YOD1 Gene

HGNC Family	OTU domain containing (OTUD)
Name	YOD1 deubiquitinase
Description	Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. The protein encoded by this gene belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nYOD1 functions as a deubiquitinating enzyme central to cellular protein quality control and stress responses. It participates in the clearance of damaged endolysosomal compartments by selectively removing K48-linked ubiquitin chains downstream of K63-linked ubiquitination, thereby promoting autophagosome formation to eliminate compromised lysosomes."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Working in complex with the ATPase p97, YOD1 also facilitates the retro‐translocation and degradation of misfolded proteins in the endoplasmic reticulum, as evidenced by its essential role in ER-associated degradation (ERAD) that is highlighted by the accumulation of polyubiquitinated dislocation intermediates when its activity is impaired."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond protein quality control, YOD1 modulates several key signaling pathways. By interacting with TRAF6 and displacing its adaptor p62, YOD1 negatively regulates IL-1-driven NF-κB signaling."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": " In the innate antiviral response, YOD1 dampens signaling by cleaving K63-linked polyubiquitin chains on MAVS, thereby abrogating its prion-like aggregation necessary for full activation of IRF3 and NF-κB."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": " Moreover, YOD1 stabilizes the E3 ligase ITCH, which in turn mediates the ubiquitination and degradation of LATS kinases, culminating in increased YAP/TAZ activity, a key event in Hippo pathway modulation and cellular proliferation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": " Additionally, YOD1 restrains inflammasome activation by removing K33-linked ubiquitin chains from NLRP3, thereby mitigating excessive coagulation in sepsis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "8"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nYOD1 also plays emerging roles in development and tumorigenesis. In cervical cancer, its suppression by miR-373 correlates with enhanced cell proliferation, positioning YOD1 as a potential tumor suppressor."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": " Similarly, RNAi studies in models of nonsyndromic cleft lip with or without cleft palate and investigations in human oral keratinocytes underscore its importance in craniofacial development and epithelial cell migration and proliferation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "10"}]}, {"type": "t", "text": " Aberrant YOD1 expression is further implicated in tumor progression in triple-negative breast cancer"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "12"}]}, {"type": "t", "text": "and in liver cancer through Hippo pathway alterations, while its interaction with NEDD4 modulates α-synuclein stability in neurodegenerative contexts."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": " Finally, regulation of YOD1 by the long noncoding RNA TUG1 has been found to contribute to multiple myeloma progression."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Chrisovalantis Papadopoulos, Philipp Kirchner, Monika Bug, et al. "}, {"type": "b", "children": [{"type": "t", "text": "VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EMBO J (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.15252/embj.201695148"}], "href": "https://doi.org/10.15252/embj.201695148"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27753622"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27753622"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Robert Ernst, Britta Mueller, Hidde L Ploegh, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2009.09.016"}], "href": "https://doi.org/10.1016/j.molcel.2009.09.016"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19818707"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19818707"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Linda Sasset, Gianluca Petris, Francesca Cesaratto, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The VCP/p97 and YOD1 Proteins Have Different Substrate-dependent Activities in Endoplasmic Reticulum-associated Degradation (ERAD)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M115.656660"}], "href": "https://doi.org/10.1074/jbc.M115.656660"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26463207"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26463207"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Gisela Schimmack, Kenji Schorpp, Kerstin Kutzner, et al. "}, {"type": "b", "children": [{"type": "t", "text": "YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Elife (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7554/eLife.22416"}], "href": "https://doi.org/10.7554/eLife.22416"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28244869"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28244869"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Chang Liu, Shan Huang, Xuelin Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Otubain YOD1 Suppresses Aggregation and Activation of the Signaling Adaptor MAVS through Lys63-Linked Deubiquitination."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Immunol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4049/jimmunol.1800656"}], "href": "https://doi.org/10.4049/jimmunol.1800656"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30952814"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30952814"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Youngeun Kim, Wantae Kim, Yonghee Song, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1620306114"}], "href": "https://doi.org/10.1073/pnas.1620306114"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28416659"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28416659"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Youngeun Kim, Eek-Hoon Jho "}, {"type": "b", "children": [{"type": "t", "text": "Deubiquitinase YOD1: the potent activator of YAP in hepatomegaly and liver cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMB Rep (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.5483/bmbrep.2017.50.6.078"}], "href": "https://doi.org/10.5483/bmbrep.2017.50.6.078"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28502290"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28502290"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Chang Liu, Caihong Fan, Jia Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "YOD1 protects against MRSA sepsis-induced DIC through Lys33-linked deubiquitination of NLRP3."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Death Dis (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41419-024-06731-5"}], "href": "https://doi.org/10.1038/s41419-024-06731-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38789414"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38789414"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Luo-Qiao Wang, Yue Zhang, Huan Yan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MicroRNA-373 functions as an oncogene and targets YOD1 gene in cervical cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2015.02.138"}], "href": "https://doi.org/10.1016/j.bbrc.2015.02.138"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25747718"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25747718"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Xiao-Long Zhou, Gang Chen, Meng-Xue Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Targeting YOD1 by RNA Interference Inhibits Proliferation and Migration of Human Oral Keratinocytes through Transforming Growth Factor-"}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "β"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": "3 Signaling Pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biomed Res Int (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2018/6254308"}], "href": "https://doi.org/10.1155/2018/6254308"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30345304"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30345304"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Qiang Ju, Meng Xue Li, Gang Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Overexpression of YOD1 Promotes the Migration of Human Oral Keratinocytes by Enhancing TGF-β3 Signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biomed Environ Sci (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3967/bes2018.067"}], "href": "https://doi.org/10.3967/bes2018.067"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30145984"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30145984"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Zhitao Han, Qi Jia, Jing Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Deubiquitylase YOD1 regulates CDK1 stability and drives triple-negative breast cancer tumorigenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Exp Clin Cancer Res (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s13046-023-02781-3"}], "href": "https://doi.org/10.1186/s13046-023-02781-3"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37667382"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37667382"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Sang-Soo Park, Hyeon-Ah Do, Hong-Beom Park, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Deubiquitinating enzyme YOD1 deubiquitinates and destabilizes α-synuclein."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2023.01.030"}], "href": "https://doi.org/10.1016/j.bbrc.2023.01.030"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36682332"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36682332"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Qingqing Yin, Xianjuan Shen, Honglei Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "YY1-induced LncRNA-TUG1 elevates YOD1 to promote cell proliferation and inhibit bortezomib sensitivity in multiple myeloma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Leuk Lymphoma (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/10428194.2023.2200516"}], "href": "https://doi.org/10.1080/10428194.2023.2200516"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37078241"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37078241"}]}]}]}
Synonyms	DUBA8, OTUD2, PRO0907
Proteins	OTU1_HUMAN
NCBI Gene ID	55432
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

YOD1 has 5,490 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 111 datasets.

Click the + buttons to view associations for YOD1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

YOD1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of YOD1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of YOD1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of YOD1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of YOD1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of YOD1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of YOD1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of YOD1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of YOD1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of YOD1 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of YOD1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of YOD1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with YOD1 protein from the CCLE Cell Line Proteomics dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of YOD1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of YOD1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of YOD1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing YOD1 protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of YOD1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing YOD1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing YOD1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with YOD1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with YOD1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of YOD1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with YOD1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Disease Associations	diseases associated with YOD1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with YOD1 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of YOD1 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by YOD1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with YOD1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with YOD1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with YOD1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with YOD1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with YOD1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at YOD1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of YOD1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of YOD1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing YOD1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with YOD1 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of YOD1 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with YOD1 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing YOD1 from the GeneSigDB Published Gene Signatures dataset.