YWHAB Gene

Name	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
Description	This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nYWHAB, encoding the 14‐3‐3β isoform, is a multifunctional adapter protein that interacts with phosphorylated motifs on a wide range of signaling partners. Through binding to key regulators such as RSK1, it modulates kinase activity, cell cycle progression, cell migration, and anti‐apoptotic pathways. Its overexpression has been linked to oncogenic processes in diverse cancers—for example, colorectal, gastric, hepatocellular, and cervical—where it correlates with enhanced tumor invasiveness and resistance to apoptosis. Conversely, altered expression or regulation of YWHAB has been implicated in neuropsychiatric conditions."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "6"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its role in oncogenesis and cell survival, YWHAB is critically involved in metabolic and signal‐integration pathways. It enhances glucocorticoid receptor transactivation and hepatic gluconeogenesis while also fine‐tuning lipid metabolism via interactions with PPARγ. In epithelial cells, YWHAB binding promotes the biogenesis of chloride channels (CFTR), and its engagement with components of the Wnt pathway via Dapper1 underscores a role in developmental signaling. Additional interactions—involving proteins such as lipin 1 and sites on the insulin‐like growth factor receptor—further highlight its participation in regulating intracellular localization and vascular pathologies such as idiopathic pulmonary arterial hypertension."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "7", "end_ref": "13"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nMoreover, YWHAB plays important roles in neurological and infectious disease contexts. Its altered expression has been noted in conditions such as schizophrenia and neurodegeneration, where detection of 14‐3‐3β in cerebrospinal fluid serves as a potential biomarker. In glioblastoma models, diminished levels of YWHAB induce cellular senescence, highlighting its part in maintaining proliferative capacity. In addition, YWHAB is co‐opted by viral proteins to modulate pathogen budding and host responses, thereby contributing to infection biology. Collectively, these diverse functions designate YWHAB as a pivotal coordinator of signal transduction with widespread impact on cell survival, metabolism, and disease pathogenesis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "14", "end_ref": "20"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Megan E Cavet, Stephanie Lehoux, Bradford C Berk "}, {"type": "b", "children": [{"type": "t", "text": "14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M208475200"}], "href": "https://doi.org/10.1074/jbc.M208475200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12618428"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12618428"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Yufu Tang, Pengfei Lv, Zhongyi Sun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "14-3-3β Promotes Migration and Invasion of Human Hepatocellular Carcinoma Cells by Modulating Expression of MMP2 and MMP9 through PI3K/Akt/NF-κB Pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0146070"}], "href": "https://doi.org/10.1371/journal.pone.0146070"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26730736"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26730736"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Chien-Wei Tseng, Jyh-Chin Yang, Chiung-Nien Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of 14-3-3β in human gastric cancer cells and its potency as a diagnostic and prognostic biomarker."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proteomics (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/pmic.201000449"}], "href": "https://doi.org/10.1002/pmic.201000449"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21598387"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21598387"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Donna O'Dwyer, Lynda D Ralton, Aisling O'Shea, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The proteomics of colorectal cancer: identification of a protein signature associated with prognosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0027718"}], "href": "https://doi.org/10.1371/journal.pone.0027718"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22125622"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22125622"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Simon Jasinski-Bergner, Franziska Stehle, Evamaria Gonschorek, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of 14-3-3β gene as a novel miR-152 target using a proteome-based approach."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M114.556290"}], "href": "https://doi.org/10.1074/jbc.M114.556290"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25228695"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25228695"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Xia Zhang, Qing Zhang, Ke Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Circ SMARCA5 Inhibited Tumor Metastasis by Interacting with SND1 and Downregulating the YWHAB Gene in Cervical Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Transplant (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1177/0963689720983786"}], "href": "https://doi.org/10.1177/0963689720983786"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33588586"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33588586"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Yunhee Hwang, Hyoung-Tae An, Minsoo Kang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Roles of 14-3-3β and γ in regulation of the glucocorticoid receptor transcriptional activation and hepatic gluconeogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2018.05.077"}], "href": "https://doi.org/10.1016/j.bbrc.2018.05.077"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29772231"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29772231"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Sodam Park, Seungmin Yoo, Jeonghan Kim, et al. "}, {"type": "b", "children": [{"type": "t", "text": "14-3-3β and γ differentially regulate peroxisome proliferator activated receptor γ2 transactivation and hepatic lipid metabolism."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochim Biophys Acta (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbagrm.2015.08.002"}], "href": "https://doi.org/10.1016/j.bbagrm.2015.08.002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26260846"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26260846"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Xiubin Liang, Ana Carina Da Paula, Zoltán Bozóky, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Phosphorylation-dependent 14-3-3 protein interactions regulate CFTR biogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Biol Cell (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1091/mbc.E11-08-0662"}], "href": "https://doi.org/10.1091/mbc.E11-08-0662"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22278744"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22278744"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Hua Chen, Linhua Liu, Benyu Ma, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Protein kinase A-mediated 14-3-3 association impedes human Dapper1 to promote dishevelled degradation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M110.211607"}], "href": "https://doi.org/10.1074/jbc.M110.211607"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21262972"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21262972"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Tao Wang, Xuan Zheng, Ruidong Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Integrated bioinformatic analysis reveals YWHAB as a novel diagnostic biomarker for idiopathic pulmonary arterial hypertension."