| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0485977 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0405488 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0372489 |
| EFNA5 | ephrin-A5 | 0.0369677 |
| PLEC | plectin | 0.0315071 |
| FMNL2 | formin-like 2 | 0.0308968 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0294761 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0291999 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.029055 |
| SMAD3 | SMAD family member 3 | 0.0286475 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0283561 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0278007 |
| BCL2L1 | BCL2-like 1 | 0.0266751 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0262348 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0260945 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0248622 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0245591 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0219517 |
| PMM2 | phosphomannomutase 2 | 0.0218705 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0218007 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0217369 |
| RUNX1 | runt-related transcription factor 1 | 0.0202983 |
| PTK2 | protein tyrosine kinase 2 | 0.0199281 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.019423 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0193805 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0192587 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.019234 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0190829 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0186601 |
| TGM2 | transglutaminase 2 | 0.0186045 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0175087 |
| FLNA | filamin A, alpha | 0.0174913 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0173786 |
| NABP1 | nucleic acid binding protein 1 | 0.0172114 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0171319 |
| SEPTIN9 | septin 9 | 0.0170173 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0169342 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0159788 |
| INTS6 | integrator complex subunit 6 | 0.0159456 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0158471 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0151128 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.014834 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0147768 |
| ATP13A3 | ATPase type 13A3 | 0.0146391 |
| SNRK | SNF related kinase | 0.0146118 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0145536 |
| FLNB | filamin B, beta | 0.0144199 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.014403 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.014373 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0141309 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0140964 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0138201 |
| CTBP2 | C-terminal binding protein 2 | 0.0136132 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0133057 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0133008 |
| APP | amyloid beta (A4) precursor protein | 0.0132831 |
| AFDN | afadin, adherens junction formation factor | 0.0132629 |
| RAB31 | RAB31, member RAS oncogene family | 0.013257 |
| GTDC1 | glycosyltransferase-like domain containing 1 | 0.0132172 |
| KLC1 | kinesin light chain 1 | 0.0132153 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0131832 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0131678 |
| TRAF3 | TNF receptor-associated factor 3 | 0.0129494 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0125746 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.012536 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.012534 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0124086 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0123292 |
| BMP6 | bone morphogenetic protein 6 | 0.0121788 |
| EFNB2 | ephrin-B2 | 0.0120931 |
| TRRAP | transformation/transcription domain-associated protein | 0.0120727 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.012048 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0119542 |
| NCKAP1 | NCK-associated protein 1 | 0.0119499 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0119434 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.011921 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0118342 |
| HPCAL1 | hippocalcin-like 1 | 0.0118294 |
| SKI | SKI proto-oncogene | 0.011781 |
| STRIP2 | striatin interacting protein 2 | 0.0114666 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0112826 |
| FUS | FUS RNA binding protein | 0.0111901 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0110147 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0106623 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0106575 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0106326 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0104335 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0102788 |
| CORO1C | coronin, actin binding protein, 1C | 0.0102603 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0102207 |
| CFAP161 | cilia and flagella associated protein 161 | 0.0101992 |
| TCF20 | transcription factor 20 (AR1) | 0.010165 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0101411 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0100399 |
| DENND5A | DENN/MADD domain containing 5A | 0.0100253 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0099644 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.00987457 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.00973757 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0096781 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.00962912 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.199124 |
| POTEF | POTE ankyrin domain family, member F | -0.175546 |
| VIM | vimentin | -0.171105 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.166871 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.163079 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.154469 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.147541 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.1348 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.129342 |
| MUC17 | mucin 17, cell surface associated | -0.124284 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.120233 |
| KLK10 | kallikrein-related peptidase 10 | -0.0997919 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0978613 |
| TXNRD1 | thioredoxin reductase 1 | -0.095044 |
| PTMA | prothymosin, alpha | -0.0929587 |
| LDHA | lactate dehydrogenase A | -0.092584 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0898253 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0866432 |
| LMO7 | LIM domain 7 | -0.0863952 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0849841 |
| UBC | ubiquitin C | -0.0849004 |
| S100A10 | S100 calcium binding protein A10 | -0.0848358 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.079512 |
| TMSB10 | thymosin beta 10 | -0.0775628 |
| RIOK3 | RIO kinase 3 | -0.0772768 |
| PGK1 | phosphoglycerate kinase 1 | -0.0748668 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0741192 |
| HMGA1 | high mobility group AT-hook 1 | -0.073702 |
| VCAN | versican | -0.071723 |
| TXNIP | thioredoxin interacting protein | -0.0709205 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.070691 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0697342 |
| EGR1 | early growth response 1 | -0.0678967 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0662852 |
| ANXA2 | annexin A2 | -0.0656551 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0653315 |
| B2M | beta-2-microglobulin | -0.0648761 |
| PERP | PERP, TP53 apoptosis effector | -0.0645116 |
| EZR | ezrin | -0.0641257 |
| S100A11 | S100 calcium binding protein A11 | -0.0638156 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0633002 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0621941 |
| DSG2 | desmoglein 2 | -0.0613225 |
| FAM107B | family with sequence similarity 107, member B | -0.0607276 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0602991 |
| ITGA6 | integrin, alpha 6 | -0.0586945 |
| TPM4 | tropomyosin 4 | -0.0577866 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0559246 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0528219 |
| LAMA4 | laminin, alpha 4 | -0.052697 |
| MXD1 | MAX dimerization protein 1 | -0.0523074 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0521441 |
| S100A6 | S100 calcium binding protein A6 | -0.051538 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0503786 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0501333 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0498562 |
| ACTG1 | actin gamma 1 | -0.0484245 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0482162 |
| TPM3 | tropomyosin 3 | -0.0479185 |
| KRT19 | keratin 19, type I | -0.0475168 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0474046 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0472205 |
| EMP1 | epithelial membrane protein 1 | -0.0469716 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0465882 |
| PKM | pyruvate kinase, muscle | -0.046509 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0464251 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0451155 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.045069 |
| FOSL1 | FOS-like antigen 1 | -0.0450007 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0441147 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0435738 |
| FERMT1 | fermitin family member 1 | -0.0435524 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0431329 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0429803 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0416153 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0414154 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0413663 |
| ENO1 | enolase 1, (alpha) | -0.0411596 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0409018 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0406052 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0403018 |
| ASPH | aspartate beta-hydroxylase | -0.0400633 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0400008 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0391337 |
| ARF4 | ADP-ribosylation factor 4 | -0.0387357 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0387285 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0386275 |
| OPTN | optineurin | -0.0383896 |
| LAMB3 | laminin, beta 3 | -0.036283 |
| RPS6 | ribosomal protein S6 | -0.0361628 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0356188 |
| RTN4 | reticulon 4 | -0.03522 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0351979 |
| GOLGA4 | golgin A4 | -0.0349705 |
| CDCP1 | CUB domain containing protein 1 | -0.0349275 |
| NPSR1 | neuropeptide S receptor 1 | -0.0346481 |
| RPL12 | ribosomal protein L12 | -0.0345099 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0344719 |
| S100A4 | S100 calcium binding protein A4 | -0.0342941 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0337998 |
