| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the (-)-atenolol-5325 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| APC | adenomatous polyposis coli |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ARHGAP17 | Rho GTPase activating protein 17 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| B4GALT7 | xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BMP4 | bone morphogenetic protein 4 |
| BTBD7 | BTB (POZ) domain containing 7 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CCDC69 | coiled-coil domain containing 69 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CPTP | ceramide-1-phosphate transfer protein |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DSCAM | Down syndrome cell adhesion molecule |
| DSPP | dentin sialophosphoprotein |
| DTNA | dystrobrevin, alpha |
| EDAR | ectodysplasin A receptor |
| FAM188A | family with sequence similarity 188, member A |
| FAM46C | family with sequence similarity 46, member C |
| FBXO31 | F-box protein 31 |
| FBXO38 | F-box protein 38 |
| FLJ11292 | |
| FMOD | fibromodulin |
| FNDC3A | fibronectin type III domain containing 3A |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FSCN1 | fascin actin-bundling protein 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GSTM1 | glutathione S-transferase mu 1 |
| HFE | hemochromatosis |
| HIST1H2AJ | histone cluster 1, H2aj |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| HSF2 | heat shock transcription factor 2 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFT38 | intraflagellar transport 38 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MDM4 | MDM4, p53 regulator |
| MECP2 | methyl CpG binding protein 2 |
| MPPE1 | metallophosphoesterase 1 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MZF1 | myeloid zinc finger 1 |
| N4BP1 | NEDD4 binding protein 1 |
| NEK1 | NIMA-related kinase 1 |
| NFYA | nuclear transcription factor Y, alpha |
| NIPAL2 | NIPA-like domain containing 2 |
| NOTCH2 | notch 2 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| OSMR | oncostatin M receptor |
| PDCD2 | programmed cell death 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE8B | phosphodiesterase 8B |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLA2G10 | phospholipase A2, group X |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POFUT1 | protein O-fucosyltransferase 1 |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB6A | RAB6A, member RAS oncogene family |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| S100A7 | S100 calcium binding protein A7 |
| S100A9 | S100 calcium binding protein A9 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SH3BP2 | SH3-domain binding protein 2 |
| SHPK | sedoheptulokinase |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SSH1 | slingshot protein phosphatase 1 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TMOD1 | tropomodulin 1 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRBC1 | T cell receptor beta constant 1 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUSC2 | tumor suppressor candidate 2 |
| UPF1 | UPF1 regulator of nonsense transcripts homolog (yeast) |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF24 | zinc finger protein 24 |
| ZNF350 | zinc finger protein 350 |
| ZNF750 | zinc finger protein 750 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BBS10 | Bardet-Biedl syndrome 10 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAPN15 | calpain 15 |
| CASD1 | CAS1 domain containing 1 |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC186 | coiled-coil domain containing 186 |
| CDK20 | cyclin-dependent kinase 20 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DOCK1 | dedicator of cytokinesis 1 |
| EFNA3 | ephrin-A3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAM53B | family with sequence similarity 53, member B |
| FBXW12 | F-box and WD repeat domain containing 12 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| HOXC13 | homeobox C13 |
| IFI6 | interferon, alpha-inducible protein 6 |
| KLF11 | Kruppel-like factor 11 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGC12488 | |
| MTMR6 | myotubularin related protein 6 |
| MVD | mevalonate (diphospho) decarboxylase |
| MVP | major vault protein |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NBEAL2 | neurobeachin-like 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| NPY5R | neuropeptide Y receptor Y5 |
| NRBF2 | nuclear receptor binding factor 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PPAN | peter pan homolog (Drosophila) |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRPH | peripherin |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| QDPR | quinoid dihydropteridine reductase |
| RAB33B | RAB33B, member RAS oncogene family |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RWDD2A | RWD domain containing 2A |
| SAV1 | salvador family WW domain containing protein 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIRT2 | sirtuin 2 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TCTN1 | tectonic family member 1 |
| TESK1 | testis-specific kinase 1 |
| THBS3 | thrombospondin 3 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM254 | transmembrane protein 254 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TTBK2 | tau tubulin kinase 2 |
| TUBA3C | tubulin, alpha 3c |
| UBQLN4 | ubiquilin 4 |
| VGF | VGF nerve growth factor inducible |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| WDR4 | WD repeat domain 4 |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZNF14 | zinc finger protein 14 |
| ZNF227 | zinc finger protein 227 |
| ZNF692 | zinc finger protein 692 |
| ZNF721 | zinc finger protein 721 |
| ZNF767P | zinc finger family member 767, pseudogene |
