(+)-chelidonine-5760 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the (+)-chelidonine-5760 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADD2 adducin 2 (beta)
AKAP5 A kinase (PRKA) anchor protein 5
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APP amyloid beta (A4) precursor protein
ARMC8 armadillo repeat containing 8
ATAD5 ATPase family, AAA domain containing 5
ATF7IP2 activating transcription factor 7 interacting protein 2
C10ORF12 chromosome 10 open reading frame 12
C1ORF95 chromosome 1 open reading frame 95
C1QB complement component 1, q subcomponent, B chain
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CA5B carbonic anhydrase VB, mitochondrial
CDH10 cadherin 10, type 2 (T2-cadherin)
CDHR2 cadherin-related family member 2
CLCN7 chloride channel, voltage-sensitive 7
CLDN1 claudin 1
COPS8 COP9 signalosome subunit 8
CRMP1 collapsin response mediator protein 1
CROCC ciliary rootlet coiled-coil, rootletin
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DNAI2 dynein, axonemal, intermediate chain 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP1 dual specificity phosphatase 1
EGR2 early growth response 2
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
FAM188A family with sequence similarity 188, member A
FGF5 fibroblast growth factor 5
FNDC3A fibronectin type III domain containing 3A
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GBP1 guanylate binding protein 1, interferon-inducible
GK3P glycerol kinase 3 pseudogene
GRIA3 glutamate receptor, ionotropic, AMPA 3
HBEGF heparin-binding EGF-like growth factor
HEG1 heart development protein with EGF-like domains 1
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HOXB3 homeobox B3
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ING4 inhibitor of growth family, member 4
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INSR insulin receptor
JAK2 Janus kinase 2
JUND jun D proto-oncogene
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0319L KIAA0319-like
KIAA1109 KIAA1109
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KRT34 keratin 34, type I
KRT6A keratin 6A, type II
MCF2L MCF.2 cell line derived transforming sequence-like
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED16 mediator complex subunit 16
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MKL1 megakaryoblastic leukemia (translocation) 1
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
NF1 neurofibromin 1
NUP210 nucleoporin 210kDa
PAWR PRKC, apoptosis, WT1, regulator
PDCD2 programmed cell death 2
PDE12 phosphodiesterase 12
PEX7 peroxisomal biogenesis factor 7
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLXNC1 plexin C1
PPARD peroxisome proliferator-activated receptor delta
PRDM14 PR domain containing 14
PTGDR2 prostaglandin D2 receptor 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRR protein tyrosine phosphatase, receptor type, R
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RGS12 regulator of G-protein signaling 12
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RRH retinal pigment epithelium-derived rhodopsin homolog
RUNX1 runt-related transcription factor 1
SAFB scaffold attachment factor B
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLIT1 slit homolog 1 (Drosophila)
SMC1A structural maintenance of chromosomes 1A
SNAP23 synaptosomal-associated protein, 23kDa
SOCS3 suppressor of cytokine signaling 3
SOGA1 suppressor of glucose, autophagy associated 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYT17 synaptotagmin XVII
TGFA transforming growth factor, alpha
TGFB2 transforming growth factor, beta 2
TSPAN9 tetraspanin 9
TTC39A tetratricopeptide repeat domain 39A
U2SURP U2 snRNP-associated SURP domain containing
ZER1 zyg-11 related, cell cycle regulator
ZFX zinc finger protein, X-linked

decreased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ARHGAP22 Rho GTPase activating protein 22
ASAP1-IT1 ASAP1 intronic transcript 1
ASIC3 acid sensing (proton gated) ion channel 3
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
C1ORF56 chromosome 1 open reading frame 56
C5ORF45 chromosome 5 open reading frame 45
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK3 cyclin-dependent kinase 3
CEMIP cell migration inducing protein, hyaluronan binding
CENPO centromere protein O
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRY2 cryptochrome circadian clock 2
CRYBA2 crystallin, beta A2
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DRP2 dystrophin related protein 2
DSPP dentin sialophosphoprotein
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EFNB1 ephrin-B1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM186A family with sequence similarity 186, member A
FAM50B family with sequence similarity 50, member B
FBXW12 F-box and WD repeat domain containing 12
FGL1 fibrinogen-like 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GJA9 gap junction protein, alpha 9, 59kDa
GLB1L2 galactosidase, beta 1-like 2
GLS2 glutaminase 2 (liver, mitochondrial)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GRM6 glutamate receptor, metabotropic 6
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HHLA3 HERV-H LTR-associating 3
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H2AC histone cluster 1, H2ac
HIST1H2BG histone cluster 1, H2bg
HIST1H2BI histone cluster 1, H2bi
HIST1H3C histone cluster 1, H3c
HIST2H2BE histone cluster 2, H2be
HIST3H2A histone cluster 3, H2a
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HOXA6 homeobox A6
HOXB5 homeobox B5
HOXC5 homeobox C5
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KCTD17 potassium channel tetramerization domain containing 17
KRT9 keratin 9, type I
LPAR3 lysophosphatidic acid receptor 3
LRRC17 leucine rich repeat containing 17
LRRC61 leucine rich repeat containing 61
LYPD3 LY6/PLAUR domain containing 3
MAGEH1 melanoma antigen family H1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MYLIP myosin regulatory light chain interacting protein
MYOZ3 myozenin 3
NDP Norrie disease (pseudoglioma)
NOD1 nucleotide-binding oligomerization domain containing 1
NPFFR1 neuropeptide FF receptor 1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NT5M 5',3'-nucleotidase, mitochondrial
NTSR1 neurotensin receptor 1 (high affinity)
NYNRIN NYN domain and retroviral integrase containing
ODF2 outer dense fiber of sperm tails 2
PBX3 pre-B-cell leukemia homeobox 3
PCOLCE procollagen C-endopeptidase enhancer
PENK proenkephalin
PLAG1 pleiomorphic adenoma gene 1
POM121 POM121 transmembrane nucleoporin
PRAMEF11 PRAME family member 11
PRR7 proline rich 7 (synaptic)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
SCARA3 scavenger receptor class A, member 3
SCGB2A2 secretoglobin, family 2A, member 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SETD6 SET domain containing 6
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAOK1 TAO kinase 1
TUBA1A tubulin, alpha 1a
TUBA3D tubulin, alpha 3d
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TXK TXK tyrosine kinase
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
ZFHX2 zinc finger homeobox 2
ZNF253 zinc finger protein 253
ZNF276 zinc finger protein 276
ZNF668 zinc finger protein 668