| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.217423 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.205268 |
| PLAT | plasminogen activator, tissue | 0.180563 |
| MT2A | metallothionein 2A | 0.12226 |
| FLNB | filamin B, beta | 0.100424 |
| CD44 | CD44 molecule (Indian blood group) | 0.0967474 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0945001 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0918452 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0872376 |
| APP | amyloid beta (A4) precursor protein | 0.0728201 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.072595 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0680948 |
| DST | dystonin | 0.0678073 |
| SEPTIN9 | septin 9 | 0.0664932 |
| BCL2L1 | BCL2-like 1 | 0.0597569 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0588016 |
| HDAC9 | histone deacetylase 9 | 0.0573061 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0562297 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.052504 |
| MB21D2 | Mab-21 domain containing 2 | 0.0519653 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0517471 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0504514 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0495428 |
| PRELID2 | PRELI domain containing 2 | 0.0489588 |
| GLIS3 | GLIS family zinc finger 3 | 0.0488992 |
| LDHA | lactate dehydrogenase A | 0.0478912 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0468237 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.046404 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0457808 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0449981 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0446775 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0440213 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0436749 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0397816 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0394779 |
| FLNA | filamin A, alpha | 0.0386537 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0385165 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0380883 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0376617 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0372274 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0370173 |
| SFTPA2 | surfactant protein A2 | 0.0360133 |
| MKI67 | marker of proliferation Ki-67 | 0.0359217 |
| SVIL | supervillin | 0.0350572 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0348416 |
| CENPF | centromere protein F, 350/400kDa | 0.0347083 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0338586 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.033725 |
| SMYD3 | SET and MYND domain containing 3 | 0.0333814 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0326877 |
| SMAD3 | SMAD family member 3 | 0.0324502 |
| ANLN | anillin, actin binding protein | 0.0321342 |
| CLTC | clathrin, heavy chain (Hc) | 0.0317143 |
| BPTF | bromodomain PHD finger transcription factor | 0.0317046 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0316049 |
| PCM1 | pericentriolar material 1 | 0.03123 |
| ACTN1 | actinin, alpha 1 | 0.0310996 |
| ASPH | aspartate beta-hydroxylase | 0.0309555 |
| RUNX1 | runt-related transcription factor 1 | 0.0307963 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0303339 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.030287 |
| MYOF | myoferlin | 0.030276 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0301259 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0299583 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0298983 |
| ERBIN | erbb2 interacting protein | 0.0297293 |
| LAMB1 | laminin, beta 1 | 0.0296267 |
| FUS | FUS RNA binding protein | 0.0289852 |
| SET | SET nuclear proto-oncogene | 0.0289848 |
| EZR | ezrin | 0.0287433 |
| DNMBP | dynamin binding protein | 0.0286782 |
| ATXN1 | ataxin 1 | 0.028446 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0281716 |
| EGR1 | early growth response 1 | 0.028138 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0281262 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0280363 |
| DSPP | dentin sialophosphoprotein | 0.02785 |
| MYADM | myeloid-associated differentiation marker | 0.0277262 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.027715 |
| JMJD1C | jumonji domain containing 1C | 0.0275122 |
| TXNRD1 | thioredoxin reductase 1 | 0.0265494 |
| S100A10 | S100 calcium binding protein A10 | 0.0264901 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0264895 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0260159 |
| IL6ST | interleukin 6 signal transducer | 0.0259697 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0258916 |
| B2M | beta-2-microglobulin | 0.0257377 |
| STC1 | stanniocalcin 1 | 0.0252843 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0249115 |
| ARRDC3 | arrestin domain containing 3 | 0.024889 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0248874 |
| ENO1 | enolase 1, (alpha) | 0.0246244 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0243748 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0243472 |
| SON | SON DNA binding protein | 0.0242745 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0240574 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0239944 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0238493 |
| MINK1 | misshapen-like kinase 1 | 0.0238286 |
