| HGNC Family | Glycosyltransferases |
| Name | UDP glucuronosyltransferase 1 family, polypeptide A9 |
| Description | This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq, Jul 2008] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nUDP‐glucuronosyltransferase 1A9 (UGT1A9) is a liver‐enriched enzyme that plays a central role in catalyzing glucuronidation reactions to detoxify a broad spectrum of endogenous compounds and xenobiotics. It is instrumental in the inactivation and clearance of clinically relevant compounds, such as the active metabolite SN‑38 of irinotecan, mycophenolic acid, and even carcinogenic catecholestrogens. Molecular characterization studies have identified promoter variants—including the UGT1A9*22 allele with a thymidine insertion that enhances transcription—and demonstrated that expression of UGT1A9 is under the control of liver‐specific transcription factors such as HNF4α. These findings underscore its pivotal role in hepatic drug metabolism and detoxification."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "5"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nFunctional investigations have revealed that specific genetic polymorphisms of UGT1A9—including promoter single‐nucleotide polymorphisms (such as –275T>A and –2152C>T) and amino acid substitutions (for example, M33T and C3Y)—can significantly modify its catalytic activity and substrate affinity. Such changes have been shown to influence the pharmacokinetics of drugs like irinotecan and mycophenolic acid—impacting both therapeutic efficacy and toxicity profiles—as demonstrated in various patient cohorts and integrated pharmacogenetic models. These studies collectively highlight the enzyme’s importance as a genetic determinant in personalized medicine strategies, accounting for interindividual variability in drug metabolism."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "6", "end_ref": "15"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nMoreover, UGT1A9’s substrate versatility extends to extrahepatic processes, such as ethanol glucuronidation, where it demonstrates the highest intrinsic clearance among UGT isoforms—further emphasizing its broad role in xenobiotic metabolism. Together, the collective data indicate that UGT1A9 is not only crucial for determining the balance between active and inactive drug metabolites but also holds significant promise as a pharmacogenetic marker to guide individualized therapeutic regimens."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "16"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Hiroyuki Yamanaka, Miki Nakajima, Miki Katoh, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A novel polymorphism in the promoter region of human UGT1A9 gene (UGT1A9*22) and its effects on the transcriptional activity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pharmacogenetics (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/00008571-200405000-00008"}], "href": "https://doi.org/10.1097/00008571-200405000-00008"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15115919"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15115919"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Olivier Bernard, Chantal Guillemette "}, {"type": "b", "children": [{"type": "t", "text": "The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variants."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Drug Metab Dispos (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1124/dmd.32.8.775"}], "href": "https://doi.org/10.1124/dmd.32.8.775"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15258099"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15258099"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Hugo Girard, Michael H Court, Olivier Bernard, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pharmacogenetics (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/01.fpc.0000114754.08559.27"}], "href": "https://doi.org/10.1097/01.fpc.0000114754.08559.27"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15284532"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15284532"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Olivier Barbier, Hugo Girard, Yusuke Inoue, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Pharmacol (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1124/mol.104.003863"}], "href": "https://doi.org/10.1124/mol.104.003863"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15470081"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15470081"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Federico Innocenti, Wanqing Liu, Peixian Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Haplotypes of variants in the UDP-glucuronosyltransferase1A9 and 1A1 genes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pharmacogenet Genomics (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/01213011-200505000-00004"}], "href": "https://doi.org/10.1097/01213011-200505000-00004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15864130"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15864130"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Dirk R J Kuypers, Maarten Naesens, Severine Vermeire, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The impact of uridine diphosphate-glucuronosyltransferase 1A9 (UGT1A9) gene promoter region single-nucleotide polymorphisms T-275A and C-2152T on early mycophenolic acid dose-interval exposure in de novo renal allograft recipients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Pharmacol Ther (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.clpt.2005.06.007"}], "href": "https://doi.org/10.1016/j.clpt.2005.06.007"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16198654"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16198654"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Jean