(-)-isoprenaline-4495 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the (-)-isoprenaline-4495 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACRV1 acrosomal vesicle protein 1
ACSL5 acyl-CoA synthetase long-chain family member 5
AKAP12 A kinase (PRKA) anchor protein 12
AKR1C2 aldo-keto reductase family 1, member C2
ALPK1 alpha-kinase 1
ANXA10 annexin A10
APOE apolipoprotein E
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARTN artemin
BAAT bile acid CoA:amino acid N-acyltransferase
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2A1 BCL2-related protein A1
BMP2 bone morphogenetic protein 2
C22ORF46 chromosome 22 open reading frame 46
C5 complement component 5
CD24 CD24 molecule
CD248 CD248 molecule, endosialin
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD68 CD68 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMIP cell migration inducing protein, hyaluronan binding
CFAP45 cilia and flagella associated protein 45
COL3A1 collagen, type III, alpha 1
CREM cAMP responsive element modulator
CTH cystathionine gamma-lyase
DGCR2 DiGeorge syndrome critical region gene 2
DMBT1 deleted in malignant brain tumors 1
DNASE1L3 deoxyribonuclease I-like 3
DUSP1 dual specificity phosphatase 1
EPAS1 endothelial PAS domain protein 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV1 ets variant 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GK glycerol kinase
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPRC5A G protein-coupled receptor, class C, group 5, member A
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IL11 interleukin 11
IL1R2 interleukin 1 receptor, type II
IL33R interleukin 33 receptor
INSL4 insulin-like 4 (placenta)
ISG20 interferon stimulated exonuclease gene 20kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
LAMA4 laminin, alpha 4
LYPD3 LY6/PLAUR domain containing 3
MAP7 microtubule-associated protein 7
MCL1 myeloid cell leukemia 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYL10 myosin, light chain 10, regulatory
NPY neuropeptide Y
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTF3 neurotrophin 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PADI2 peptidyl arginine deiminase, type II
PDE10A phosphodiesterase 10A
PDE4B phosphodiesterase 4B, cAMP-specific
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
POU2F2 POU class 2 homeobox 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGES prostaglandin E synthase
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTPRU protein tyrosine phosphatase, receptor type, U
RERE arginine-glutamic acid dipeptide (RE) repeats
S100P S100 calcium binding protein P
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SMOX spermine oxidase
STC1 stanniocalcin 1
STOML1 stomatin (EPB72)-like 1
SUGP1 SURP and G patch domain containing 1
TCP10 t-complex 10
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TGFB2 transforming growth factor, beta 2
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNS1 tensin 1
TP53I11 tumor protein p53 inducible protein 11
TRIM29 tripartite motif containing 29
TTLL4 tubulin tyrosine ligase-like family member 4
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
UTS2 urotensin 2
WSB1 WD repeat and SOCS box containing 1
ZBTB38 zinc finger and BTB domain containing 38
ZFP64 ZFP64 zinc finger protein
ZNF343 zinc finger protein 343
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ADGRB2 adhesion G protein-coupled receptor B2
ADRB2 adrenoceptor beta 2, surface
APOL6 apolipoprotein L, 6
ARHGAP24 Rho GTPase activating protein 24
ARMCX4 armadillo repeat containing, X-linked 4
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATXN2 ataxin 2
AURKC aurora kinase C
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
CAMKMT calmodulin-lysine N-methyltransferase
CBX4 chromobox homolog 4
CCDC85C coiled-coil domain containing 85C
CCL27 chemokine (C-C motif) ligand 27
CD101 CD101 molecule
CD82 CD82 molecule
CDHR2 cadherin-related family member 2
COBL cordon-bleu WH2 repeat protein
CRY2 cryptochrome circadian clock 2
CTGF connective tissue growth factor
CUEDC1 CUE domain containing 1
CYR61 cysteine-rich, angiogenic inducer, 61
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EDC4 enhancer of mRNA decapping 4
EGF epidermal growth factor
EHD3 EH-domain containing 3
ERAP2 endoplasmic reticulum aminopeptidase 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM102A family with sequence similarity 102, member A
FAM50B family with sequence similarity 50, member B
FAT4 FAT atypical cadherin 4
FBXL7 F-box and leucine-rich repeat protein 7
FBXO2 F-box protein 2
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FJX1 four jointed box 1 (Drosophila)
G0S2 G0/G1 switch 2
GBX2 gastrulation brain homeobox 2
GLS2 glutaminase 2 (liver, mitochondrial)
GMPR guanosine monophosphate reductase
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIST1H3G histone cluster 1, H3g
HLX H2.0-like homeobox
HPN hepsin
IFI6 interferon, alpha-inducible protein 6
IL11RA interleukin 11 receptor, alpha
INHBB inhibin, beta B
IQSEC2 IQ motif and Sec7 domain 2
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KRT31 keratin 31, type I
LIMD2 LIM domain containing 2
LMTK1 lemur tail kinase 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LTC4S leukotriene C4 synthase
LYRM9 LYR motif containing 9
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MT1M metallothionein 1M
MXRA8 matrix-remodelling associated 8
NBEAL2 neurobeachin-like 2
NPDC1 neural proliferation, differentiation and control, 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDHA9 protocadherin alpha 9
PCSK7 proprotein convertase subtilisin/kexin type 7
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLK2 polo-like kinase 2
PODXL2 podocalyxin-like 2
PRR16 proline rich 16
PTX3 pentraxin 3, long
RAD54L2 RAD54-like 2 (S. cerevisiae)
RNF2 ring finger protein 2
ROGDI rogdi homolog (Drosophila)
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUNX1-IT1 RUNX1 intronic transcript 1
SCN9A sodium channel, voltage gated, type IX alpha subunit
SLC22A14 solute carrier family 22, member 14
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SNPH syntaphilin
SPTBN2 spectrin, beta, non-erythrocytic 2
SUGCT succinyl-CoA:glutarate-CoA transferase
TEX15 testis expressed 15
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TKFC triokinase/FMN cyclase
TPRA1 transmembrane protein, adipocyte asscociated 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TSC22D4 TSC22 domain family, member 4
TSPAN2 tetraspanin 2
VEZT vezatin, adherens junctions transmembrane protein
WDR25 WD repeat domain 25
WDR4 WD repeat domain 4
WNT7A wingless-type MMTV integration site family, member 7A
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF442 zinc finger protein 442
ZNF74 zinc finger protein 74