(+)-isoprenaline-5009 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the (+)-isoprenaline-5009 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAM22 ADAM metallopeptidase domain 22
ADAM23 ADAM metallopeptidase domain 23
ADAP2 ArfGAP with dual PH domains 2
ADRA1D adrenoceptor alpha 1D
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AQP4 aquaporin 4
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARPIN actin-related protein 2/3 complex inhibitor
BICD1 bicaudal D homolog 1 (Drosophila)
BTN2A1 butyrophilin, subfamily 2, member A1
C10ORF95 chromosome 10 open reading frame 95
C7ORF69 chromosome 7 open reading frame 69
CA11 carbonic anhydrase XI
CALML5 calmodulin-like 5
CD248 CD248 molecule, endosialin
CD300A CD300a molecule
CD36 CD36 molecule (thrombospondin receptor)
CLCN7 chloride channel, voltage-sensitive 7
CLTC clathrin, heavy chain (Hc)
COL6A1 collagen, type VI, alpha 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSTA cystatin A (stefin A)
CUL7 cullin 7
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK4 docking protein 4
EFNB3 ephrin-B3
EMC3 ER membrane protein complex subunit 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHB2 EPH receptor B2
FAM155B family with sequence similarity 155, member B
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GK glycerol kinase
GPR153 G protein-coupled receptor 153
GYG2 glycogenin 2
HABP2 hyaluronan binding protein 2
HIST1H4F histone cluster 1, H4f
HNF4A hepatocyte nuclear factor 4, alpha
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ING4 inhibitor of growth family, member 4
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLK3 kallikrein-related peptidase 3
KRT15 keratin 15, type I
KRT2 keratin 2, type II
LIF leukemia inhibitory factor
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPK13 mitogen-activated protein kinase 13
MAST3 microtubule associated serine/threonine kinase 3
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MOCS1 molybdenum cofactor synthesis 1
MRPL41 mitochondrial ribosomal protein L41
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAT6 N-acetyltransferase 6 (GCN5-related)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NNAT neuronatin
NOL12 nucleolar protein 12
NR2F6 nuclear receptor subfamily 2, group F, member 6
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OSBP2 oxysterol binding protein 2
OSBPL10 oxysterol binding protein-like 10
PARD6A par-6 family cell polarity regulator alpha
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRU protein tyrosine phosphatase, receptor type, U
QPCTL glutaminyl-peptide cyclotransferase-like
RAD51D RAD51 paralog D
RFPL3 ret finger protein-like 3
S100A8 S100 calcium binding protein A8
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLIT1 slit homolog 1 (Drosophila)
SMIM14 small integral membrane protein 14
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAB2 stabilin 2
STC1 stanniocalcin 1
SYNJ2 synaptojanin 2
SZT2 seizure threshold 2 homolog (mouse)
TBL2 transducin (beta)-like 2
TNK1 tyrosine kinase, non-receptor, 1
TRIB2 tribbles pseudokinase 2
TRIO trio Rho guanine nucleotide exchange factor
TSPAN9 tetraspanin 9
TTC38 tetratricopeptide repeat domain 38
TTLL3 tubulin tyrosine ligase-like family member 3
VAC14 Vac14 homolog (S. cerevisiae)
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADCY6 adenylate cyclase 6
ALOX15 arachidonate 15-lipoxygenase
ALPK1 alpha-kinase 1
ARRB1 arrestin, beta 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BGLAP bone gamma-carboxyglutamate (gla) protein
C17ORF80 chromosome 17 open reading frame 80
C5ORF45 chromosome 5 open reading frame 45
C8ORF60 chromosome 8 open reading frame 60
C9ORF40 chromosome 9 open reading frame 40
CA5BP1 carbonic anhydrase VB pseudogene 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC130 coiled-coil domain containing 130
CCDC88C coiled-coil domain containing 88C
CD83 CD83 molecule
CDK20 cyclin-dependent kinase 20
CEP97 centrosomal protein 97kDa
CES3 carboxylesterase 3
CLCF1 cardiotrophin-like cytokine factor 1
CNGB3 cyclic nucleotide gated channel beta 3
CORO7 coronin 7
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRIP1 cysteine-rich protein 1 (intestinal)
CSF1R colony stimulating factor 1 receptor
CST6 cystatin E/M
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DMC1 DNA meiotic recombinase 1
DNAL4 dynein, axonemal, light chain 4
ELMO3 engulfment and cell motility 3
FRMD1 FERM domain containing 1
FUZ fuzzy planar cell polarity protein
GLS2 glutaminase 2 (liver, mitochondrial)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG3 guanine nucleotide binding protein (G protein), gamma 3
HIST1H2AJ histone cluster 1, H2aj
HLA-J major histocompatibility complex, class I, J (pseudogene)
IFT54 intraflagellar transport 54
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0894 KIAA0894 protein
KLF3 Kruppel-like factor 3 (basic)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LOC729164 hCG1732469
LRRC37A3 leucine rich repeat containing 37, member A3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NME5 NME/NM23 family member 5
NPR3 natriuretic peptide receptor 3
NRSN2 neurensin 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDHGB5 protocadherin gamma subfamily B, 5
PLA2G15 phospholipase A2, group XV
PLCD1 phospholipase C, delta 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
POMT2 protein-O-mannosyltransferase 2
PRF1 perforin 1 (pore forming protein)
PRSS22 protease, serine, 22
PTPN14 protein tyrosine phosphatase, non-receptor type 14
QSER1 glutamine and serine rich 1
RAB30 RAB30, member RAS oncogene family
RNF122 ring finger protein 122
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
S100A2 S100 calcium binding protein A2
SALL2 spalt-like transcription factor 2
SDC3 syndecan 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SH2B3 SH2B adaptor protein 3
SLC35F6 solute carrier family 35, member F6
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLN sarcolipin
SPINK5 serine peptidase inhibitor, Kazal type 5
SRD5A3 steroid 5 alpha-reductase 3
SYT17 synaptotagmin XVII
TCTN2 tectonic family member 2
TDRD1 tudor domain containing 1
TEX40 testis expressed 40
TGFBR3 transforming growth factor, beta receptor III
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM21 tripartite motif containing 21
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA4B tubulin, alpha 4b
UBXN6 UBX domain protein 6
VASH1 vasohibin 1
VAV1 vav 1 guanine nucleotide exchange factor
VEGFC vascular endothelial growth factor C
VGF VGF nerve growth factor inducible
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF16 zinc finger protein 16
ZNF510 zinc finger protein 510