| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.172875 |
| APP | amyloid beta (A4) precursor protein | 0.103472 |
| MYO1E | myosin IE | 0.0880257 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0843839 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0838231 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0804933 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0753867 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0752674 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0746434 |
| TGM2 | transglutaminase 2 | 0.0713935 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0696925 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0691787 |
| FAM3C | family with sequence similarity 3, member C | 0.0640531 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0627087 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0627056 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.061896 |
| LCN2 | lipocalin 2 | 0.0611227 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0604699 |
| EFNA5 | ephrin-A5 | 0.0577605 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0574898 |
| HDAC9 | histone deacetylase 9 | 0.0571554 |
| LDHA | lactate dehydrogenase A | 0.0561661 |
| MYOF | myoferlin | 0.0536304 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0526345 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0514599 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0509439 |
| BCL2L1 | BCL2-like 1 | 0.0505557 |
| BICC1 | BicC family RNA binding protein 1 | 0.0500822 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0500056 |
| KRT19 | keratin 19, type I | 0.0473669 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.046755 |
| SGMS2 | sphingomyelin synthase 2 | 0.046678 |
| NRG3 | neuregulin 3 | 0.0465868 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0459409 |
| TMC5 | transmembrane channel-like 5 | 0.04532 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0443022 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.044139 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0440585 |
| TGFB2 | transforming growth factor, beta 2 | 0.0433401 |
| NDRG1 | N-myc downstream regulated 1 | 0.0433265 |
| NRP1 | neuropilin 1 | 0.0428909 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0426489 |
| FUS | FUS RNA binding protein | 0.0416751 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0416022 |
| NTN4 | netrin 4 | 0.0414776 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0390392 |
| KYNU | kynureninase | 0.0389438 |
| SEPTIN9 | septin 9 | 0.038241 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0379826 |
| JAK1 | Janus kinase 1 | 0.0373174 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0366893 |
| EHF | ets homologous factor | 0.0366029 |
| RPS4X | ribosomal protein S4, X-linked | 0.0365187 |
| IL6ST | interleukin 6 signal transducer | 0.0363851 |
| TMEM51 | transmembrane protein 51 | 0.0360176 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0359972 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0356719 |
| AREG | amphiregulin | 0.0356424 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0351861 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0350429 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0345951 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0345489 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0343356 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0337689 |
| RPS3 | ribosomal protein S3 | 0.0335509 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0332469 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0331341 |
| HKDC1 | hexokinase domain containing 1 | 0.0328635 |
| MORF4L2 | mortality factor 4 like 2 | 0.0322641 |
| CANX | calnexin | 0.0321518 |
| ENO1 | enolase 1, (alpha) | 0.0319768 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0319442 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0315205 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0313392 |
| SFTPA2 | surfactant protein A2 | 0.0312905 |
| FOXP1 | forkhead box P1 | 0.0310066 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0309434 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.030908 |
| CMIP | c-Maf inducing protein | 0.0308111 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0307282 |
| KIF13B | kinesin family member 13B | 0.0306734 |
| FHL2 | four and a half LIM domains 2 | 0.0302386 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0294305 |
| PHF3 | PHD finger protein 3 | 0.0293726 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0292762 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.028957 |
| CD2AP | CD2-associated protein | 0.0289533 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.028933 |
| LMO7 | LIM domain 7 | 0.028523 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0284127 |
| RPS12 | ribosomal protein S12 | 0.0281586 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0281035 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0279745 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0278018 |
| FAM107B | family with sequence similarity 107, member B | 0.0277086 |
| FAAH2 | fatty acid amide hydrolase 2 | 0.027427 |
| GOLGB1 | golgin B1 | 0.0273345 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0269591 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0267261 |
| NOTCH2 | notch 2 | 0.0263805 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.138276 |
| DTNA | dystrobrevin, alpha | -0.103595 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.089759 |
| POTEF | POTE ankyrin domain family, member F | -0.0859203 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0817623 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0787721 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0769274 |
| LAMB3 | laminin, beta 3 | -0.0672384 |
| RCOR1 | REST corepressor 1 | -0.0660041 |
| LAMC2 | laminin, gamma 2 | -0.0656705 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0651642 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0605382 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0600846 |
| RTN4 | reticulon 4 | -0.060031 |
| MEF2A | myocyte enhancer factor 2A | -0.0599868 |
| PTMA | prothymosin, alpha | -0.0567328 |
| JUP | junction plakoglobin | -0.0557205 |
| CP | ceruloplasmin (ferroxidase) | -0.0550024 |
| ANXA2 | annexin A2 | -0.0548659 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0538337 |
| CCNY | cyclin Y | -0.0519164 |
| AGRN | agrin | -0.0506326 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0503065 |
| FAM13A | family with sequence similarity 13, member A | -0.0501794 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0492615 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0486913 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0475926 |
| ACTG1 | actin gamma 1 | -0.0475292 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0467143 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.046572 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.04365 |
| NCKAP5 | NCK-associated protein 5 | -0.0431431 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0418576 |
| GRB10 | growth factor receptor-bound protein 10 | -0.041573 |
| FOSL1 | FOS-like antigen 1 | -0.0414844 |
| LAMA5 | laminin, alpha 5 | -0.0411907 |
| VEGFA | vascular endothelial growth factor A | -0.0409138 |
| TAPBP | TAP binding protein (tapasin) | -0.0400539 |
| PARD3 | par-3 family cell polarity regulator | -0.039844 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0395067 |
| MAP1B | microtubule-associated protein 1B | -0.0393169 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.039043 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0389371 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.038848 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.038776 |
| RBM39 | RNA binding motif protein 39 | -0.0386836 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0385671 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0385479 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.038326 |
| GNAS | GNAS complex locus | -0.0380088 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0371733 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0368737 |
| TMEM165 | transmembrane protein 165 | -0.0368242 |
| ACTN4 | actinin, alpha 4 | -0.0366395 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0365523 |
| TMSB10 | thymosin beta 10 | -0.0364694 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0358907 |
| MCU | mitochondrial calcium uniporter | -0.0358896 |
| CLIC4 | chloride intracellular channel 4 | -0.0353483 |
| PLS3 | plastin 3 | -0.0351931 |
| ITGA6 | integrin, alpha 6 | -0.0350333 |
| MT1X | metallothionein 1X | -0.0349302 |
| CD47 | CD47 molecule | -0.0349294 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.034814 |
| TPM4 | tropomyosin 4 | -0.0343376 |
| SPAG9 | sperm associated antigen 9 | -0.033026 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0329628 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0324414 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0322682 |
| DIAPH1 | diaphanous-related formin 1 | -0.0320027 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0318176 |
| INSIG2 | insulin induced gene 2 | -0.030873 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0307032 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0305883 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0305396 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.030469 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.0303971 |
| HMGA1 | high mobility group AT-hook 1 | -0.0303701 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.030106 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0300601 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0300421 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0299613 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0299048 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.029447 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.029371 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0289503 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0286905 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0286249 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0285873 |
| COPA | coatomer protein complex, subunit alpha | -0.0285868 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0283965 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0282831 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0282484 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0281148 |
| ZNF292 | zinc finger protein 292 | -0.0280291 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0278611 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0278186 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0277896 |
| AHNAK | AHNAK nucleoprotein | -0.0275498 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0275097 |
