YEATS4 Gene

Name	YEATS domain containing 4
Description	The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nYEATS4 is frequently amplified and overexpressed in a variety of human tumors, where it functions as a potent oncogene by attenuating the p53 tumor suppressor pathway. Enhanced expression of YEATS4 leads to p53 inactivation through mechanisms such as altered phosphorylation and transcriptional repression of critical cell cycle regulators, thereby abrogating senescence and promoting cell survival. These alterations not only contribute to tumor progression in soft tissue sarcomas, non‐small cell lung cancer, and glioma but are also linked to resistance against chemotherapeutic agents."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "6"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nAside from its role in cell cycle regulation, the YEATS domain of YEATS4 functions as a chromatin “reader” that recognizes specific posttranslational histone modifications. It preferentially binds acetylated histone marks (such as H3K27 and H3K14) and even succinyl-lysine modifications, thereby promoting histone variant H2A.Z deposition and facilitating transcriptional activation via interactions with general transcription machinery including TFIIF. These epigenetic functions enable YEATS4 to exert broad control over gene expression programs that support oncogenic transformation."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "7", "end_ref": "10"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nGenetic variation as well as differential regulation of YEATS4 also influence responses to pharmacologic treatments. Genome‐wide association studies have implicated variations near YEATS4 in modulating diastolic blood pressure responses to the thiazide diuretic hydrochlorothiazide, and altered YEATS4 expression has been linked to chemoresistance in colorectal and ovarian cancers. These findings suggest that YEATS4 not only drives oncogenic processes but may also serve as a predictive biomarker for therapeutic responsiveness."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "11", "end_ref": "13"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nMoreover, YEATS4 engages with additional key oncogenic signaling networks beyond p53 regulation. It interacts with Myc family proteins, contributes to chromosomal stability by influencing spindle pole formation, and promotes beta-catenin/TCF signaling in pancreatic cancer, thereby enhancing cellular proliferation, migration, and invasion. These multifaceted interactions underscore the diverse regulatory roles of YEATS4 in tumorigenesis and highlight its potential as a novel target for therapeutic intervention."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "14", "end_ref": "18"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Jeong Hyeon Park, Robert G Roeder "}, {"type": "b", "children": [{"type": "t", "text": "GAS41 is required for repression of the p53 tumor suppressor pathway during normal cellular proliferation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.02185-05"}], "href": "https://doi.org/10.1128/MCB.02185-05"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16705155"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16705155"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Antoine Italiano, Laurence Bianchini, Frédérique Keslair, et al. "}, {"type": "b", "children": [{"type": "t", "text": "HMGA2 is the partner of MDM2 in well-differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Cancer (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/ijc.23380"}], "href": "https://doi.org/10.1002/ijc.23380"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18214854"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18214854"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Jeong Hyeon Park, Rebecca J Smith, Sheau-Yann Shieh, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The GAS41-PP2Cbeta complex dephosphorylates p53 at serine 366 and regulates its stability."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.C110.210211"}], "href": "https://doi.org/10.1074/jbc.C110.210211"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21317290"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21317290"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Larissa A Pikor, William W Lockwood, Kelsie L Thu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "YEATS4 is a novel oncogene amplified in non-small cell lung cancer that regulates the p53 pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/0008-5472.CAN-13-1897"}], "href": "https://doi.org/10.1158/0008-5472.CAN-13-1897"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24170126"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24170126"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Yi Rang Kim, Mi Sung Park, Ki Hwan Eum, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Transcriptome analysis indicates TFEB1 and YEATS4 as regulatory transcription factors for drug resistance of ovarian cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncotarget (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/oncotarget.5208"}], "href": "https://doi.org/10.18632/oncotarget.5208"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26307679"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26307679"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Dhananjaya Pal, Debasmita Mukhopadhyay, M Janaki Ramaiah, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Regulation of Cell Proliferation and Migration by miR-203 via GAS41/miR-10b Axis in Human Glioblastoma Cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0159092"}], "href": "https://doi.org/10.1371/journal.pone.0159092"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27467502"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27467502"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Sabrina Heisel, Nunja C Habel, Nicole Schuetz, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The YEATS family member GAS41 interacts with the general transcription factor TFIIF."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Mol Biol (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1471-2199-11-53"}], "href": "https://doi.org/10.1186/1471-2199-11-53"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20618999"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20618999"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Chih-Chao Hsu, Jiejun Shi, Chao Yuan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Recognition of histone acetylation by the GAS41 YEATS domain promotes H2A.Z deposition in non-small cell lung cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes Dev (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1101/gad.303784.117"}], "href": "https://doi.org/10.1101/gad.303784.117"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29437725"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29437725"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Yi Wang, Jing Jin, Matthew Wai Heng Chung, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1717664115"}], "href": "https://doi.org/10.1073/pnas.1717664115"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29463709"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29463709"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Hyo Je Cho, Hao Li, Brian M Linhares, et al. "}, {"type": "b", "children": [{"type": "t", "text": "GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "ACS