| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.310868 |
| FMN1 | formin 1 | 0.117208 |
| VCL | vinculin | 0.109094 |
| TLE4 | transducin-like enhancer of split 4 | 0.102364 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0969225 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.095537 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0933931 |
| DST | dystonin | 0.0651144 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0650766 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0592485 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0589413 |
| PLPP1 | phospholipid phosphatase 1 | 0.0588931 |
| EGR1 | early growth response 1 | 0.0585267 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0569837 |
| PLAT | plasminogen activator, tissue | 0.0548319 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0538959 |
| VMP1 | vacuole membrane protein 1 | 0.0537725 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.052453 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0511087 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0510009 |
| GLCCI1 | glucocorticoid induced 1 | 0.0507883 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0454604 |
| MEIS2 | Meis homeobox 2 | 0.045078 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.04394 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0382394 |
| SIK2 | salt-inducible kinase 2 | 0.0379489 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0372275 |
| FN1 | fibronectin 1 | 0.0369734 |
| FERMT2 | fermitin family member 2 | 0.0369305 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0351749 |
| FNBP1 | formin binding protein 1 | 0.0347928 |
| RIGI | RNA sensor RIG-I | 0.0340704 |
| FAM107B | family with sequence similarity 107, member B | 0.0340333 |
| KLHL13 | kelch-like family member 13 | 0.0334937 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0333706 |
| STK38L | serine/threonine kinase 38 like | 0.0331966 |
| BPTF | bromodomain PHD finger transcription factor | 0.032919 |
| HOMER1 | homer scaffolding protein 1 | 0.0328147 |
| MYO1E | myosin IE | 0.0320765 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0314537 |
| PDE10A | phosphodiesterase 10A | 0.0313201 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0308631 |
| STC1 | stanniocalcin 1 | 0.0307023 |
| RGS4 | regulator of G-protein signaling 4 | 0.0301704 |
| ACTN1 | actinin, alpha 1 | 0.0301534 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0284799 |
| DIAPH2 | diaphanous-related formin 2 | 0.0283349 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0281215 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0270984 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0266202 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0265779 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0264741 |
| INTS6 | integrator complex subunit 6 | 0.0263757 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.024948 |
| ATM | ATM serine/threonine kinase | 0.0246088 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.024519 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0243711 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0243533 |
| SFTPA2 | surfactant protein A2 | 0.0243 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0242475 |
| IRS1 | insulin receptor substrate 1 | 0.0242224 |
| THBS1 | thrombospondin 1 | 0.0241482 |
| GAB2 | GRB2-associated binding protein 2 | 0.0237788 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0233538 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0231737 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0228067 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.022786 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0226593 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0224971 |
| MCL1 | myeloid cell leukemia 1 | 0.0224486 |
| DGKH | diacylglycerol kinase, eta | 0.022185 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0216404 |
| CTSB | cathepsin B | 0.021554 |
| DNMBP | dynamin binding protein | 0.021458 |
| HDX | highly divergent homeobox | 0.0214072 |
| RAD51B | RAD51 paralog B | 0.021139 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0210931 |
| HDAC4 | histone deacetylase 4 | 0.021074 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0207565 |
| PCDH7 | protocadherin 7 | 0.0206928 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0204936 |
| CEP112 | centrosomal protein 112kDa | 0.0204299 |
| ITGA1 | integrin, alpha 1 | 0.0203663 |
| ITPKB | inositol-trisphosphate 3-kinase B | 0.0203608 |
| DUSP10 | dual specificity phosphatase 10 | 0.0203001 |
| SETBP1 | SET binding protein 1 | 0.0202494 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0202312 |
| VEGFA | vascular endothelial growth factor A | 0.0201252 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.020094 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0200768 |
| JUN | jun proto-oncogene | 0.0200668 |
| MACROD2 | MACRO domain containing 2 | 0.0198057 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0197741 |
| SYT1 | synaptotagmin I | 0.01964 |
| RPS4X | ribosomal protein S4, X-linked | 0.0193465 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0193238 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0191694 |
| FRMD6 | FERM domain containing 6 | 0.0190868 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0190039 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0189453 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.387188 |
