(-)-atenolol-6725 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

195 genes differentially expressed following the (-)-atenolol-6725 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADAP1 ArfGAP with dual PH domains 1
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPTL2 angiopoietin-like 2
APAF1 apoptotic peptidase activating factor 1
BLZF1 basic leucine zipper nuclear factor 1
BMP8B bone morphogenetic protein 8b
C14ORF79 chromosome 14 open reading frame 79
C21ORF2 chromosome 21 open reading frame 2
C8A complement component 8, alpha polypeptide
C9ORF156 chromosome 9 open reading frame 156
CBLN1 cerebellin 1 precursor
CCDC170 coiled-coil domain containing 170
CCDC40 coiled-coil domain containing 40
CD58 CD58 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK13 cyclin-dependent kinase 13
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CES3 carboxylesterase 3
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CNGA1 cyclic nucleotide gated channel alpha 1
CNTFR ciliary neurotrophic factor receptor
COBLL1 cordon-bleu WH2 repeat protein-like 1
CRH corticotropin releasing hormone
CRY2 cryptochrome circadian clock 2
CTRC chymotrypsin C (caldecrin)
DENND1C DENN/MADD domain containing 1C
DHRS7 dehydrogenase/reductase (SDR family) member 7
E2F4 E2F transcription factor 4, p107/p130-binding
EDA ectodysplasin A
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FBXO40 F-box protein 40
FGB fibrinogen beta chain
FKBP8 FK506 binding protein 8, 38kDa
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOXL1 forkhead box L1
FRMD4B FERM domain containing 4B
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GON4L gon-4-like (C. elegans)
GPR75 G protein-coupled receptor 75
HIST1H4F histone cluster 1, H4f
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGLJ3 immunoglobulin lambda joining 3
IL11 interleukin 11
IL12A interleukin 12A
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IQSEC2 IQ motif and Sec7 domain 2
KIAA0485 uncharacterized LOC57235
KRT2 keratin 2, type II
LAMB4 laminin, beta 4
LAMC2 laminin, gamma 2
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MANBA mannosidase, beta A, lysosomal
MAU2 MAU2 sister chromatid cohesion factor
MYO9B myosin IXB
NOD1 nucleotide-binding oligomerization domain containing 1
NPAS3 neuronal PAS domain protein 3
NPC1 Niemann-Pick disease, type C1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUDC nudC nuclear distribution protein
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A
PPP5C protein phosphatase 5, catalytic subunit
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAB3D RAB3D, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RB1 retinoblastoma 1
RPS3A ribosomal protein S3A
RUNX1 runt-related transcription factor 1
RXRB retinoid X receptor, beta
SBNO1 strawberry notch homolog 1 (Drosophila)
SEPP1 selenoprotein P, plasma, 1
SGSM3 small G protein signaling modulator 3
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOGA1 suppressor of glucose, autophagy associated 1
SPATA6 spermatogenesis associated 6
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SUSD5 sushi domain containing 5
TAGLN3 transgelin 3
TCF12 transcription factor 12
TFEB transcription factor EB
TLX2 T-cell leukemia homeobox 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
VDAC3 voltage-dependent anion channel 3
WSB1 WD repeat and SOCS box containing 1
ZBTB20 zinc finger and BTB domain containing 20
ZFAND5 zinc finger, AN1-type domain 5
ZFHX2 zinc finger homeobox 2
ZNF334 zinc finger protein 334
ZNF609 zinc finger protein 609
ZNF688 zinc finger protein 688
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACE angiotensin I converting enzyme
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAM23 ADAM metallopeptidase domain 23
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANOS1 anosmin 1
ANXA10 annexin A10
ANXA2P1 annexin A2 pseudogene 1
APOC4 apolipoprotein C-IV
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARMCX4 armadillo repeat containing, X-linked 4
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AURKC aurora kinase C
BATF3 basic leucine zipper transcription factor, ATF-like 3
BEX1 brain expressed, X-linked 1
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF63 chromosome 11 open reading frame 63
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CAMKMT calmodulin-lysine N-methyltransferase
CAPN15 calpain 15
CARTPT CART prepropeptide
CASZ1 castor zinc finger 1
CCNA1 cyclin A1
CD3D CD3d molecule, delta (CD3-TCR complex)
CDON cell adhesion associated, oncogene regulated
CENPO centromere protein O
CIDEC cell death-inducing DFFA-like effector c
CLDN15 claudin 15
CLIC3 chloride intracellular channel 3
CNTNAP3B contactin associated protein-like 3B
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CYB5R2 cytochrome b5 reductase 2
DAGLA diacylglycerol lipase, alpha
DSPP dentin sialophosphoprotein
EPHA7 EPH receptor A7
ERO1LB ERO1-like beta (S. cerevisiae)
EYA3 EYA transcriptional coactivator and phosphatase 3
F3 coagulation factor III (thromboplastin, tissue factor)
FAM186A family with sequence similarity 186, member A
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMPD1 FERM and PDZ domain containing 1
GAS8 growth arrest-specific 8
GIF gastric intrinsic factor (vitamin B synthesis)
GLS2 glutaminase 2 (liver, mitochondrial)
GPC3 glypican 3
GRAMD4 GRAM domain containing 4
GRM4 glutamate receptor, metabotropic 4
H2AFJ H2A histone family, member J
HESX1 HESX homeobox 1
HOXC4 homeobox C4
HSPB6 heat shock protein, alpha-crystallin-related, B6
ICOS inducible T-cell co-stimulator
INCENP inner centromere protein antigens 135/155kDa
ITGB7 integrin, beta 7
KLF13 Kruppel-like factor 13
KRT34 keratin 34, type I
LPAR4 lysophosphatidic acid receptor 4
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MAP6D1 MAP6 domain containing 1
MCM9 minichromosome maintenance complex component 9
MGP matrix Gla protein
MLYCD malonyl-CoA decarboxylase
MOCS1 molybdenum cofactor synthesis 1
MTSS1L metastasis suppressor 1-like
NABP1 nucleic acid binding protein 1
NEUROD1 neuronal differentiation 1
NOL12 nucleolar protein 12
NPM3 nucleophosmin/nucleoplasmin 3
PAIP2B poly(A) binding protein interacting protein 2B
PAQR6 progestin and adipoQ receptor family member VI
PDE8B phosphodiesterase 8B
PKD2L2 polycystic kidney disease 2-like 2
PRAMEF10 PRAME family member 10
RAB33B RAB33B, member RAS oncogene family
RAB40A RAB40A, member RAS oncogene family
RBL1 retinoblastoma-like 1
RIBC2 RIB43A domain with coiled-coils 2
SLC16A6 solute carrier family 16, member 6
SLC35F6 solute carrier family 35, member F6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPIDR scaffolding protein involved in DNA repair
STON1 stonin 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TESPA1 thymocyte expressed, positive selection associated 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSNAXIP1 translin-associated factor X interacting protein 1
TUBA4B tubulin, alpha 4b
UBXN8 UBX domain protein 8
WDR78 WD repeat domain 78
WNT10B wingless-type MMTV integration site family, member 10B
ZNF141 zinc finger protein 141
ZNF442 zinc finger protein 442
ZNF675 zinc finger protein 675
ZNF816 zinc finger protein 816