| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (-)-MK-801-5003 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADCY2 | adenylate cyclase 2 (brain) |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AK1 | adenylate kinase 1 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| APOL6 | apolipoprotein L, 6 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BAX | BCL2-associated X protein |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BTG2 | BTG family, member 2 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C6 | complement component 6 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD58 | CD58 molecule |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTGF | connective tissue growth factor |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DUSP13 | dual specificity phosphatase 13 |
| EMID1 | EMI domain containing 1 |
| EPHB2 | EPH receptor B2 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM46C | family with sequence similarity 46, member C |
| FBN1 | fibrillin 1 |
| FCAR | Fc fragment of IgA receptor |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FGF13 | fibroblast growth factor 13 |
| FGF18 | fibroblast growth factor 18 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GK | glycerol kinase |
| GLB1L | galactosidase, beta 1-like |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HMOX1 | heme oxygenase 1 |
| HPX | hemopexin |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNA17 | interferon, alpha 17 |
| ING1 | inhibitor of growth family, member 1 |
| INHBA | inhibin, beta A |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| IRF8 | interferon regulatory factor 8 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KRT24 | keratin 24, type I |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMF2 | lipase maturation factor 2 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MMP13 | matrix metallopeptidase 13 |
| MMP3 | matrix metallopeptidase 3 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MYOD1 | myogenic differentiation 1 |
| NKX6-1 | NK6 homeobox 1 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| PDCD2 | programmed cell death 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RASAL2 | RAS protein activator like 2 |
| RGS20 | regulator of G-protein signaling 20 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| S100B | S100 calcium binding protein B |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SFRP5 | secreted frizzled-related protein 5 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| STEAP4 | STEAP family member 4 |
| SVIL | supervillin |
| TAF7L | TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa |
| TESC | tescalcin |
| TMEM176A | transmembrane protein 176A |
| TPMT | thiopurine S-methyltransferase |
| TRD | T cell receptor delta locus |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VEGFB | vascular endothelial growth factor B |
| VN1R1 | vomeronasal 1 receptor 1 |
| VNN2 | vanin 2 |
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APIP | APAF1 interacting protein |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ATP11B | ATPase, class VI, type 11B |
| BAG4 | BCL2-associated athanogene 4 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CDC37 | cell division cycle 37 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLSPN | claspin |
| CNPY3 | canopy FGF signaling regulator 3 |
| COL9A2 | collagen, type IX, alpha 2 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DCPS | decapping enzyme, scavenger |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EFNA3 | ephrin-A3 |
| FAM127B | family with sequence similarity 127, member B |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FOXC1 | forkhead box C1 |
| GALK1 | galactokinase 1 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KLC2 | kinesin light chain 2 |
| LMBR1L | limb development membrane protein 1-like |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC49 | leucine rich repeat containing 49 |
| MBTD1 | mbt domain containing 1 |
| MGC12488 | |
| MOSPD3 | motile sperm domain containing 3 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXD3 | MAX dimerization protein 3 |
| N4BP3 | NEDD4 binding protein 3 |
| NBEAL2 | neurobeachin-like 2 |
| NEO1 | neogenin 1 |
| NME5 | NME/NM23 family member 5 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHGDH | phosphoglycerate dehydrogenase |
| PITX2 | paired-like homeodomain 2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| POMT2 | protein-O-mannosyltransferase 2 |
| PTK6 | protein tyrosine kinase 6 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPGRIP1L | RPGRIP1-like |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| SCRN3 | secernin 3 |
| SIK1 | salt-inducible kinase 1 |
| SIRAL2 | SIR2 antiphage like 2 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SPRYD7 | SPRY domain containing 7 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SRPX | sushi-repeat containing protein, X-linked |
| STRN4 | striatin, calmodulin binding protein 4 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TESK1 | testis-specific kinase 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM132A | transmembrane protein 132A |
| TMEM134 | transmembrane protein 134 |
| TMEM180 | transmembrane protein 180 |
| TMEM62 | transmembrane protein 62 |
| TRAF2 | TNF receptor-associated factor 2 |
| TSPYL2 | TSPY-like 2 |
| UCKL1 | uridine-cytidine kinase 1-like 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF286A | zinc finger protein 286A |
| ZNF34 | zinc finger protein 34 |
| ZNF350 | zinc finger protein 350 |
| ZNF492 | zinc finger protein 492 |
| ZNF668 | zinc finger protein 668 |
| ZNF74 | zinc finger protein 74 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
