TIPARP Gene

HGNC Family	Poly (ADP-ribose) polymerases (PARP)
Name	TCDD-inducible poly(ADP-ribose) polymerase
Description	This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nTIPARP (also known as PARP7) is a mono‐ADP‐ribosyltransferase that plays a central role in regulating transcription factor and nuclear receptor activities. It exerts negative feedback on ligand‐activated receptors such as the aryl hydrocarbon receptor (AHR), hypoxia‐inducible factor‐1 (HIF‐1), liver X receptors (LXRs), estrogen receptor α (ERα) and androgen receptor (AR) by catalyzing site‐specific mono‐ADP‐ribosylation of these transcription factors, thereby promoting their ubiquitination and degradation or modulating their interactions with co-regulators. Moreover, TIPARP forms distinct nuclear condensates that facilitate the recruitment of specific E3 ubiquitin ligases, while its expression is also regulated by AHR and AR via both transcriptional and post-transcriptional mechanisms."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "9"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn addition to its role in transcriptional regulation, TIPARP is a key modulator of innate immune responses and antiviral defense. It functions as a pattern recognition receptor by binding viral RNAs through its zinc finger domain and facilitating their degradation via the recruitment of exosome complexes. Furthermore, TIPARP‐mediated mono-ADP‐ribosylation of immune regulatory proteins such as PARP13 modulates nucleic acid sensing in tumor cells, while changes in TIPARP expression have been linked to reduced astrocyte activation in stroke models. Collectively, these mechanisms underscore its importance in host antiviral defenses against RNA viruses and emerging alphaviruses."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "10", "end_ref": "14"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nTIPARP is also implicated in cancer and other disease‐related cellular processes. Genome‐wide analyses and gene amplification studies have identified TIPARP as a candidate risk gene in ovarian and head-and-neck cancers, where its ADP‐ribosylation activity affects cell adhesion, microtubule dynamics, and cytoskeletal regulation. Moreover, TIPARP-mediated ADP‐ribosylation of key oncogenic drivers—such as FRA1 in lung and breast cancers as well as AR in prostate cancer—can influence cell proliferation, migration and therapeutic responses. In the eye, TIPARP modulates extracellular matrix composition and cytoskeletal proteins in trabecular meshwork cells, thereby contributing to the regulation of intraocular pressure and presenting a potential target for glaucoma therapy."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "15", "end_ref": "20"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Laura MacPherson, Shaimaa Ahmed, Laura Tamblyn, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Aryl hydrocarbon receptor repressor and TiPARP (ARTD14) use similar, but also distinct mechanisms to repress aryl hydrocarbon receptor signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Sci (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/ijms15057939"}], "href": "https://doi.org/10.3390/ijms15057939"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24806346"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24806346"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Christian Bindesbøll, Susanna Tan, Debbie Bott, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem J (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1042/BJ20151077"}], "href": "https://doi.org/10.1042/BJ20151077"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26814197"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26814197"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Giulia Grimaldi, Sharanya Rajendra, Jason Matthews "}, {"type": "b", "children": [{"type": "t", "text": "The aryl hydrocarbon receptor regulates the expression of TIPARP and its cis long non-coding RNA, TIPARP-AS1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2017.12.113"}], "href": "https://doi.org/10.1016/j.bbrc.2017.12.113"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29274782"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29274782"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Alvin Gomez, Christian Bindesbøll, Somisetty V Satheesh, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem J (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1042/BCJ20180347"}], "href": "https://doi.org/10.1042/BCJ20180347"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30373764"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30373764"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Lu Zhang, Ji Cao, Longying Dong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TiPARP forms nuclear condensates to degrade HIF-1α and suppress tumorigenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1921815117"}], "href": "https://doi.org/10.1073/pnas.1921815117"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32482854"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32482854"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Teddy Kamata, Chun-Song Yang, Tiffany A Melhuish, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Post-Transcriptional Regulation of PARP7 Protein Stability Is Controlled by Androgen Signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cells (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/cells10020363"}], "href": "https://doi.org/10.3390/cells10020363"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33572475"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33572475"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Marit Rasmussen, Susanna Tan, Venkata S Somisetty, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PARP7 and Mono-ADP-Ribosylation Negatively Regulate Estrogen Receptor α Signaling in Human Breast Cancer Cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cells (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/cells10030623"}], "href": "https://doi.org/10.3390/cells10030623"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33799807"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33799807"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Chun-Song Yang, Kasey Jividen, Teddy Kamata, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-021-23055-6"}], "href": "https://doi.org/10.1038/s41467-021-23055-6"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33976187"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33976187"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Teddy Kamata, Chun-Song Yang, Bryce M Paschal "}, {"type": "b", "children": [{"type": "t", "text": "PARP7 mono-ADP-ribosylates the agonist conformation of the androgen receptor in the nucleus."