX19 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of TBX19 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of TBX19 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of TBX19 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of TBX19 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of TBX19 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of TBX19 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of TBX19 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of TBX19 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of TBX19 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of TBX19 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with TBX19 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of TBX19 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of TBX19 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of TBX19 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations	phenotypes associated with TBX19 gene from the curated ClinVar Gene-Phenotype Associations dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with TBX19 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of TBX19 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing TBX19 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing TBX19 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing TBX19 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with TBX19 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with TBX19 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of TBX19 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with TBX19 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with TBX19 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with TBX19 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by TBX19 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with TBX19 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with TBX19 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with TBX19 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with TBX19 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at TBX19 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of TBX19 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of TBX19 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing TBX19 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with TBX19 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with TBX19 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of TBX19 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.