(+)-isoprenaline-3384 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the (+)-isoprenaline-3384 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADCK2 aarF domain containing kinase 2
AGXT alanine-glyoxylate aminotransferase
ARHGAP4 Rho GTPase activating protein 4
BDKRB2 bradykinin receptor B2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C18ORF25 chromosome 18 open reading frame 25
C3ORF18 chromosome 3 open reading frame 18
CALCR calcitonin receptor
CCL13 chemokine (C-C motif) ligand 13
CCRL2 chemokine (C-C motif) receptor-like 2
CD80 CD80 molecule
CEP41 centrosomal protein 41kDa
CFAP45 cilia and flagella associated protein 45
CFAP69 cilia and flagella associated protein 69
CFHR4 complement factor H-related 4
CLTA clathrin, light chain A
COL3A1 collagen, type III, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTGF connective tissue growth factor
CXCR4 chemokine (C-X-C motif) receptor 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK2 death-associated protein kinase 2
DCBLD2 discoidin, CUB and LCCL domain containing 2
DGCR8 DGCR8 microprocessor complex subunit
DGKE diacylglycerol kinase, epsilon 64kDa
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DOPEY2 dopey family member 2
EDA ectodysplasin A
EPN1 epsin 1
ERO1LB ERO1-like beta (S. cerevisiae)
EXOC6B exocyst complex component 6B
FAM110B family with sequence similarity 110, member B
FGF22 fibroblast growth factor 22
FGF5 fibroblast growth factor 5
FGFR3 fibroblast growth factor receptor 3
FRMD1 FERM domain containing 1
FXYD5 FXYD domain containing ion transport regulator 5
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HFE hemochromatosis
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ICOSLG inducible T-cell co-stimulator ligand
INA internexin neuronal intermediate filament protein, alpha
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KRT16 keratin 16, type I
LTBP2 latent transforming growth factor beta binding protein 2
MCAM melanoma cell adhesion molecule
MYCNOS MYCN opposite strand
MYOF myoferlin
NDRG2 NDRG family member 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEU3 sialidase 3 (membrane sialidase)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NPY2R neuropeptide Y receptor Y2
NR6A1 nuclear receptor subfamily 6, group A, member 1
OAZ3 ornithine decarboxylase antizyme 3
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PEG10 paternally expressed 10
PLD1 phospholipase D1, phosphatidylcholine-specific
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PVR poliovirus receptor
RAB40C RAB40C, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RGS14 regulator of G-protein signaling 14
RNF122 ring finger protein 122
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPS4Y1 ribosomal protein S4, Y-linked 1
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SETBP1 SET binding protein 1
SFTPC surfactant protein C
SH2D3A SH2 domain containing 3A
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SSX1 synovial sarcoma, X breakpoint 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT4 signal transducer and activator of transcription 4
SULT4A1 sulfotransferase family 4A, member 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYNDIG1 synapse differentiation inducing 1
SYT2 synaptotagmin II
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAT tyrosine aminotransferase
TBX5 T-box 5
TMOD2 tropomodulin 2 (neuronal)
TPSG1 tryptase gamma 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRBC1 T cell receptor beta constant 1
TSPAN32 tetraspanin 32
TYRO3 TYRO3 protein tyrosine kinase
UMPS uridine monophosphate synthetase
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VGLL1 vestigial-like family member 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZFAND5 zinc finger, AN1-type domain 5
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACTL8 actin-like 8
ALPK1 alpha-kinase 1
AMH anti-Mullerian hormone
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ATAT1 alpha tubulin acetyltransferase 1
AUTS2 autism susceptibility candidate 2
BMP4 bone morphogenetic protein 4
C3 complement component 3
CAMTA2 calmodulin binding transcription activator 2
CDKN2AIP CDKN2A interacting protein
CENPO centromere protein O
CIC capicua transcriptional repressor
CLCN6 chloride channel, voltage-sensitive 6
CLGN calmegin
CNTNAP1 contactin associated protein 1
CPA4 carboxypeptidase A4
CPTP ceramide-1-phosphate transfer protein
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DBF4B DBF4 zinc finger B
DEAF1 DEAF1 transcription factor
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DUSP2 dual specificity phosphatase 2
DYSF dysferlin
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC5 excision repair cross-complementation group 5
FAM184A family with sequence similarity 184, member A
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GAMT guanidinoacetate N-methyltransferase
GPR143 G protein-coupled receptor 143
GPR157 G protein-coupled receptor 157
GRAMD1C GRAM domain containing 1C
GSTTP1 glutathione S-transferase theta pseudogene 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AI histone cluster 1, H2ai
HOXC8 homeobox C8
ICK intestinal cell (MAK-like) kinase
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCTD17 potassium channel tetramerization domain containing 17
KCTD7 potassium channel tetramerization domain containing 7
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KIAA0355 KIAA0355
LHX1 LIM homeobox 1
LOXL3 lysyl oxidase-like 3
LYRM9 LYR motif containing 9
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGEA5 melanoma antigen family A5
MAPK10 mitogen-activated protein kinase 10
MCOLN3 mucolipin 3
MFGE8 milk fat globule-EGF factor 8 protein
MMP2 matrix metallopeptidase 2
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NEUROD4 neuronal differentiation 4
NLRX1 NLR family member X1
NME5 NME/NM23 family member 5
NOL10 nucleolar protein 10
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPY1R neuropeptide Y receptor Y1
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PADI1 peptidyl arginine deiminase, type I
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLTP phospholipid transfer protein
PLXNB3 plexin B3
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB40AL RAB40A, member RAS oncogene family-like
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIN2 Ras and Rab interactor 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SETD1A SET domain containing 1A
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLPI secretory leukocyte peptidase inhibitor
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNX15 sorting nexin 15
SPRY2 sprouty homolog 2 (Drosophila)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STIM1 stromal interaction molecule 1
SUSD6 sushi domain containing 6
TBC1D2 TBC1 domain family, member 2
TBKBP1 TBK1 binding protein 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THRAP3 thyroid hormone receptor associated protein 3
TMEM254 transmembrane protein 254
TMEM45A transmembrane protein 45A
TMEM53 transmembrane protein 53
USP27X ubiquitin specific peptidase 27, X-linked
ZFHX4 zinc finger homeobox 4
ZFP37 ZFP37 zinc finger protein
ZNF230 zinc finger protein 230
ZNF442 zinc finger protein 442
ZNF552 zinc finger protein 552
ZNF669 zinc finger protein 669
ZNF750 zinc finger protein 750