TVP23C-CDRT4 Gene

Name	TVP23C-CDRT4 readthrough
Description	This locus represents naturally occurring readthrough transcription between the neighboring TVP23C (trans-golgi network vesicle protein 23 homolog) and CDRT4 (CMT1A duplicated region transcript 4) genes on chromosome 17. Alternative splicing results in multiple transcript variants, one of which encodes a protein that shares sequence identity with the upstream gene product, but its C-terminus is distinct due to frameshifts relative to the downstream gene. [provided by RefSeq, Apr 2014]
Synonyms	TVP23C, FAM18B2-CDRT4
NCBI Gene ID	100533496
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

TVP23C-CDRT4 has 1,848 functional associations with biological entities spanning 8 categories (molecular profile, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 40 datasets.

Click the + buttons to view associations for TVP23C-CDRT4 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

TVP23C-CDRT4 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of TVP23C-CDRT4 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of TVP23C-CDRT4 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of TVP23C-CDRT4 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing TVP23C-CDRT4 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with TVP23C-CDRT4 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of TVP23C-CDRT4 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with TVP23C-CDRT4 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at TVP23C-CDRT4 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of TVP23C-CDRT4 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of TVP23C-CDRT4 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of TVP23C-CDRT4 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GO Biological Process Annotations 2025	biological processes involving TVP23C-CDRT4 gene from the curated GO Biological Process Annotations2025 dataset.
	GO Cellular Component Annotations 2025	cellular components containing TVP23C-CDRT4 protein from the curated GO Cellular Component Annotations 2025 dataset.
	GTEx eQTL 2025	SNPs regulating expression of TVP23C-CDRT4 gene from the GTEx eQTL 2025 dataset.
	GWAS Catalog SNP-Phenotype Associations 2025	phenotypes associated with TVP23C-CDRT4 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.
	GWASdb SNP-Disease Associations	diseases associated with TVP23C-CDRT4 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.
	GWASdb SNP-Phenotype Associations	phenotypes associated with TVP23C-CDRT4 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.
	HPA Cell Line Gene Expression Profiles	cell lines with high or low expression of TVP23C-CDRT4 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
	HPA Tissue Gene Expression Profiles	tissues with high or low expression of TVP23C-CDRT4 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
	HPA Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of TVP23C-CDRT4 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset.
	InterPro Predicted Protein Domain Annotations	protein domains predicted for TVP23C-CDRT4 protein from the InterPro Predicted Protein Domain Annotations dataset.
	JASPAR Predicted Human Transcription Factor Targets 2025	transcription factors regulating expression of TVP23C-CDRT4 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
	JASPAR Predicted Mouse Transcription Factor Targets 2025	transcription factors regulating expression of TVP23C-CDRT4 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of TVP23C-CDRT4 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of TVP23C-CDRT4 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	cell lines with high or low expression of TVP23C-CDRT4 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.
	MotifMap Predicted Transcription Factor Targets	transcription factors regulating expression of TVP23C-CDRT4 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	drug perturbations changing expression of TVP23C-CDRT4 gene from the NIBR DRUG-seq U2OS MoA Box dataset.
	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	cell types and tissues with high or low DNA methylation of TVP23C-CDRT4 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of TVP23C-CDRT4 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue Gene Expression Profiles dataset.
	Roadmap Epigenomics Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at TVP23C-CDRT4 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
	Rummagene Transcription Factor Associations 2026	transcription factors regulating expression of TVP23C-CDRT4 gene from the Rummagene Transcription Factor Associations 2026 dataset.
	RummaGEO Drug Perturbation Signatures	drug perturbations changing expression of TVP23C-CDRT4 gene from the RummaGEO Drug Perturbation Signatures dataset.
	RummaGEO Gene Perturbation Signatures	gene perturbations changing expression of TVP23C-CDRT4 gene from the RummaGEO Gene Perturbation Signatures dataset.
	Tabula Sapiens Gene-Cell Associations	cell types with high or low expression of TVP23C-CDRT4 gene relative to other cell types from the Tabula Sapiens Gene-Cell Associations dataset.
	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	drug perturbations changing expression of TVP23C-CDRT4 gene from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
	TargetScan Predicted Conserved microRNA Targets	microRNAs regulating expression of TVP23C-CDRT4 gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.
	TargetScan Predicted Nonconserved microRNA Targets	microRNAs regulating expression of TVP23C-CDRT4 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.
	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	tissues with high expression of TVP23C-CDRT4 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	tissues co-occuring with TVP23C-CDRT4 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset.