TOPORS-AS1 Gene

Name	TOPORS antisense RNA 1
Description	Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]
Synonyms	C9ORF133, SMIM27
NCBI Gene ID	100129250
API
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

TOPORS-AS1 has 1,173 functional associations with biological entities spanning 5 categories (disease, phenotype or trait, functional term, phrase or reference, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 22 datasets.

Click the + buttons to view associations for TOPORS-AS1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

TOPORS-AS1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of TOPORS-AS1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of TOPORS-AS1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of TOPORS-AS1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of TOPORS-AS1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of TOPORS-AS1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	DisGeNET Gene-Disease Associations	diseases associated with TOPORS-AS1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with TOPORS-AS1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing TOPORS-AS1 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of TOPORS-AS1 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	kinase perturbations changing expression of TOPORS-AS1 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of TOPORS-AS1 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	transcription factor perturbations changing expression of TOPORS-AS1 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of TOPORS-AS1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	GTEx Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of TOPORS-AS1 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of TOPORS-AS1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	cell lines with high or low expression of TOPORS-AS1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.
	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	gene perturbations changing expression of TOPORS-AS1 gene from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
	LOCATE Predicted Protein Localization Annotations	cellular components predicted to contain TOPORS-AS1 protein from the LOCATE Predicted Protein Localization Annotations dataset.
	MotifMap Predicted Transcription Factor Targets	transcription factors regulating expression of TOPORS-AS1 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of TOPORS-AS1 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	gene perturbations changing expression of TOPORS-AS1 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	cell types and tissues with high or low DNA methylation of TOPORS-AS1 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.