Thibaudeau, Johanie Lépine, Jelena Tojcic, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/0008-5472.CAN-05-2857"}], "href": "https://doi.org/10.1158/0008-5472.CAN-05-2857"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16397224"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16397224"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Ji-Youn Han, Hyeong-Seok Lim, Eun Soon Shin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Oncol (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1200/JCO.2005.03.0239"}], "href": "https://doi.org/10.1200/JCO.2005.03.0239"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16636344"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16636344"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "E Lévesque, R Delage, M-O Benoit-Biancamano, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Pharmacol Ther (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.clpt.6100073"}], "href": "https://doi.org/10.1038/sj.clpt.6100073"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17339869"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17339869"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Hironobu Minami, Kimie Sai, Mayumi Saeki, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1"}, {"type": "i", "children": [{"type": "t", "text": "6 and "}]}, {"type": "t", "text": "28."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pharmacogenet Genomics (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/FPC.0b013e328014341f"}], "href": "https://doi.org/10.1097/FPC.0b013e328014341f"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17558305"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17558305"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Ji-Youn Han, Hyeong-Seok Lim, Yong Hoon Park, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Integrated pharmacogenetic prediction of irinotecan pharmacokinetics and toxicity in patients with advanced non-small cell lung cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Lung Cancer (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.lungcan.2007.12.003"}], "href": "https://doi.org/10.1016/j.lungcan.2007.12.003"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18221820"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18221820"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Zheng Jiao, Jun-Jie Ding, Jie Shen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Population pharmacokinetic modelling for enterohepatic circulation of mycophenolic acid in healthy Chinese and the influence of polymorphisms in UGT1A9."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Br J Clin Pharmacol (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1365-2125.2008.03109.x"}], "href": "https://doi.org/10.1111/j.1365-2125.2008.03109.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18279479"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18279479"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Erika Cecchin, Federico Innocenti, Mario D'Andrea, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Oncol (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1200/JCO.2008.19.0314"}], "href": "https://doi.org/10.1200/JCO.2008.19.0314"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19364970"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19364970"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "R H N van Schaik, M van Agteren, J W de Fijter, et al. "}, {"type": "b", "children": [{"type": "t", "text": "UGT1A9 -275T>A/-2152C>T polymorphisms correlate with low MPA exposure and acute rejection in MMF/tacrolimus-treated kidney transplant patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Pharmacol Ther (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/clpt.2009.83"}], "href": "https://doi.org/10.1038/clpt.2009.83"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19494809"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19494809"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Wei Zhao, May Fakhoury, Georges Deschênes, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Population pharmacokinetics and pharmacogenetics of mycophenolic acid following administration of mycophenolate mofetil in de novo pediatric renal-transplant patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Pharmacol (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1177/0091270009357429"}], "href": "https://doi.org/10.1177/0091270009357429"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20147615"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20147615"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Alaa Al Saabi, Delphine Allorge, François-Ludovic Sauvage, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Involvement of UDP-glucuronosyltransferases UGT1A9 and UGT2B7 in ethanol glucuronidation, and interactions with common drugs of abuse."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Drug Metab Dispos (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1124/dmd.112.047878"}], "href": "https://doi.org/10.1124/dmd.112.047878"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23230132"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23230132"}]}]}]}
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| Synonyms | UGT1A9S, LUGP4, UGT1.9, UGT1AI, UGT-1I, UGT1-9, UGT1I, UDPGT 1-9, UGT1-09, HLUGP4 |
| Proteins | UD19_HUMAN |
| NCBI Gene ID | 54600 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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UGT1A9 has 3,616 functional associations with biological entities spanning 8 categories (molecular profile, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 86 datasets.
