(-)-isoprenaline-6833 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the (-)-isoprenaline-6833 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACAN aggrecan
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDOB aldolase B, fructose-bisphosphate
AMACR alpha-methylacyl-CoA racemase
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ASIC1 acid sensing (proton gated) ion channel 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BIN1 bridging integrator 1
C21ORF2 chromosome 21 open reading frame 2
CALD1 caldesmon 1
CD6 CD6 molecule
CDON cell adhesion associated, oncogene regulated
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CPQ carboxypeptidase Q
CTIF CBP80/20-dependent translation initiation factor
CXCR4 chemokine (C-X-C motif) receptor 4
DOC2B double C2-like domains, beta
DUSP4 dual specificity phosphatase 4
EHD2 EH-domain containing 2
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ESR1 estrogen receptor 1
ETV6 ets variant 6
FAM65A family with sequence similarity 65, member A
FAM65B family with sequence similarity 65, member B
FGF13 fibroblast growth factor 13
FSCN1 fascin actin-bundling protein 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GNAS GNAS complex locus
GPR176 G protein-coupled receptor 176
HIST1H1T histone cluster 1, H1t
HIST1H4C histone cluster 1, H4c
HLA-DMB major histocompatibility complex, class II, DM beta
IL32 interleukin 32
IL36R interleukin 36 receptor
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQCC IQ motif containing C
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KLF13 Kruppel-like factor 13
KLK8 kallikrein-related peptidase 8
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT31 keratin 31, type I
LAMC2 laminin, gamma 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMK1 LIM domain kinase 1
LIN7A lin-7 homolog A (C. elegans)
LOX lysyl oxidase
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MARK4 MAP/microtubule affinity-regulating kinase 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MID1 midline 1
MMP25 matrix metallopeptidase 25
MYH14 myosin, heavy chain 14, non-muscle
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
MYO7B myosin VIIB
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOD2 nucleotide-binding oligomerization domain containing 2
NRIP3 nuclear receptor interacting protein 3
PER1 period circadian clock 1
PER2 period circadian clock 2
PHACTR1 phosphatase and actin regulator 1
PHOX2A paired-like homeobox 2a
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLSCR1 phospholipid scramblase 1
POFUT1 protein O-fucosyltransferase 1
POPDC3 popeye domain containing 3
POU6F1 POU class 6 homeobox 1
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
R3HDM1 R3H domain containing 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERGEF secretion regulating guanine nucleotide exchange factor
SIK3 SIK family kinase 3
SLC12A8 solute carrier family 12, member 8
SLC17A2 solute carrier family 17, member 2
SLC35E2 solute carrier family 35, member E2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPAG8 sperm associated antigen 8
SPEG SPEG complex locus
SPX spexin hormone
SYNJ1 synaptojanin 1
TAT tyrosine aminotransferase
TBX5 T-box 5
TDRD12 tudor domain containing 12
TTC38 tetratricopeptide repeat domain 38
USP27X ubiquitin specific peptidase 27, X-linked
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
ZBTB17 zinc finger and BTB domain containing 17
ZBTB7A zinc finger and BTB domain containing 7A
ZC3H7B zinc finger CCCH-type containing 7B
ZNF528 zinc finger protein 528
ZNF639 zinc finger protein 639
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AKR1C2 aldo-keto reductase family 1, member C2
ANP32A-IT1 ANP32A intronic transcript 1
ARPIN actin-related protein 2/3 complex inhibitor
B9D2 B9 protein domain 2
BTF3P11 basic transcription factor 3 pseudogene 11
C4ORF29 chromosome 4 open reading frame 29
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD302 CD302 molecule
CHMP7 charged multivesicular body protein 7
CLCF1 cardiotrophin-like cytokine factor 1
CRY2 cryptochrome circadian clock 2
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DEAF1 DEAF1 transcription factor
DNAL4 dynein, axonemal, light chain 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FAM204A family with sequence similarity 204, member A
FAM46C family with sequence similarity 46, member C
FHOD1 formin homology 2 domain containing 1
GAA glucosidase, alpha; acid
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L2 galactosidase, beta 1-like 2
GLS2 glutaminase 2 (liver, mitochondrial)
GRTP1 growth hormone regulated TBC protein 1
GSTA4 glutathione S-transferase alpha 4
GSTTP1 glutathione S-transferase theta pseudogene 1
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HOXC8 homeobox C8
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
INO80D INO80 complex subunit D
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KLHL25 kelch-like family member 25
KREMEN2 kringle containing transmembrane protein 2
KRT16 keratin 16, type I
LHX6 LIM homeobox 6
MAN2C1 mannosidase, alpha, class 2C, member 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
METTL2B methyltransferase like 2B
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NABP2 nucleic acid binding protein 2
NAV2 neuron navigator 2
OVGP1 oviductal glycoprotein 1, 120kDa
PADI1 peptidyl arginine deiminase, type I
PADI3 peptidyl arginine deiminase, type III
PARD6A par-6 family cell polarity regulator alpha
PARG poly (ADP-ribose) glycohydrolase
PCSK7 proprotein convertase subtilisin/kexin type 7
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PHACTR4 phosphatase and actin regulator 4
PHEX phosphate regulating endopeptidase homolog, X-linked
PILRB paired immunoglobin-like type 2 receptor beta
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PNPLA6 patatin-like phospholipase domain containing 6
POM121 POM121 transmembrane nucleoporin
PP14571 uncharacterized LOC100130449
PPT2 palmitoyl-protein thioesterase 2
PRF1 perforin 1 (pore forming protein)
RAB3A RAB3A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RFXAP regulatory factor X-associated protein
RPAP2 RNA polymerase II associated protein 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SAYSD1 SAYSVFN motif domain containing 1
SDC3 syndecan 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SND1-IT1 SND1 intronic transcript 1
SNHG20 small nucleolar RNA host gene 20
SOWAHC sosondowah ankyrin repeat domain family member C
STAG3 stromal antigen 3
STK11 serine/threonine kinase 11
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TEP1 telomerase-associated protein 1
TGFB3 transforming growth factor, beta 3
TMEM121 transmembrane protein 121
TOM1 target of myb1 (chicken)
TTBK2 tau tubulin kinase 2
USB1 U6 snRNA biogenesis 1
VEZT vezatin, adherens junctions transmembrane protein
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR62 WD repeat domain 62
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZNF324 zinc finger protein 324
ZNF652 zinc finger protein 652
ZNF668 zinc finger protein 668
ZNF747 zinc finger protein 747