| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.223472 |
| AREG | amphiregulin | 0.130482 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.101702 |
| RPS12 | ribosomal protein S12 | 0.101378 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0827465 |
| RRM2 | ribonucleotide reductase M2 | 0.0778237 |
| RPS8 | ribosomal protein S8 | 0.0763589 |
| RPS3 | ribosomal protein S3 | 0.0735876 |
| ANXA1 | annexin A1 | 0.0732417 |
| HMGA2 | high mobility group AT-hook 2 | 0.0690185 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0689615 |
| TMSB10 | thymosin beta 10 | 0.0647062 |
| ASPH | aspartate beta-hydroxylase | 0.0514007 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0505759 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0505309 |
| JMJD1C | jumonji domain containing 1C | 0.0491965 |
| YAP1 | Yes-associated protein 1 | 0.0490802 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0487924 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0486319 |
| RPL37A | ribosomal protein L37a | 0.0485055 |
| FTL | ferritin, light polypeptide | 0.0484303 |
| RPL23 | ribosomal protein L23 | 0.0482066 |
| PCDH7 | protocadherin 7 | 0.0479891 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0473082 |
| MORF4L2 | mortality factor 4 like 2 | 0.0471782 |
| MKI67 | marker of proliferation Ki-67 | 0.0466741 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0465021 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.045789 |
| WWOX | WW domain containing oxidoreductase | 0.0454536 |
| CALR | calreticulin | 0.045304 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0449912 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0417433 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0415795 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0412073 |
| RPS4X | ribosomal protein S4, X-linked | 0.0393228 |
| RACK1 | receptor for activated C kinase 1 | 0.0381623 |
| FUS | FUS RNA binding protein | 0.0375327 |
| RPL36 | ribosomal protein L36 | 0.0374111 |
| TPI1 | triosephosphate isomerase 1 | 0.0373537 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0363085 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0362836 |
| DST | dystonin | 0.0362073 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0356443 |
| NLGN1 | neuroligin 1 | 0.03545 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0352068 |
| RPS29 | ribosomal protein S29 | 0.0349624 |
| RPS2 | ribosomal protein S2 | 0.0343046 |
| RPS19 | ribosomal protein S19 | 0.0339492 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0334314 |
| MTAP | methylthioadenosine phosphorylase | 0.0333476 |
| RPL31 | ribosomal protein L31 | 0.0331767 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0328132 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0327862 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0315684 |
| RPS17 | ribosomal protein S17 | 0.0307896 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0305914 |
| CCDC88A | coiled-coil domain containing 88A | 0.030205 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.030122 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0297344 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0293873 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.029386 |
| RPL26 | ribosomal protein L26 | 0.0289532 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0288888 |
| INTS6 | integrator complex subunit 6 | 0.0283631 |
| EZR | ezrin | 0.027911 |
| YBX3 | Y box binding protein 3 | 0.0277087 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0275901 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0275644 |
| EDARADD | EDAR-associated death domain | 0.0272402 |
| PRDX1 | peroxiredoxin 1 | 0.0270894 |
| VMP1 | vacuole membrane protein 1 | 0.0270416 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.026931 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0265002 |
| PRELID2 | PRELI domain containing 2 | 0.0264741 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0264296 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0264105 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0257563 |
| ENO1 | enolase 1, (alpha) | 0.0253688 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.025165 |
| RPS27 | ribosomal protein S27 | 0.0248448 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0247917 |
| CANX | calnexin | 0.0245948 |
| SET | SET nuclear proto-oncogene | 0.0245106 |
| NEBL | nebulette | 0.0240829 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | 0.0240585 |
| RPL12 | ribosomal protein L12 | 0.0239899 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0238526 |
| RPL36A | ribosomal protein L36a | 0.0237802 |
| RPS23 | ribosomal protein S23 | 0.0237087 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | 0.0233491 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0226705 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0222355 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0222022 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0221499 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0221307 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0220472 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0219365 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.021898 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0217707 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0215802 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0748879 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0658078 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.062187 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0598517 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0472441 |
| MGAT4C | MGAT4 family, member C | -0.0445131 |
| CCN2 | cellular communication network factor 2 | -0.0444306 |
| PFN1 | profilin 1 | -0.0414605 |
| LOC112694756 | uncharaterized LOC112694756 | -0.040603 |
| PTMS | parathymosin | -0.0396615 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0382944 |
| CLDN1 | claudin 1 | -0.0363627 |
| POTEF | POTE ankyrin domain family, member F | -0.0360995 |
| CCNL1 | cyclin L1 | -0.0360397 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0360166 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0344337 |
| HMGA1 | high mobility group AT-hook 1 | -0.0335083 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0328264 |
| MMP12 | matrix metallopeptidase 12 | -0.032437 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0310772 |
| WDR43 | WD repeat domain 43 | -0.0305338 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0289228 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0288751 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0281706 |
| ZNF207 | zinc finger protein 207 | -0.027226 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0268618 |
| KLHL24 | kelch-like family member 24 | -0.0253741 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0244356 |
| HLA-A | major histocompatibility complex, class I, A | -0.0237536 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0236685 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0236405 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0235896 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0234267 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0234259 |
| WASF2 | WAS protein family, member 2 | -0.0233859 |
| MEMO1 | mediator of cell motility 1 | -0.0224048 |
| LDHB | lactate dehydrogenase B | -0.0221507 |
| ETNK1 | ethanolamine kinase 1 | -0.0221375 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0220019 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0216965 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0214211 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0213444 |
| RAB7A | RAB7A, member RAS oncogene family | -0.021014 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0209768 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0207277 |
| ECT2 | epithelial cell transforming 2 | -0.0205285 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.020464 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0202352 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0199163 |
| TMEM131 | transmembrane protein 131 | -0.0198088 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0192635 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0192398 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0192082 |
| GSK3B | glycogen synthase kinase 3 beta | -0.018863 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0183493 |
| NEK7 | NIMA-related kinase 7 | -0.0182241 |
| TMEM123 | transmembrane protein 123 | -0.0181891 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0181608 |
| TUBA1B | tubulin, alpha 1b | -0.0179062 |
| RPL35A | ribosomal protein L35a | -0.0178424 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0177039 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0174072 |
| MAP1B | microtubule-associated protein 1B | -0.0172819 |
| BCHE | butyrylcholinesterase | -0.0172177 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0170119 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0169383 |
| CCNG1 | cyclin G1 | -0.0169372 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0169106 |
| NKTR | natural killer cell triggering receptor | -0.01684 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0167051 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.0166664 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0164909 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.0163892 |
| CPOX | coproporphyrinogen oxidase | -0.0162042 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0159999 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0157988 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0153209 |
| RPLP0 | ribosomal protein, large, P0 | -0.0152809 |
| TGM2 | transglutaminase 2 | -0.0152688 |
| RHOA | ras homolog family member A | -0.0149965 |
| TXNRD1 | thioredoxin reductase 1 | -0.0149424 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0148966 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0148787 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0147975 |
| LMO7 | LIM domain 7 | -0.0146801 |
| CDK17 | cyclin-dependent kinase 17 | -0.0146494 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0145423 |
| ATN1 | atrophin 1 | -0.0144855 |
| SETD5 | SET domain containing 5 | -0.0144477 |
| CCNI | cyclin I | -0.0143668 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0143221 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | -0.014176 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0141686 |
| TCERG1 | transcription elongation regulator 1 | -0.0140213 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.013958 |
| RPS20 | ribosomal protein S20 | -0.0138155 |
| PCNX1 | pecanex 1 | -0.013794 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0137755 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0137424 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0136893 |