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Physiol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcp.27381"}], "href": "https://doi.org/10.1002/jcp.27381"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30317584"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30317584"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Meagan Hennessy, Mitchell E Granade, Azam Hassaninasab, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Casein kinase II-mediated phosphorylation of lipin 1β phosphatidate phosphatase at Ser-285 and Ser-287 regulates its interaction with 14-3-3β protein."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.RA118.007246"}], "href": "https://doi.org/10.1074/jbc.RA118.007246"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30617183"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30617183"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Susan Parvaresch, Tanju Yesilkaya, Kristin Baer, et al. "}, {"type": "b", "children": [{"type": "t", "text": "14-3-3 binding to the IGF-1 receptor is mediated by serine autophosphorylation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FEBS Lett (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0014-5793(02)03708-0"}], "href": "https://doi.org/10.1016/s0014-5793(02"}, {"type": "t", "text": "03708-0) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12482592"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12482592"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Frank A Middleton, Lansha Peng, David A Lewis, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Altered expression of 14-3-3 genes in the prefrontal cortex of subjects with schizophrenia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neuropsychopharmacology (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.npp.1300674"}], "href": "https://doi.org/10.1038/sj.npp.1300674"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15726117"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15726117"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Hung-Chin Tsai, Yen-Lin Huang, Yao-Shen Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "14-3-3β protein expression in eosinophilic meningitis caused by Angiostrongylus cantonensis infection."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Res Notes (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1756-0500-7-97"}], "href": "https://doi.org/10.1186/1756-0500-7-97"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24555778"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24555778"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Sung Bin Seo, Je-Jung Lee, Hye Hyeon Yun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "14-3-3β Depletion Drives a Senescence Program in Glioblastoma Cells Through the ERK/SKP2/p27 Pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Neurobiol (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s12035-017-0407-8"}], "href": "https://doi.org/10.1007/s12035-017-0407-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28116547"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28116547"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Luis G Rodriguez, Jun-Lin Guan "}, {"type": "b", "children": [{"type": "t", "text": "14-3-3 regulation of cell spreading and migration requires a functional amphipathic groove."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Physiol (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcp.20122"}], "href": "https://doi.org/10.1002/jcp.20122"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15389601"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15389601"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Tobias Karlberg, Peter Hornyak, Ana Filipa Pinto, et al. "}, {"type": "b", "children": [{"type": "t", "text": "14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-018-06194-1"}], "href": "https://doi.org/10.1038/s41467-018-06194-1"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30224724"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30224724"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Zifei Pei, Megan S Harrison, Anthony P Schmitt "}, {"type": "b", "children": [{"type": "t", "text": "Parainfluenza virus 5 m protein interaction with host protein 14-3-3 negatively affects virus particle formation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Virol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/JVI.02111-10"}], "href": "https://doi.org/10.1128/JVI.02111-10"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21147917"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21147917"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Nadine Sichtig, Steffi Silling, Gertrud Steger "}, {"type": "b", "children": [{"type": "t", "text": "Papillomavirus binding factor (PBF)-mediated inhibition of cell growth is regulated by 14-3-3beta."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Arch Biochem Biophys (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.abb.2007.04.017"}], "href": "https://doi.org/10.1016/j.abb.2007.04.017"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17531190"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17531190"}]}]}]}
Synonyms	GW128, HEL-S-1, KCIP-1, YWHAA
Proteins	1433B_HUMAN
NCBI Gene ID	7529
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

YWHAB has 10,571 functional associations with biological entities spanning 9 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 123 datasets.

Click the + buttons to view associations for YWHAB from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

YWHAB Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by YWHAB gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of YWHAB gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of YWHAB gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of YWHAB gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of YWHAB gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of YWHAB gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of YWHAB gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of YWHAB gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of YWHAB gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of YWHAB gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of YWHAB gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with YWHAB protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with YWHAB gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of YWHAB gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of YWHAB gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of YWHAB gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing YWHAB protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing YWHAB protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing YWHAB protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with YWHAB protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with YWHAB protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CORUM Protein Complexes	protein complexs containing YWHAB protein from the CORUM Protein Complexes dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of YWHAB gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with YWHAB gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with YWHAB gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with YWHAB gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of YWHAB protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by YWHAB gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with YWHAB gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with YWHAB gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with YWHAB gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with YWHAB gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with YWHAB gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at YWHAB gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of YWHAB gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of YWHAB gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing YWHAB from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with YWHAB gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with YWHAB gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of YWHAB gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.