| NRG1 | neuregulin 1 | -0.231581 |
| LPIN1 | lipin 1 | -0.0868591 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0828612 |
| PTMA | prothymosin, alpha | -0.0740448 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0672033 |
| TRIB2 | tribbles pseudokinase 2 | -0.0630101 |
| CADM2 | cell adhesion molecule 2 | -0.0588928 |
| COL1A1 | collagen, type I, alpha 1 | -0.0541115 |
| VIM | vimentin | -0.0540374 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0463371 |
| AHNAK | AHNAK nucleoprotein | -0.0457392 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0457122 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0451274 |
| RBM25 | RNA binding motif protein 25 | -0.0441146 |
| GOLGA4 | golgin A4 | -0.0440746 |
| MAP1B | microtubule-associated protein 1B | -0.0416727 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0412817 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0406639 |
| DTNA | dystrobrevin, alpha | -0.0388628 |
| PTK2 | protein tyrosine kinase 2 | -0.0382838 |
| SPAG9 | sperm associated antigen 9 | -0.0379382 |
| RPL23 | ribosomal protein L23 | -0.0379276 |
| QKI | QKI, KH domain containing, RNA binding | -0.0373076 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0354698 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0349167 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.034715 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0339032 |
| TMSB10 | thymosin beta 10 | -0.0336864 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0334052 |
| RPS6 | ribosomal protein S6 | -0.0329963 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0327326 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0326422 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.032586 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0321525 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0320509 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0317645 |
| WDR45B | WD repeat domain 45B | -0.0317542 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0315491 |
| HMGB2 | high mobility group box 2 | -0.0315148 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0313616 |
| COPA | coatomer protein complex, subunit alpha | -0.0312775 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0307046 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0303977 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0296241 |
| GPC5 | glypican 5 | -0.0293499 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.029182 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0286426 |
| HELZ | helicase with zinc finger | -0.0282194 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.028116 |
| RPL19 | ribosomal protein L19 | -0.0277234 |
| FOXK2 | forkhead box K2 | -0.0275083 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.027504 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0274234 |
| PKM | pyruvate kinase, muscle | -0.027338 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0268516 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0266699 |
| CADM1 | cell adhesion molecule 1 | -0.0265932 |
| TENM2 | teneurin transmembrane protein 2 | -0.0264421 |
| KLHL5 | kelch-like family member 5 | -0.0262339 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0261501 |
| USP3 | ubiquitin specific peptidase 3 | -0.0258667 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0258385 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.025837 |
| COL3A1 | collagen, type III, alpha 1 | -0.0257556 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0254329 |
| H3-3B | H3.3 histone B | -0.0253492 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0252717 |
| CDC27 | cell division cycle 27 | -0.0252216 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0251824 |
| HDLBP | high density lipoprotein binding protein | -0.0250837 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0250164 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.024859 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0246172 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0245642 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0244293 |
| XPO1 | exportin 1 | -0.0244091 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0243661 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0242794 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0242522 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0240955 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0240465 |
| CCND1 | cyclin D1 | -0.0239443 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0239396 |
| SETD5 | SET domain containing 5 | -0.0238704 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0237492 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0236756 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0235104 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0234614 |
| CDH13 | cadherin 13 | -0.0234382 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0234337 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0233039 |
| NPAS3 | neuronal PAS domain protein 3 | -0.023145 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0229695 |
| NEMF | nuclear export mediator factor | -0.0228923 |
| PCDH9 | protocadherin 9 | -0.0228587 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0226903 |
| CUX1 | cut-like homeobox 1 | -0.0224907 |
| COPS2 | COP9 signalosome subunit 2 | -0.0224629 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0224258 |
