(+)-isoprenaline-3046 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the (+)-isoprenaline-3046 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY10 adenylate cyclase 10 (soluble)
AIM1L absent in melanoma 1-like
ANG angiogenin, ribonuclease, RNase A family, 5
ANK2 ankyrin 2, neuronal
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
AXL AXL receptor tyrosine kinase
BCAS3 breast carcinoma amplified sequence 3
BCAS4 breast carcinoma amplified sequence 4
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
C16ORF45 chromosome 16 open reading frame 45
C6ORF10 chromosome 6 open reading frame 10
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CALD1 caldesmon 1
CASR calcium-sensing receptor
CCDC70 coiled-coil domain containing 70
CD22 CD22 molecule
CD38 CD38 molecule
CD59 CD59 molecule, complement regulatory protein
CD72 CD72 molecule
CD86 CD86 molecule
CDK19 cyclin-dependent kinase 19
CHN2 chimerin 2
COL5A1 collagen, type V, alpha 1
COL9A3 collagen, type IX, alpha 3
CREM cAMP responsive element modulator
DOCK4 dedicator of cytokinesis 4
DPEP2 dipeptidase 2
DUSP4 dual specificity phosphatase 4
EGR4 early growth response 4
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FADS3 fatty acid desaturase 3
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GABARAPL1 GABA(A) receptor-associated protein like 1
GAS8 growth arrest-specific 8
GK3P glycerol kinase 3 pseudogene
GSTT1 glutathione S-transferase theta 1
HIST1H2AL histone cluster 1, H2al
HLA-DRA major histocompatibility complex, class II, DR alpha
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFNA6 interferon, alpha 6
IGLV3-19 immunoglobulin lambda variable 3-19
IL24 interleukin 24
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIAA1109 KIAA1109
KYNU kynureninase
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMB3 laminin, beta 3
LMOD1 leiomodin 1 (smooth muscle)
MAPK7 mitogen-activated protein kinase 7
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MYH14 myosin, heavy chain 14, non-muscle
N4BP2L2 NEDD4 binding protein 2-like 2
NID2 nidogen 2 (osteonidogen)
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRAP nebulin-related anchoring protein
NRG1 neuregulin 1
NT5E 5'-nucleotidase, ecto (CD73)
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
PCDHB17P protocadherin beta 17 pseudogene
PCLO piccolo presynaptic cytomatrix protein
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PKP1 plakophilin 1
PLSCR1 phospholipid scramblase 1
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PRO2964 uncharacterized protein PRO2964
RASAL1 RAS protein activator like 1 (GAP1 like)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RGS12 regulator of G-protein signaling 12
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RUNDC3A RUN domain containing 3A
SCARB2 scavenger receptor class B, member 2
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SDC2 syndecan 2
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SFRP5 secreted frizzled-related protein 5
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SRPX2 sushi-repeat containing protein, X-linked 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUSD5 sushi domain containing 5
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAAR5 trace amine associated receptor 5
TAT tyrosine aminotransferase
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TCP10 t-complex 10
THBS1 thrombospondin 1
TIMELESS timeless circadian clock
TIMP1 TIMP metallopeptidase inhibitor 1
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNP2 transition protein 2 (during histone to protamine replacement)
TRAF1 TNF receptor-associated factor 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TYMP thymidine phosphorylase
ZNF137P zinc finger protein 137, pseudogene

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
AIM2 absent in melanoma 2
ALS2CL ALS2 C-terminal like
ANKRD55 ankyrin repeat domain 55
ASAP1-IT1 ASAP1 intronic transcript 1
ATXN2L ataxin 2-like
BATF3 basic leucine zipper transcription factor, ATF-like 3
BHLHE41 basic helix-loop-helix family, member e41
BIK BCL2-interacting killer (apoptosis-inducing)
C9ORF91 chromosome 9 open reading frame 91
CD320 CD320 molecule
CD34 CD34 molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CELP carboxyl ester lipase pseudogene
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTH cystathionine gamma-lyase
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDN dendrin
DEPTOR DEP domain containing MTOR-interacting protein
DUSP8 dual specificity phosphatase 8
ERCC2 excision repair cross-complementation group 2
EXO5 exonuclease 5
FAM86B1 family with sequence similarity 86, member B1
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FJX1 four jointed box 1 (Drosophila)
FKBP4 FK506 binding protein 4, 59kDa
FRS3 fibroblast growth factor receptor substrate 3
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GATA4 GATA binding protein 4
GCH1 GTP cyclohydrolase 1
GID4 GID complex subunit 4
GRIP2 glutamate receptor interacting protein 2
HIST1H1B histone cluster 1, H1b
HYAL2 hyaluronoglucosaminidase 2
IBSP integrin-binding sialoprotein
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
JAG2 jagged 2
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KLF3 Kruppel-like factor 3 (basic)
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LY75 lymphocyte antigen 75
MAK16 MAK16 homolog (S. cerevisiae)
METRN meteorin, glial cell differentiation regulator
MREG melanoregulin
MYO15A myosin XVA
NCS1 neuronal calcium sensor 1
NOL10 nucleolar protein 10
NR1D2 nuclear receptor subfamily 1, group D, member 2
OCLN occludin
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PADI2 peptidyl arginine deiminase, type II
PARP3 poly (ADP-ribose) polymerase family, member 3
PBOV1 prostate and breast cancer overexpressed 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCOLCE2 procollagen C-endopeptidase enhancer 2
PER3 period circadian clock 3
PFKM phosphofructokinase, muscle
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PMFBP1 polyamine modulated factor 1 binding protein 1
POMZP3 POM121 and ZP3 fusion
PRB3 proline-rich protein BstNI subfamily 3
PRICKLE3 prickle homolog 3 (Drosophila)
PSAT1 phosphoserine aminotransferase 1
RAB3A RAB3A, member RAS oncogene family
REC8 REC8 meiotic recombination protein
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHOB ras homolog family member B
RPL23AP53 ribosomal protein L23a pseudogene 53
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SCARB1 scavenger receptor class B, member 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC12A9 solute carrier family 12, member 9
SLC35F5 solute carrier family 35, member F5
SOX12 SRY (sex determining region Y)-box 12
SPATA20 spermatogenesis associated 20
SPATA2L spermatogenesis associated 2-like
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SYTL2 synaptotagmin-like 2
TEC tec protein tyrosine kinase
TERT telomerase reverse transcriptase
TMEM53 transmembrane protein 53
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR18 WD repeat domain 18
YOD1 YOD1 deubiquitinase
ZNF215 zinc finger protein 215
ZNF225 zinc finger protein 225
ZNF721 zinc finger protein 721
ZNF749 zinc finger protein 749
ZNF768 zinc finger protein 768