(-)-atenolol-6444 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the (-)-atenolol-6444 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADCK2 aarF domain containing kinase 2
AFF1 AF4/FMR2 family, member 1
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
ANXA2P3 annexin A2 pseudogene 3
APOA1 apolipoprotein A-I
AQP1 aquaporin 1 (Colton blood group)
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ART1 ADP-ribosyltransferase 1
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BTG2 BTG family, member 2
C5AR1 complement component 5a receptor 1
CABP1 calcium binding protein 1
CALD1 caldesmon 1
CD82 CD82 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIZ1 CDKN1A interacting zinc finger protein 1
CNOT4 CCR4-NOT transcription complex, subunit 4
CST4 cystatin S
CXCR6 chemokine (C-X-C motif) receptor 6
CYHR1 cysteine/histidine-rich 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DSC1 desmocollin 1
EDDM3B epididymal protein 3B
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FABP1 fatty acid binding protein 1, liver
FAM171A1 family with sequence similarity 171, member A1
FHL1 four and a half LIM domains 1
FLJ11292
GPATCH4 G patch domain containing 4
HCRP1 hepatocellular carcinoma-related HCRP1
HIF3A hypoxia inducible factor 3, alpha subunit
HPSE2 heparanase 2 (inactive)
IGFBP5 insulin-like growth factor binding protein 5
IL18BP interleukin 18 binding protein
IRF4 interferon regulatory factor 4
KANSL3 KAT8 regulatory NSL complex subunit 3
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCTD17 potassium channel tetramerization domain containing 17
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK11 kallikrein-related peptidase 11
KRIT1 KRIT1, ankyrin repeat containing
KRT6B keratin 6B, type II
LAMA4 laminin, alpha 4
LOXL2 lysyl oxidase-like 2
MFAP5 microfibrillar associated protein 5
MKL1 megakaryoblastic leukemia (translocation) 1
MSC musculin
MX1 MX dynamin-like GTPase 1
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYOZ1 myozenin 1
NKX3-2 NK3 homeobox 2
PAPPA2 pappalysin 2
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDIA2 protein disulfide isomerase family A, member 2
PIGR polymeric immunoglobulin receptor
PLAC4 placenta-specific 4
PLAG1 pleiomorphic adenoma gene 1
PLK3 polo-like kinase 3
POMT2 protein-O-mannosyltransferase 2
PTGFR prostaglandin F receptor (FP)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
QSER1 glutamine and serine rich 1
RAB35 RAB35, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RYR1 ryanodine receptor 1 (skeletal)
SCG2 secretogranin II
SCNN1B sodium channel, non voltage gated 1 beta subunit
SIRT4 sirtuin 4
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMG7-AS1 SMG7 antisense RNA 1
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPDEF SAM pointed domain containing ETS transcription factor
TAPBP TAP binding protein (tapasin)
TCP10L t-complex 10-like
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TRD T cell receptor delta locus
TRIM22 tripartite motif containing 22
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TSHR thyroid stimulating hormone receptor
TUBA3C tubulin, alpha 3c
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WIPF1 WAS/WASL interacting protein family, member 1
WNT5B wingless-type MMTV integration site family, member 5B
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF208 zinc finger protein 208

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AHCTF1 AT hook containing transcription factor 1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ANXA1 annexin A1
APOD apolipoprotein D
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAG4 BCL2-associated athanogene 4
BAGE B melanoma antigen
C10ORF95 chromosome 10 open reading frame 95
C11ORF95 chromosome 11 open reading frame 95
CBX4 chromobox homolog 4
CENPJ centromere protein J
CENPQ centromere protein Q
CEP97 centrosomal protein 97kDa
CFD complement factor D (adipsin)
CHML choroideremia-like (Rab escort protein 2)
COQ6 coenzyme Q6 monooxygenase
CRYZL1 crystallin, zeta (quinone reductase)-like 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DNAH17 dynein, axonemal, heavy chain 17
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EGR3 early growth response 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FBXL15 F-box and leucine-rich repeat protein 15
FBXO2 F-box protein 2
GALK1 galactokinase 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GID4 GID complex subunit 4
GPC3 glypican 3
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H1B histone cluster 1, H1b
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H4D histone cluster 1, H4d
HOXC5 homeobox C5
HSPB6 heat shock protein, alpha-crystallin-related, B6
IL4R interleukin 4 receptor
IRAK4 interleukin-1 receptor-associated kinase 4
ITPKB inositol-trisphosphate 3-kinase B
JMJD4 jumonji domain containing 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0754 KIAA0754
LAMA3 laminin, alpha 3
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC100131532 uncharacterized LOC100131532
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LYPD1 LY6/PLAUR domain containing 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAN2C1 mannosidase, alpha, class 2C, member 1
MCTP1 multiple C2 domains, transmembrane 1
NEK11 NIMA-related kinase 11
NFE2L3 nuclear factor, erythroid 2-like 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PER3 period circadian clock 3
PGBD5 piggyBac transposable element derived 5
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLH polymerase (DNA directed), eta
PRICKLE3 prickle homolog 3 (Drosophila)
PROL1 proline rich, lacrimal 1
PRSS16 protease, serine, 16 (thymus)
PTPRU protein tyrosine phosphatase, receptor type, U
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL39L ribosomal protein L39-like
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLMO1 slowmo homolog 1 (Drosophila)
SNIP1 Smad nuclear interacting protein 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SRD5A3 steroid 5 alpha-reductase 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYBU syntabulin (syntaxin-interacting)
SYCP2 synaptonemal complex protein 2
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TCHH trichohyalin
TCTN1 tectonic family member 1
THUMPD2 THUMP domain containing 2
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC5 transmembrane channel-like 5
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TWF2 twinfilin actin binding protein 2
UBXN6 UBX domain protein 6
USP20 ubiquitin specific peptidase 20
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR4 WD repeat domain 4
WLS wntless Wnt ligand secretion mediator
ZNF276 zinc finger protein 276
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF37BP zinc finger protein 37B, pseudogene
ZNF442 zinc finger protein 442
ZNF675 zinc finger protein 675