TMEM225B Gene

Name	transmembrane protein 225B
Description	Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]
NCBI Gene ID	100289187
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

TMEM225B has 1,165 functional associations with biological entities spanning 6 categories (functional term, phrase or reference, disease, phenotype or trait, chemical, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 15 datasets.

Click the + buttons to view associations for TMEM225B from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

TMEM225B Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of TMEM225B gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with TMEM225B gene from the CellMarker Gene-Cell Type Associations dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of TMEM225B gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with TMEM225B protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with TMEM225B gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with TMEM225B gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	GTEx eQTL 2025	SNPs regulating expression of TMEM225B gene from the GTEx eQTL 2025 dataset.
	GTEx Tissue Gene Expression Profiles 2023	tissues with high or low expression of TMEM225B gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset.
	GTEx Tissue-Specific Aging Signatures	tissue samples with high or low expression of TMEM225B gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.
	JASPAR Predicted Human Transcription Factor Targets 2025	transcription factors regulating expression of TMEM225B gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	drug perturbations changing expression of TMEM225B gene from the NIBR DRUG-seq U2OS MoA Box dataset.
	Rummagene Transcription Factor Associations 2026	transcription factors regulating expression of TMEM225B gene from the Rummagene Transcription Factor Associations 2026 dataset.
	RummaGEO Drug Perturbation Signatures	drug perturbations changing expression of TMEM225B gene from the RummaGEO Drug Perturbation Signatures dataset.
	RummaGEO Gene Perturbation Signatures	gene perturbations changing expression of TMEM225B gene from the RummaGEO Gene Perturbation Signatures dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	tissues co-occuring with TMEM225B protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset.