| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRIP1 | nuclear receptor interacting protein 1 | 0.0699901 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0642964 |
| MT2A | metallothionein 2A | 0.0571321 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.05593 |
| MCL1 | myeloid cell leukemia 1 | 0.0557973 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0552156 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0501465 |
| FLNB | filamin B, beta | 0.0496894 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0469159 |
| RPS4X | ribosomal protein S4, X-linked | 0.0466617 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0450431 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0449031 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0440207 |
| RPL23 | ribosomal protein L23 | 0.0424711 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0420446 |
| RPS12 | ribosomal protein S12 | 0.0416033 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0407681 |
| RPS19 | ribosomal protein S19 | 0.0389307 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0380606 |
| RPS3 | ribosomal protein S3 | 0.0375857 |
| RPL37A | ribosomal protein L37a | 0.037538 |
| RPS17 | ribosomal protein S17 | 0.0359783 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0341073 |
| EGFR | epidermal growth factor receptor | 0.0332393 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0332363 |
| SMYD3 | SET and MYND domain containing 3 | 0.0313112 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0305792 |
| RPL26 | ribosomal protein L26 | 0.0289326 |
| BCL2L1 | BCL2-like 1 | 0.0287761 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0278434 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0275504 |
| ANGPTL4 | angiopoietin-like 4 | 0.0268012 |
| RPL18 | ribosomal protein L18 | 0.0254334 |
| PRRC2C | proline-rich coiled-coil 2C | 0.025053 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0247922 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0243703 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0236323 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0230773 |
| WWOX | WW domain containing oxidoreductase | 0.0229414 |
| FAT1 | FAT atypical cadherin 1 | 0.0225228 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0224849 |
| CMIP | c-Maf inducing protein | 0.022395 |
| RUNX1 | runt-related transcription factor 1 | 0.0208904 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0206057 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0200325 |
| RPL31 | ribosomal protein L31 | 0.0198505 |
| ATXN1 | ataxin 1 | 0.0195518 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0189503 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0187966 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.018575 |
| BPTF | bromodomain PHD finger transcription factor | 0.0184444 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0181168 |
| BMP6 | bone morphogenetic protein 6 | 0.0180568 |
| NDRG1 | N-myc downstream regulated 1 | 0.017879 |
| RPS8 | ribosomal protein S8 | 0.0177431 |
| RPL36 | ribosomal protein L36 | 0.0176964 |
| VEGFC | vascular endothelial growth factor C | 0.0176174 |
| RPL5 | ribosomal protein L5 | 0.0174451 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0172881 |
| HMGA2 | high mobility group AT-hook 2 | 0.0170294 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0169274 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0168499 |
| MINK1 | misshapen-like kinase 1 | 0.0167826 |
| AHR | aryl hydrocarbon receptor | 0.0167724 |
| USP47 | ubiquitin specific peptidase 47 | 0.0166535 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0165533 |
| ERBIN | erbb2 interacting protein | 0.0164618 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0161548 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0161486 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0161433 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0161371 |
| FLNA | filamin A, alpha | 0.0158311 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.015809 |
| RPS2 | ribosomal protein S2 | 0.0157891 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0157004 |
| RPS11 | ribosomal protein S11 | 0.0155924 |
| RPS29 | ribosomal protein S29 | 0.0153399 |
| EFNA5 | ephrin-A5 | 0.0151311 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0151267 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0150682 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0150123 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0149478 |
| RAD51B | RAD51 paralog B | 0.0149156 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0148522 |
| TGM2 | transglutaminase 2 | 0.0148155 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0147214 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0146767 |
| SEPTIN9 | septin 9 | 0.0146025 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.014536 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0144617 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0144061 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0143852 |
| RPL9 | ribosomal protein L9 | 0.0143385 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0143338 |
| NHSL1 | NHS-like 1 | 0.014058 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0140363 |
| GPATCH2L | G patch domain containing 2-like | 0.0139902 |
| FOXP1 | forkhead box P1 | 0.01393 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0138311 |
