| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.326961 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.108931 |
| ACTN1 | actinin, alpha 1 | 0.0807113 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0779195 |
| FMN1 | formin 1 | 0.075936 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0749922 |
| FN1 | fibronectin 1 | 0.0749016 |
| NDRG1 | N-myc downstream regulated 1 | 0.0704431 |
| MT2A | metallothionein 2A | 0.0663131 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0619179 |
| HLA-B | major histocompatibility complex, class I, B | 0.061668 |
| FMNL2 | formin-like 2 | 0.0604575 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0602722 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0599985 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0597001 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0533522 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0530719 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0523547 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0509685 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0484553 |
| GPC6 | glypican 6 | 0.0475079 |
| SFTPA2 | surfactant protein A2 | 0.0472638 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0469037 |
| AFDN | afadin, adherens junction formation factor | 0.0450068 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0447553 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0430916 |
| MCL1 | myeloid cell leukemia 1 | 0.0430286 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0428577 |
| FUS | FUS RNA binding protein | 0.0428019 |
| RPS12 | ribosomal protein S12 | 0.0414425 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0405517 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0398939 |
| RPL37A | ribosomal protein L37a | 0.0398524 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0387308 |
| EGR1 | early growth response 1 | 0.0385252 |
| TLE4 | transducin-like enhancer of split 4 | 0.0378985 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0375928 |
| RPS3 | ribosomal protein S3 | 0.0373491 |
| FLNB | filamin B, beta | 0.0364265 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0363626 |
| SETBP1 | SET binding protein 1 | 0.0359422 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0355444 |
| SMYD3 | SET and MYND domain containing 3 | 0.035471 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0346075 |
| FRMD4A | FERM domain containing 4A | 0.0342249 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0329463 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0328759 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0326565 |
| TMSB10 | thymosin beta 10 | 0.0323841 |
| MORF4L2 | mortality factor 4 like 2 | 0.032381 |
| HMGA2 | high mobility group AT-hook 2 | 0.0317118 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0309669 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0308677 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0305806 |
| APP | amyloid beta (A4) precursor protein | 0.0302886 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0294291 |
| RPS8 | ribosomal protein S8 | 0.0291498 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0288733 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0287835 |
| PAX3 | paired box 3 | 0.0282138 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0280638 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0276952 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0275691 |
| BPTF | bromodomain PHD finger transcription factor | 0.027467 |
| RPL23 | ribosomal protein L23 | 0.0270143 |
| VCL | vinculin | 0.0269368 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0268957 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0262579 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0260826 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0260772 |
| RPL36 | ribosomal protein L36 | 0.0259278 |
| JUN | jun proto-oncogene | 0.0259122 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0256656 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0255207 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0253961 |
| RAD51B | RAD51 paralog B | 0.0253933 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0252936 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.025248 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0251717 |
| MYO1E | myosin IE | 0.0248278 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0247706 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0247614 |
| RPL26 | ribosomal protein L26 | 0.0244507 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0239418 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0235976 |
| PCDH7 | protocadherin 7 | 0.0234957 |
| INTS6 | integrator complex subunit 6 | 0.0233361 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0232342 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0231277 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.023034 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0228449 |
| RASA3 | RAS p21 protein activator 3 | 0.0228444 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0227806 |
| UTRN | utrophin | 0.0227444 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0226743 |
| ENO1 | enolase 1, (alpha) | 0.0223952 |
| WDR1 | WD repeat domain 1 | 0.0223529 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.022346 |
| EZR | ezrin | 0.022239 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0221376 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.221261 |
| VGF | VGF nerve growth factor inducible | -0.20871 |
| DCT | dopachrome tautomerase | -0.121541 |
| CD109 | CD109 molecule | -0.0890482 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0695895 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0649173 |
| POTEF | POTE ankyrin domain family, member F | -0.0629527 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0588917 |
| PGK1 | phosphoglycerate kinase 1 | -0.0572433 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0562577 |
| NLGN1 | neuroligin 1 | -0.0542469 |
| TAGLN2 | transgelin 2 | -0.0510299 |
| PLIN2 | perilipin 2 | -0.0480322 |
| PDE10A | phosphodiesterase 10A | -0.047404 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0473482 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0470853 |
| NBAS | neuroblastoma amplified sequence | -0.046671 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0450936 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0441642 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0438504 |
| S100A6 | S100 calcium binding protein A6 | -0.0435381 |
| SETD5 | SET domain containing 5 | -0.0421994 |
| CENPF | centromere protein F, 350/400kDa | -0.0421868 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0419328 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0413587 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.040347 |
| RFX7 | regulatory factor X, 7 | -0.0403377 |
| CALD1 | caldesmon 1 | -0.0389198 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0379216 |
| PKM | pyruvate kinase, muscle | -0.0364881 |
| GDF15 | growth differentiation factor 15 | -0.0364606 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0364012 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | -0.0354714 |
| CTSD | cathepsin D | -0.0349352 |
| GOLGA4 | golgin A4 | -0.0342548 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0341675 |
| NAV3 | neuron navigator 3 | -0.0326163 |
| FOSL1 | FOS-like antigen 1 | -0.03258 |
| POM121 | POM121 transmembrane nucleoporin | -0.0311052 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0307712 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0306986 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0305376 |
| SRPK2 | SRSF protein kinase 2 | -0.0305233 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0303853 |
| PTMS | parathymosin | -0.0303809 |
| PHF21A | PHD finger protein 21A | -0.0301891 |
| TMEM123 | transmembrane protein 123 | -0.0297521 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0292661 |
| INSIG2 | insulin induced gene 2 | -0.0292487 |
| TRIM2 | tripartite motif containing 2 | -0.0288815 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0287543 |
| RNF145 | ring finger protein 145 | -0.0285533 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0283848 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0281748 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0279769 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0276143 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0273974 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0270031 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0267391 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0261752 |
| CDK14 | cyclin-dependent kinase 14 | -0.0260848 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0260801 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0251995 |
| INSIG1 | insulin induced gene 1 | -0.0247641 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0247417 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0247013 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.024496 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0244417 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0244123 |
| MT1X | metallothionein 1X | -0.0243254 |
| MYO10 | myosin X | -0.0241961 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0239584 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0237037 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0237005 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0232822 |
| ZNF638 | zinc finger protein 638 | -0.0229078 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.022885 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0227199 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0224672 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0224585 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0222157 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0219681 |
| GHR | growth hormone receptor | -0.0219483 |
| GNAS | GNAS complex locus | -0.0218798 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -0.0218798 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0218209 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0217628 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0217581 |
| CCNL1 | cyclin L1 | -0.021689 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0216711 |
| WDR45B | WD repeat domain 45B | -0.020803 |
| OXR1 | oxidation resistance 1 | -0.0207468 |
| CYGB | cytoglobin | -0.0206705 |
| ACLY | ATP citrate lyase | -0.0206249 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0206065 |
| RBM33 | RNA binding motif protein 33 | -0.0206049 |
| CDC73 | cell division cycle 73 | -0.0205769 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | -0.0203266 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0202865 |
| CDK19 | cyclin-dependent kinase 19 | -0.0202697 |
