TRA Gene

HGNC Family	T cell receptors (TR)
Name	T cell receptor alpha locus
Synonyms	TRAC, IMD7, TRA@
NCBI Gene ID	6955
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

TRA has 891 functional associations with biological entities spanning 6 categories (molecular profile, functional term, phrase or reference, chemical, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 22 datasets.

Click the + buttons to view associations for TRA from the datasets below.

If available, associations are ranked by standardized value

Harmonizome

TRA Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference:

Funding

	Dataset	Summary
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of TRA gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Biocarta Pathways	pathways involving TRA protein from the Biocarta Pathways dataset.
	CHEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of TRA gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	CHEA Transcription Factor Targets	transcription factors binding the promoter of TRA gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of TRA gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing TRA protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of TRA gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	CTD Gene-Disease Associations	diseases associated with TRA gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with TRA gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	GAD Gene-Disease Associations	diseases associated with TRA gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with TRA gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of TRA gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with TRA gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of TRA gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of TRA gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GWAS Catalog SNP-Phenotype Associations	phenotypes associated with TRA gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.
	Hub Proteins Protein-Protein Interactions	interacting hub proteins for TRA from the curated Hub Proteins Protein-Protein Interactions dataset.
	HuGE Navigator Gene-Phenotype Associations	phenotypes associated with TRA gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
	MotifMap Predicted Transcription Factor Targets	transcription factors regulating expression of TRA gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
	Pathway Commons Protein-Protein Interactions	interacting proteins for TRA from the Pathway Commons Protein-Protein Interactions dataset.
	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	cell types and tissues with high or low DNA methylation of TRA gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
	TISSUES Curated Tissue Protein Expression Evidence Scores	tissues with high expression of TRA protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.