| GRAMD1B | GRAM domain containing 1B | 0.0137118 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.190297 |
| ANXA2 | annexin A2 | -0.162312 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161434 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.149955 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.145095 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102772 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.100129 |
| FTL | ferritin, light polypeptide | -0.0943112 |
| USP3 | ubiquitin specific peptidase 3 | -0.0880772 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0847 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0843806 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0804076 |
| ACTG1 | actin gamma 1 | -0.0798783 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0760837 |
| PGK1 | phosphoglycerate kinase 1 | -0.0723053 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0708946 |
| AHNAK | AHNAK nucleoprotein | -0.069677 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0643905 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0639097 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.063645 |
| GOLGA4 | golgin A4 | -0.0630885 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0626829 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0609981 |
| CANX | calnexin | -0.0609163 |
| PTMA | prothymosin, alpha | -0.0583381 |
| PKM | pyruvate kinase, muscle | -0.0567917 |
| CA12 | carbonic anhydrase XII | -0.0558087 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0557189 |
| UBC | ubiquitin C | -0.0546548 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0536892 |
| S100A6 | S100 calcium binding protein A6 | -0.053574 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0532983 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0528364 |
| LDHA | lactate dehydrogenase A | -0.051829 |
| TPM4 | tropomyosin 4 | -0.0516886 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0512015 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0487816 |
| RRBP1 | ribosome binding protein 1 | -0.0483134 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0481949 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0479781 |
| HELZ | helicase with zinc finger | -0.0467096 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0438119 |
| VCL | vinculin | -0.0433827 |
| SPAG9 | sperm associated antigen 9 | -0.0432003 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0430384 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0429235 |
| MAP1B | microtubule-associated protein 1B | -0.0426339 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0425578 |
| HDLBP | high density lipoprotein binding protein | -0.040596 |
| TKT | transketolase | -0.0399395 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0398053 |
| CLINT1 | clathrin interactor 1 | -0.0397753 |
| POTEF | POTE ankyrin domain family, member F | -0.0393928 |
| RIGI | RNA sensor RIG-I | -0.0389971 |
| RPS6 | ribosomal protein S6 | -0.0386969 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0383089 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0378229 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0370612 |
| SETD5 | SET domain containing 5 | -0.0370582 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0363984 |
| OSMR | oncostatin M receptor | -0.0358713 |
| TMSB4X | thymosin beta 4, X-linked | -0.0357491 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0356468 |
| RPL4 | ribosomal protein L4 | -0.0356209 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0355162 |
| RNF213 | ring finger protein 213 | -0.0353025 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0346344 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0345028 |
| SRP54 | signal recognition particle 54kDa | -0.0343749 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0339222 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0337447 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0336879 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0336471 |
| RTN4 | reticulon 4 | -0.0335369 |
| RPLP0 | ribosomal protein, large, P0 | -0.0335292 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0331173 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0327717 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0326961 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0326702 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0317559 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0314611 |
| ENO1 | enolase 1, (alpha) | -0.0312521 |
| H1-0 | H1.0 linker histone | -0.0309219 |
| KRT81 | keratin 81, type II | -0.0307199 |
| HIP1 | huntingtin interacting protein 1 | -0.0306988 |
| WDR45B | WD repeat domain 45B | -0.0304567 |
| RBM39 | RNA binding motif protein 39 | -0.0304312 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0301966 |
| SP100 | SP100 nuclear antigen | -0.0300203 |
| TMEM263 | transmembrane protein 263 | -0.0299054 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0297914 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0296272 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0295761 |
| ATG7 | autophagy related 7 | -0.0293153 |
| SBF2 | SET binding factor 2 | -0.029234 |
| RAI14 | retinoic acid induced 14 | -0.0289869 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0289346 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0287108 |
| DENND4C | DENN/MADD domain containing 4C | -0.0286134 |
| ARF1 | ADP-ribosylation factor 1 | -0.0285585 |