Chem Biol (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1021/acschembio.8b00674"}], "href": "https://doi.org/10.1021/acschembio.8b00674"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30071723"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30071723"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Stephen T Turner, Kent R Bailey, Brooke L Fridley, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hypertension (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/HYPERTENSIONAHA.107.104273"}], "href": "https://doi.org/10.1161/HYPERTENSIONAHA.107.104273"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18591461"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18591461"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "J D Duarte, S T Turner, B Tran, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Association of chromosome 12 locus with antihypertensive response to hydrochlorothiazide may involve differential YEATS4 expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pharmacogenomics J (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/tpj.2012.4"}], "href": "https://doi.org/10.1038/tpj.2012.4"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22350108"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22350108"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Qiang Fu, Jing Cheng, Jindai Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Downregulation of YEATS4 by miR-218 sensitizes colorectal cancer cells to L-OHP-induced cell apoptosis by inhibiting cytoprotective autophagy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncol Rep (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/or.2016.5195"}], "href": "https://doi.org/10.3892/or.2016.5195"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27779719"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27779719"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Brenda Lauffart, Scott J Howell, Jason E Tasch, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem J (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1042/0264-6021:3630195"}], "href": "https://doi.org/10.1042/0264-6021:3630195"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11903063"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11903063"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Eugenia Piccinni, Anna Chelstowska, Jakub Hanus, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Direct interaction of Gas41 and Myc encoded by amplified genes in nervous system tumours."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Acta Biochim Pol (2011)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22068108"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22068108"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Jana Schmitt, Ulrike Fischer, Sabrina Heisel, et al. "}, {"type": "b", "children": [{"type": "t", "text": "GAS41 amplification results in overexpression of a new spindle pole protein."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes Chromosomes Cancer (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/gcc.21971"}], "href": "https://doi.org/10.1002/gcc.21971"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22619067"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22619067"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Chen Jixiang, Dang Shengchun, Qu Jianguo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "YEATS4 promotes the tumorigenesis of pancreatic cancer by activating beta-catenin/TCF signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncotarget (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/oncotarget.15633"}], "href": "https://doi.org/10.18632/oncotarget.15633"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28445953"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28445953"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Shilong Han, Chuanwu Cao, Rui Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "GAS41 mediates proliferation and GEM chemoresistance via H2A.Z.2 and Notch1 in pancreatic cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Oncol (Dordr) (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s13402-022-00675-8"}], "href": "https://doi.org/10.1007/s13402-022-00675-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35503594"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35503594"}]}]}]}
Synonyms	4930573H17RIK, NUBI-1, GAS41, B230215M10RIK, YAF9
Proteins	YETS4_HUMAN
NCBI Gene ID	8089
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

YEATS4 has 6,047 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 107 datasets.

Click the + buttons to view associations for YEATS4 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

YEATS4 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by YEATS4 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of YEATS4 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of YEATS4 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of YEATS4 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of YEATS4 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of YEATS4 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of YEATS4 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of YEATS4 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of YEATS4 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of YEATS4 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of YEATS4 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with YEATS4 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with YEATS4 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of YEATS4 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of YEATS4 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of YEATS4 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of YEATS4 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing YEATS4 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing YEATS4 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing YEATS4 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with YEATS4 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with YEATS4 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CORUM Protein Complexes	protein complexs containing YEATS4 protein from the CORUM Protein Complexes dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of YEATS4 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with YEATS4 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Disease Associations	diseases associated with YEATS4 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of YEATS4 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with YEATS4 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with YEATS4 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with YEATS4 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with YEATS4 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with YEATS4 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at YEATS4 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of YEATS4 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of YEATS4 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing YEATS4 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with YEATS4 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of YEATS4 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with YEATS4 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing YEATS4 from the GeneSigDB Published Gene Signatures dataset.