| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CLTC | clathrin, heavy chain (Hc) | 0.115141 |
| FNDC3A | fibronectin type III domain containing 3A | 0.101433 |
| VMP1 | vacuole membrane protein 1 | 0.0905401 |
| SMYD3 | SET and MYND domain containing 3 | 0.0852629 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0714735 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0707963 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0706651 |
| PRRC2C | proline-rich coiled-coil 2C | 0.070563 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0646424 |
| LDHA | lactate dehydrogenase A | 0.0642218 |
| RPL23 | ribosomal protein L23 | 0.0632124 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0585153 |
| INTS6 | integrator complex subunit 6 | 0.0567787 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0548641 |
| APP | amyloid beta (A4) precursor protein | 0.053482 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0510916 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0506745 |
| CDK12 | cyclin-dependent kinase 12 | 0.0499587 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0491235 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0475633 |
| SP100 | SP100 nuclear antigen | 0.0460427 |
| MCL1 | myeloid cell leukemia 1 | 0.0452721 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0445496 |
| KIF1A | kinesin family member 1A | 0.0437838 |
| SET | SET nuclear proto-oncogene | 0.0436211 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0432722 |
| ACTN1 | actinin, alpha 1 | 0.0416968 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0416164 |
| STK4 | serine/threonine kinase 4 | 0.0412346 |
| AHR | aryl hydrocarbon receptor | 0.0412321 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.039189 |
| EFNA5 | ephrin-A5 | 0.0391076 |
| RPS3 | ribosomal protein S3 | 0.0388658 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0384094 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0383529 |
| MED13 | mediator complex subunit 13 | 0.0375601 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0373849 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0371816 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0370728 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0367359 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0362227 |
| SGMS1 | sphingomyelin synthase 1 | 0.036162 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0355926 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0355065 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0353627 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0347802 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0347484 |
| CEP250 | centrosomal protein 250kDa | 0.03443 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0343674 |
| ENO1 | enolase 1, (alpha) | 0.0342231 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0336617 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0326842 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0319645 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0319414 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0316285 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0314407 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.031368 |
| VCP | valosin containing protein | 0.0311199 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0308664 |
| ATXN1 | ataxin 1 | 0.0306677 |
| SBF2 | SET binding factor 2 | 0.0306155 |
| NDRG1 | N-myc downstream regulated 1 | 0.0304912 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0303618 |
| NABP1 | nucleic acid binding protein 1 | 0.0303458 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0300259 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0299987 |
| ASPH | aspartate beta-hydroxylase | 0.0296987 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.029598 |
| FNBP1L | formin binding protein 1-like | 0.029452 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0292655 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0292193 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0291193 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0288772 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0286893 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0281611 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0280875 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0280217 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0279692 |
| ZNF217 | zinc finger protein 217 | 0.0279334 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0278186 |
| GPHN | gephyrin | 0.0277556 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0277332 |
| SEPTIN9 | septin 9 | 0.0276076 |
| EGFR | epidermal growth factor receptor | 0.0275742 |
| ADAR | adenosine deaminase, RNA-specific | 0.0275329 |
| MAP7 | microtubule-associated protein 7 | 0.0275154 |
| CREBBP | CREB binding protein | 0.0274508 |
| RAD51B | RAD51 paralog B | 0.0274327 |
| MYOF | myoferlin | 0.0274097 |
| KRT18 | keratin 18, type I | 0.0273179 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0272214 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0272179 |
| KRT86 | keratin 86, type II | 0.0272165 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0268286 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.0267441 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0266895 |
| PTK2 | protein tyrosine kinase 2 | 0.0266852 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0259519 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0259257 |
| ENAH | enabled homolog (Drosophila) | 0.0258307 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.175599 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.113827 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.111417 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.1044 |
| PTMA | prothymosin, alpha | -0.0954887 |
| LASP1 | LIM and SH3 protein 1 | -0.0896674 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0880077 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0826411 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0603718 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0542533 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0536194 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0511246 |
| FADS2 | fatty acid desaturase 2 | -0.0483499 |
| GRB7 | growth factor receptor-bound protein 7 | -0.047633 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0459556 |
| POTEF | POTE ankyrin domain family, member F | -0.0451007 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0441007 |
| RPL19 | ribosomal protein L19 | -0.0409336 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0408535 |
| TMSB4X | thymosin beta 4, X-linked | -0.0384092 |
| ACACA | acetyl-CoA carboxylase alpha | -0.037973 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0378959 |
| FDPS | farnesyl diphosphate synthase | -0.0373812 |
| FASN | fatty acid synthase | -0.0367883 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0362799 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0361175 |
| RPL35A | ribosomal protein L35a | -0.0353204 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0344923 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0341123 |
| TMSB10 | thymosin beta 10 | -0.0327481 |
| KAZN | kazrin, periplakin interacting protein | -0.0318995 |
| ACTG1 | actin gamma 1 | -0.0318727 |
| CCND1 | cyclin D1 | -0.0315945 |
| CD46 | CD46 molecule, complement regulatory protein | -0.031262 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0303671 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0301337 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0295153 |
| CCNL1 | cyclin L1 | -0.0285289 |
| CD24 | CD24 molecule | -0.0281579 |
| TMEM165 | transmembrane protein 165 | -0.0278488 |
| INSIG1 | insulin induced gene 1 | -0.0277524 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0264951 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0263798 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -0.0263235 |
| OSMR | oncostatin M receptor | -0.025472 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0248535 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0247856 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0247348 |
| RPS6 | ribosomal protein S6 | -0.0246324 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0246082 |
| TMEM123 | transmembrane protein 123 | -0.0244205 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0242735 |
| DSTN | destrin (actin depolymerizing factor) | -0.0236347 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0236166 |
| GOLGA4 | golgin A4 | -0.0234873 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0234653 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0230813 |
| UBC | ubiquitin C | -0.0226713 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0226287 |
| S100A8 | S100 calcium binding protein A8 | -0.0225083 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0222751 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0218335 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0217801 |
| S100A14 | S100 calcium binding protein A14 | -0.021497 |
| GSE1 | Gse1 coiled-coil protein | -0.0213891 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0213482 |
| PERP | PERP, TP53 apoptosis effector | -0.0208693 |
| S100A6 | S100 calcium binding protein A6 | -0.0208069 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0207013 |
| TPM4 | tropomyosin 4 | -0.0206716 |
| TPCN1 | two pore segment channel 1 | -0.0204093 |
| TMEM41B | transmembrane protein 41B | -0.0202792 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0200805 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0197833 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0197322 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0197038 |
| CCNI | cyclin I | -0.0196919 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0194122 |
| SQLE | squalene epoxidase | -0.0193653 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0193416 |
| SRP54 | signal recognition particle 54kDa | -0.0189157 |
| ZNF652 | zinc finger protein 652 | -0.0186769 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0185415 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0184908 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0184111 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | -0.0183719 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0181331 |
| TNS3 | tensin 3 | -0.0179021 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0178271 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.0176309 |
| HMGB1 | high mobility group box 1 | -0.0174903 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0171956 |
| KIF16B | kinesin family member 16B | -0.0170083 |
| ANKRD30A | ankyrin repeat domain 30A | -0.0169408 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0169168 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | -0.0169046 |
| MVD | mevalonate (diphospho) decarboxylase | -0.016867 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0166555 |
| IER3 | immediate early response 3 | -0.0166252 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.016619 |
