(+/-)-catechin-4255 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the (+/-)-catechin-4255 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADGRB3 adhesion G protein-coupled receptor B3
ALOXE3 arachidonate lipoxygenase 3
AOC3 amine oxidase, copper containing 3
ARNT aryl hydrocarbon receptor nuclear translocator
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
BAAT bile acid CoA:amino acid N-acyltransferase
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BGN biglycan
BTBD18 BTB (POZ) domain containing 18
C11ORF21 chromosome 11 open reading frame 21
C17ORF53 chromosome 17 open reading frame 53
C17ORF59 chromosome 17 open reading frame 59
C18ORF25 chromosome 18 open reading frame 25
CADM1 cell adhesion molecule 1
CCDC57 coiled-coil domain containing 57
CD53 CD53 molecule
CDC14A cell division cycle 14A
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CFAP74 cilia and flagella associated protein 74
CLTB clathrin, light chain B
CNTN5 contactin 5
CNTNAP2 contactin associated protein-like 2
COL4A6 collagen, type IV, alpha 6
CORO1B coronin, actin binding protein, 1B
CORO2B coronin, actin binding protein, 2B
CTNS cystinosin, lysosomal cystine transporter
CXXC4 CXXC finger protein 4
CYSLTR1 cysteinyl leukotriene receptor 1
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DGKE diacylglycerol kinase, epsilon 64kDa
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
DTNA dystrobrevin, alpha
EDN3 endothelin 3
EDNRA endothelin receptor type A
EFR3B EFR3 homolog B (S. cerevisiae)
EXOSC2 exosome component 2
FAM149A family with sequence similarity 149, member A
FAXDC2 fatty acid hydroxylase domain containing 2
FGB fibrinogen beta chain
FGFR2 fibroblast growth factor receptor 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR63 G protein-coupled receptor 63
HABP2 hyaluronan binding protein 2
HEG1 heart development protein with EGF-like domains 1
IGLJ3 immunoglobulin lambda joining 3
IL36G interleukin 36, gamma
INE1 inactivation escape 1 (non-protein coding)
IPO8 importin 8
IRF5 interferon regulatory factor 5
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KAT6A K(lysine) acetyltransferase 6A
KIF25 kinesin family member 25
KRT32 keratin 32, type I
LAMB4 laminin, beta 4
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MBL2 mannose-binding lectin (protein C) 2, soluble
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MORN1 MORN repeat containing 1
MR1 major histocompatibility complex, class I-related
MYO9B myosin IXB
NNAT neuronatin
NR1H4 nuclear receptor subfamily 1, group H, member 4
NUP54 nucleoporin 54kDa
OR2J2 olfactory receptor, family 2, subfamily J, member 2
PAX5 paired box 5
PKNOX2 PBX/knotted 1 homeobox 2
PKP4 plakophilin 4
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXDC1 plexin domain containing 1
PODXL2 podocalyxin-like 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RETN resistin
RIN3 Ras and Rab interactor 3
SAFB scaffold attachment factor B
SAYSD1 SAYSVFN motif domain containing 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SOCS3 suppressor of cytokine signaling 3
SPARCL1 SPARC-like 1 (hevin)
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STMN3 stathmin-like 3
TENM1 teneurin transmembrane protein 1
TEX13A testis expressed 13A
THSD4 thrombospondin, type I, domain containing 4
TLK1 tousled-like kinase 1
TNIK TRAF2 and NCK interacting kinase
TRD T cell receptor delta locus
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSPAN2 tetraspanin 2
VPREB1 pre-B lymphocyte 1
WDR62 WD repeat domain 62
ZFHX2 zinc finger homeobox 2
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF141 zinc finger protein 141
ZNF219 zinc finger protein 219
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ADAM2 ADAM metallopeptidase domain 2
ADAM23 ADAM metallopeptidase domain 23
ADGRB2 adhesion G protein-coupled receptor B2
ALOX12 arachidonate 12-lipoxygenase
ANGPT4 angiopoietin 4
ANXA2P1 annexin A2 pseudogene 1
BBC3 BCL2 binding component 3
C2ORF54 chromosome 2 open reading frame 54
C7ORF69 chromosome 7 open reading frame 69
CAMKMT calmodulin-lysine N-methyltransferase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASS4 Cas scaffolding protein family member 4
CCDC85C coiled-coil domain containing 85C
CCP110 centriolar coiled coil protein 110kDa
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDH10 cadherin 10, type 2 (T2-cadherin)
CELP carboxyl ester lipase pseudogene
CFAP45 cilia and flagella associated protein 45
CIDEC cell death-inducing DFFA-like effector c
CLEC2B C-type lectin domain family 2, member B
CNGB3 cyclic nucleotide gated channel beta 3
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRLF1 cytokine receptor-like factor 1
CXCR2 chemokine (C-X-C motif) receptor 2
DDN dendrin
DMTN dematin actin binding protein
ENOX1 ecto-NOX disulfide-thiol exchanger 1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL15 F-box and leucine-rich repeat protein 15
FGF20 fibroblast growth factor 20
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLS2 glutaminase 2 (liver, mitochondrial)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR75 G protein-coupled receptor 75
GRM4 glutamate receptor, metabotropic 4
HINFP histone H4 transcription factor
HIST1H2AK histone cluster 1, H2ak
HIST1H2BO histone cluster 1, H2bo
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IER3IP1 immediate early response 3 interacting protein 1
IL2 interleukin 2
IMPG1 interphotoreceptor matrix proteoglycan 1
KANSL3 KAT8 regulatory NSL complex subunit 3
KLHL25 kelch-like family member 25
LENEP lens epithelial protein
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMO7 LIM domain 7
LOC729164 hCG1732469
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LRRC61 leucine rich repeat containing 61
LTC4S leukotriene C4 synthase
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MBTPS2 membrane-bound transcription factor peptidase, site 2
MTERF4 mitochondrial transcription termination factor 4
MYH15 myosin, heavy chain 15
MYO15A myosin XVA
NDP Norrie disease (pseudoglioma)
NOTCH4 notch 4
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PIP prolactin-induced protein
PLSCR2 phospholipid scramblase 2
PMCH pro-melanin-concentrating hormone
PRKG2 protein kinase, cGMP-dependent, type II
PRSS50 protease, serine, 50
PTPRS protein tyrosine phosphatase, receptor type, S
QSER1 glutamine and serine rich 1
RAB3A RAB3A, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RFPL1 ret finger protein-like 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A3 S100 calcium binding protein A3
SCEL sciellin
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIX3 SIX homeobox 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SSBP3 single stranded DNA binding protein 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP4 STEAP family member 4
STRN striatin, calmodulin binding protein
SYNGR3 synaptogyrin 3
TBKBP1 TBK1 binding protein 1
TMEM212 transmembrane protein 212
TOM1 target of myb1 (chicken)
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
VGF VGF nerve growth factor inducible
WNT1 wingless-type MMTV integration site family, member 1
ZBTB22 zinc finger and BTB domain containing 22
ZNF140 zinc finger protein 140
ZNF480 zinc finger protein 480
ZNF675 zinc finger protein 675
ZNF749 zinc finger protein 749