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem J (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1042/BCJ20210378"}], "href": "https://doi.org/10.1042/BCJ20210378"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34264286"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34264286"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Tatsuya Kozaki, Jun Komano, Daiki Kanbayashi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1621508114"}], "href": "https://doi.org/10.1073/pnas.1621508114"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28213497"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28213497"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Bing Han, Yuan Zhang, Yanhong Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Autophagy (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/15548627.2018.1458173"}], "href": "https://doi.org/10.1080/15548627.2018.1458173"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29938598"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29938598"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Kelsie M Rodriguez, Sara C Buch-Larsen, Ilsa T Kirby, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Elife (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7554/eLife.60480"}], "href": "https://doi.org/10.7554/eLife.60480"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33475084"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33475084"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Joseph M Gozgit, Melissa M Vasbinder, Ryan P Abo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Cell (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ccell.2021.06.018"}], "href": "https://doi.org/10.1016/j.ccell.2021.06.018"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34375612"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34375612"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Houqi Jiao, Ziqing Yan, Xiaofeng Zhai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Transcriptome screening identifies TIPARP as an antiviral host factor against the Getah virus."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Virol (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/jvi.00591-23"}], "href": "https://doi.org/10.1128/jvi.00591-23"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37768084"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37768084"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Masuko Katoh, Masaru Katoh "}, {"type": "b", "children": [{"type": "t", "text": "Identification and characterization of human TIPARP gene within the CCNL amplicon at human chromosome 3q25.31."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Oncol (2003)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12851707"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12851707"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Ellen L Goode, Georgia Chenevix-Trench, Honglin Song, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng.668"}], "href": "https://doi.org/10.1038/ng.668"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20852632"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20852632"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Lavanya H Palavalli Parsons, Sridevi Challa, Bryan A Gibson, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of PARP-7 substrates reveals a role for MARylation in microtubule control in ovarian cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Elife (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7554/eLife.60481"}], "href": "https://doi.org/10.7554/eLife.60481"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33475085"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33475085"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Youjia Zhang, Maomao Song, Yingwen Bi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TIPARP is involved in the regulation of intraocular pressure."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Commun Biol (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s42003-022-04346-0"}], "href": "https://doi.org/10.1038/s42003-022-04346-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36536086"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36536086"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Chunsong Yang, Krzysztof Wierbiłowicz, Natalia M Dworak, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res Commun (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/2767-9764.CRC-23-0086"}], "href": "https://doi.org/10.1158/2767-9764.CRC-23-0086"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37077937"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37077937"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Patrick Manetsch, Flurina Böhi, Kathrin Nowak, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PARP7-mediated ADP-ribosylation of FRA1 promotes cancer cell growth by repressing IRF1- and IRF3-dependent apoptosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.2309047120"}], "href": "https://doi.org/10.1073/pnas.2309047120"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38011562"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38011562"}]}]}]}
Synonyms	ARTD14, PART14, PARP7
Proteins	PARPT_HUMAN
NCBI Gene ID	25976
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

TIPARP has 13,498 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 116 datasets.

Click the + buttons to view associations for TIPARP from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

TIPARP Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of TIPARP gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of TIPARP gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of TIPARP gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of TIPARP gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of TIPARP gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of TIPARP gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of TIPARP gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of TIPARP gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of TIPARP gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of TIPARP gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of TIPARP gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with TIPARP gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of TIPARP gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of TIPARP gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of TIPARP gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of TIPARP gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing TIPARP protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing TIPARP protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing TIPARP protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing TIPARP protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with TIPARP protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with TIPARP protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of TIPARP gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with TIPARP gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with TIPARP gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with TIPARP gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with TIPARP gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by TIPARP gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with TIPARP gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with TIPARP gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with TIPARP gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with TIPARP gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with TIPARP gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with TIPARP gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at TIPARP gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of TIPARP gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of TIPARP gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing TIPARP from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with TIPARP gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with TIPARP gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.