| RRM2 | ribonucleotide reductase M2 | 0.0238085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.203314 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.164236 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.15779 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.154514 |
| VIM | vimentin | -0.120265 |
| TMSB10 | thymosin beta 10 | -0.100961 |
| S100A6 | S100 calcium binding protein A6 | -0.0911044 |
| SLC39A11 | solute carrier family 39, member 11 | -0.081153 |
| CDH13 | cadherin 13 | -0.0803573 |
| CCND1 | cyclin D1 | -0.0788343 |
| COL5A1 | collagen, type V, alpha 1 | -0.0782071 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0761539 |
| AHNAK | AHNAK nucleoprotein | -0.0742534 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0697872 |
| LOX | lysyl oxidase | -0.0665997 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0660991 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0653871 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0645189 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0638081 |
| COL5A2 | collagen, type V, alpha 2 | -0.0626943 |
| MSI2 | musashi RNA-binding protein 2 | -0.0615421 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0611183 |
| CAVIN1 | caveolae associated protein 1 | -0.0571272 |
| LMNA | lamin A/C | -0.0567204 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0524464 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0497845 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0495048 |
| POTEF | POTE ankyrin domain family, member F | -0.0476255 |
| CSTB | cystatin B (stefin B) | -0.0467464 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0466998 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0450978 |
| TAGLN2 | transgelin 2 | -0.0448312 |
| FN1 | fibronectin 1 | -0.0439851 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0439045 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0433119 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.042198 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0418825 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0417477 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0414053 |
| COL1A2 | collagen, type I, alpha 2 | -0.0413528 |
| AUTS2 | autism susceptibility candidate 2 | -0.0402349 |
| MEIS2 | Meis homeobox 2 | -0.0399097 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0393272 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0392993 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0391247 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0381609 |
| TPM4 | tropomyosin 4 | -0.0372635 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0366857 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0359011 |
| ACTG1 | actin gamma 1 | -0.035506 |
| FSTL1 | follistatin-like 1 | -0.0354302 |
| FBN1 | fibrillin 1 | -0.0352316 |
| CUX1 | cut-like homeobox 1 | -0.035201 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0345532 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0343938 |
| TNS3 | tensin 3 | -0.0341005 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0334 |
| S100A4 | S100 calcium binding protein A4 | -0.0326835 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0325796 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.0323979 |
| SUCNR1 | succinate receptor 1 | -0.0323911 |
| INSIG1 | insulin induced gene 1 | -0.0322156 |
| IL7R | interleukin 7 receptor | -0.032095 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0319186 |
| MAP1B | microtubule-associated protein 1B | -0.0318445 |
| RPL35A | ribosomal protein L35a | -0.0309253 |
| PTMA | prothymosin, alpha | -0.0290468 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0283126 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0282199 |
| FRMD4A | FERM domain containing 4A | -0.0280225 |
| RIGI | RNA sensor RIG-I | -0.0273587 |
| GNAS | GNAS complex locus | -0.0273452 |
| KRT81 | keratin 81, type II | -0.0263634 |
| FTL | ferritin, light polypeptide | -0.0258633 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0255407 |
| LOXL2 | lysyl oxidase-like 2 | -0.0253858 |
| THBS2 | thrombospondin 2 | -0.0253381 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0253341 |
| PFN1 | profilin 1 | -0.0247359 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.024454 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0242063 |
| COL1A1 | collagen, type I, alpha 1 | -0.0230966 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0229614 |
| FOSL1 | FOS-like antigen 1 | -0.0227697 |
| MT1X | metallothionein 1X | -0.0223746 |
| SRPK2 | SRSF protein kinase 2 | -0.0216903 |
| TMEM263 | transmembrane protein 263 | -0.0216277 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0215567 |
| IL32 | interleukin 32 | -0.0214831 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0214192 |
| TOX | thymocyte selection-associated high mobility group box | -0.0211577 |
| GOLGA4 | golgin A4 | -0.0211416 |
| TAPBP | TAP binding protein (tapasin) | -0.0211259 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0210296 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0209805 |
| RRBP1 | ribosome binding protein 1 | -0.0209218 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0207941 |
| MX2 | MX dynamin-like GTPase 2 | -0.0207288 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.020672 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0206456 |
