| HGNC Family | Zinc fingers, Tripartite motif-containing (TRIM) |
| Name | tripartite motif containing 49D1 |
| Description | Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response and regulation of gene expression. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025] |
| Synonyms | TRIM49D1P, TRIM49D, TRIM49DP, TRIM49D2P |
| Proteins | T49D1_HUMAN |
| NCBI Gene ID | 399939 |
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| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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TRIM49D1 has 207 functional associations with biological entities spanning 4 categories (chemical, functional term, phrase or reference, cell line, cell type or tissue, gene, protein or microRNA) extracted from 11 datasets.
Click the + buttons to view associations for TRIM49D1 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CM4AI KOLF21J CRISPRi Gene Perturbation Atlas | gene perturbations changing expression of TRIM49D1 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset. | |
| DepMap CRISPR Gene Dependency | cell lines with fitness changed by TRIM49D1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
| GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of TRIM49D1 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of TRIM49D1 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GO Biological Process Annotations 2023 | biological processes involving TRIM49D1 gene from the curated GO Biological Process Annotations 2023 dataset. | |
| GO Molecular Function Annotations 2023 | molecular functions performed by TRIM49D1 gene from the curated GO Molecular Function Annotations 2023 dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of TRIM49D1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of TRIM49D1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain TRIM49D1 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| Rummagene Transcription Factor Associations 2026 | transcription factors regulating expression of TRIM49D1 gene from the Rummagene Transcription Factor Associations 2026 dataset. | |
| TargetScan Predicted Nonconserved microRNA Targets | microRNAs regulating expression of TRIM49D1 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset. | |
