TTTY3 Gene

Name testis-specific transcript, Y-linked 3 (non-protein coding)
Description There are two copies of this gene within the P1 palindrome on chromosome Y. This record represents the more telomeric copy. [provided by RefSeq, Jul 2008]
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe provided abstract (PMID"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "focuses on deciphering the regulatory mechanisms underlying the transcription of the GCET gene in germinal center B cells rather than detailing any function for TTTY3. Specifically, the study characterizes a TATA‐less promoter positioned immediately upstream of multiple transcription start sites and shows that full promoter activity depends on the presence of a non‐consensus Sp binding site, which serves as a docking site for Spl and Sp3 transcription factors. In brief, while the investigation offers valuable insight into the cell type–specific expression of GCET via defined promoter modules and transcription factor interactions, it does not provide any information regarding the function or regulation of TTTY3.\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "John W Steinke, Wendy Hodsdon, Sarah Parenti, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of an Sp factor-dependent promoter in GCET, a gene expressed at high levels in germinal center B cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Immunol (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molimm.2004.06.031"}], "href": "https://doi.org/10.1016/j.molimm.2004.06.031"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15482850"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15482850"}]}]}]}
Synonyms TTTY3A, TTY3, NCRNA00121, LINC00121
NCBI Gene ID 114760
API
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Predicted Functions View TTTY3's ARCHS4 Predicted Functions.
Co-expressed Genes View TTTY3's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View TTTY3's ARCHS4 Predicted Functions.

Functional Associations

TTTY3 has 108 functional associations with biological entities spanning 5 categories (molecular profile, organism, functional term, phrase or reference, cell line, cell type or tissue, gene, protein or microRNA) extracted from 6 datasets.

Click the + buttons to view associations for TTTY3 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of TTTY3 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of TTTY3 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
GeneSigDB Published Gene Signatures PubMedIDs of publications reporting gene signatures containing TTTY3 from the GeneSigDB Published Gene Signatures dataset.
GEO Signatures of Differentially Expressed Genes for Viral Infections virus perturbations changing expression of TTTY3 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of TTTY3 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of TTTY3 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.