Click the + buttons to view associations for UGT1A9 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of UGT1A9 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
| Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of UGT1A9 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset. | |
| Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of UGT1A9 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
| Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of UGT1A9 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of UGT1A9 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| CellMarker Gene-Cell Type Associations | cell types associated with UGT1A9 gene from the CellMarker Gene-Cell Type Associations dataset. | |
| ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of UGT1A9 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
| ChEA Transcription Factor Targets | transcription factors binding the promoter of UGT1A9 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
| ChEA Transcription Factor Targets 2022 | transcription factors binding the promoter of UGT1A9 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. | |
| CM4AI KOLF21J CRISPRi Gene Perturbation Atlas | gene perturbations changing expression of UGT1A9 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores | cellular components containing UGT1A9 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores 2025 | cellular components containing UGT1A9 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset. | |
| COMPARTMENTS Text-mining Protein Localization Evidence Scores | cellular components co-occuring with UGT1A9 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset. | |
| COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 | cellular components co-occuring with UGT1A9 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of UGT1A9 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| COSMIC Cell Line Gene Mutation Profiles | cell lines with UGT1A9 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
| CTD Gene-Chemical Interactions | chemicals interacting with UGT1A9 gene/protein from the curated CTD Gene-Chemical Interactions dataset. | |
| CTD Gene-Disease Associations | diseases associated with UGT1A9 gene/protein from the curated CTD Gene-Disease Associations dataset. | |
| dbGAP Gene-Trait Associations | traits associated with UGT1A9 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset. | |
| DepMap CRISPR Gene Dependency | cell lines with fitness changed by UGT1A9 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
| DGIdb Drug Targets 2026 | interacting drugs for UGT1A9 protein from the DGIdb Drug Targets 2026 dataset. | |
| DISEASES Experimental Gene-Disease Association Evidence Scores 2025 | diseases associated with UGT1A9 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset. | |
| DISEASES Text-mining Gene-Disease Association Evidence Scores | diseases co-occuring with UGT1A9 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset. | |
| DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 | diseases co-occuring with UGT1A9 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. | |
| DisGeNET Gene-Disease Associations | diseases associated with UGT1A9 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. | |
| DisGeNET Gene-Phenotype Associations | phenotypes associated with UGT1A9 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset. | |
| DrugBank Drug Targets | interacting drugs for UGT1A9 protein from the curated DrugBank Drug Targets dataset. | |
| ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at UGT1A9 gene from the ENCODE Histone Modification Site Profiles dataset. | |
| ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of UGT1A9 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
| ENCODE Transcription Factor Targets | transcription factors binding the promoter of UGT1A9 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
| GAD Gene-Disease Associations | diseases associated with UGT1A9 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. | |
| GAD High Level Gene-Disease Associations | diseases associated with UGT1A9 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset. | |
| GeneRIF Biological Term Annotations | biological terms co-occuring with UGT1A9 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. | |
| GeneSigDB Published Gene Signatures | PubMedIDs of publications reporting gene signatures containing UGT1A9 from the GeneSigDB Published Gene Signatures dataset. | |
| GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of UGT1A9 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of UGT1A9 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of UGT1A9 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
| GlyGen Glycosylated Proteins | ligands (chemical) binding UGT1A9 protein from the GlyGen Glycosylated Proteins dataset. | |
| GO Biological Process Annotations 2015 | biological processes involving UGT1A9 gene from the curated GO Biological Process Annotations 2015 dataset. | |
| GO Biological Process Annotations 2023 | biological processes involving UGT1A9 gene from the curated GO Biological Process Annotations 2023 dataset. | |
| GO Biological Process Annotations 2025 | biological processes involving UGT1A9 gene from the curated GO Biological Process Annotations2025 dataset. | |
| GO Cellular Component Annotations 2015 | cellular components containing UGT1A9 protein from the curated GO Cellular Component Annotations 2015 dataset. | |
| GO Cellular Component Annotations 2023 | cellular components containing UGT1A9 protein from the curated GO Cellular Component Annotations 2023 dataset. | |
| GO Cellular Component Annotations 2025 | cellular components containing UGT1A9 protein from the curated GO Cellular Component Annotations 2025 dataset. | |
| GO Molecular Function Annotations 2015 | molecular functions performed by UGT1A9 gene from the curated GO Molecular Function Annotations 2015 dataset. | |
| GO Molecular Function Annotations 2023 | molecular functions performed by UGT1A9 gene from the curated GO Molecular Function Annotations 2023 dataset. | |
| GO Molecular Function Annotations 2025 | molecular functions performed by UGT1A9 gene from the curated GO Molecular Function Annotations 2025 dataset. | |
| GTEx eQTL 2025 | SNPs regulating expression of UGT1A9 gene from the GTEx eQTL 2025 dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of UGT1A9 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| GTEx Tissue Gene Expression Profiles 2023 | tissues with high or low expression of UGT1A9 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset. | |
| GWAS Catalog SNP-Phenotype Associations 2025 | phenotypes associated with UGT1A9 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. | |
| HMDB Metabolites of Enzymes | interacting metabolites for UGT1A9 protein from the curated HMDB Metabolites of Enzymes dataset. | |
| HuGE Navigator Gene-Phenotype Associations | phenotypes associated with UGT1A9 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset. | |
| InterPro Predicted Protein Domain Annotations | protein domains predicted for UGT1A9 protein from the InterPro Predicted Protein Domain Annotations dataset. | |
| JASPAR Predicted Human Transcription Factor Targets 2025 | transcription factors regulating expression of UGT1A9 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. | |
| JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of UGT1A9 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
| KEGG Pathways | pathways involving UGT1A9 protein from the KEGG Pathways dataset. | |
| KEGG Pathways 2026 | pathways involving UGT1A9 protein from the KEGG Pathways 2026 dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of UGT1A9 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles | cell lines with UGT1A9 gene mutations from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset. | |
| LOCATE Curated Protein Localization Annotations | cellular components containing UGT1A9 protein in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain UGT1A9 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of UGT1A9 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
| MW Enzyme Metabolite Associations | interacting metabolites for UGT1A9 protein from the MW Gene Metabolite Associations dataset. | |
| NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles | drug perturbations changing expression of UGT1A9 gene from the NIBR DRUG-seq U2OS MoA Box dataset. | |
| Pathway Commons Protein-Protein Interactions | interacting proteins for UGT1A9 from the Pathway Commons Protein-Protein Interactions dataset. | |
| PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of UGT1A9 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| PFOCR Pathway Figure Associations 2024 | pathways involving UGT1A9 protein from the Wikipathways PFOCR 2024 dataset. | |
| Reactome Pathways 2014 | pathways involving UGT1A9 protein from the Reactome Pathways dataset. | |
| Reactome Pathways 2024 | pathways involving UGT1A9 protein from the Reactome Pathways 2024 dataset. | |
| Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles | cell types and tissues with high or low DNA methylation of UGT1A9 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset. | |
| Roadmap Epigenomics Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at UGT1A9 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset. | |
| Rummagene Transcription Factor Associations 2026 | transcription factors regulating expression of UGT1A9 gene from the Rummagene Transcription Factor Associations 2026 dataset. | |
| RummaGEO Drug Perturbation Signatures | drug perturbations changing expression of UGT1A9 gene from the RummaGEO Drug Perturbation Signatures dataset. | |
| RummaGEO Gene Perturbation Signatures | gene perturbations changing expression of UGT1A9 gene from the RummaGEO Gene Perturbation Signatures dataset. | |
| Tahoe Therapeutics Tahoe 100M Perturbation Atlas | drug perturbations changing expression of UGT1A9 gene from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. | |
| TargetScan Predicted Conserved microRNA Targets | microRNAs regulating expression of UGT1A9 gene predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset. | |
| TargetScan Predicted Nonconserved microRNA Targets | microRNAs regulating expression of UGT1A9 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset. | |
| TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of UGT1A9 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |
| TISSUES Curated Tissue Protein Expression Evidence Scores | tissues with high expression of UGT1A9 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset. | |
| TISSUES Curated Tissue Protein Expression Evidence Scores 2025 | tissues with high expression of UGT1A9 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset. | |
| TISSUES Experimental Tissue Protein Expression Evidence Scores | tissues with high expression of UGT1A9 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset. | |
| TISSUES Text-mining Tissue Protein Expression Evidence Scores | tissues co-occuring with UGT1A9 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset. | |
| TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 | tissues co-occuring with UGT1A9 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset. | |
| WikiPathways Pathways 2014 | pathways involving UGT1A9 protein from the Wikipathways Pathways 2014 dataset. | |
| WikiPathways Pathways 2024 | pathways involving UGT1A9 protein from the WikiPathways Pathways 2024 dataset. | |
