| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.26754 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.142612 |
| SMAD3 | SMAD family member 3 | 0.136052 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.13512 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.134382 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.124105 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.120119 |
| MYO1E | myosin IE | 0.118322 |
| LCN2 | lipocalin 2 | 0.112401 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.107862 |
| AREG | amphiregulin | 0.0961384 |
| INTS6 | integrator complex subunit 6 | 0.0909183 |
| EFNB2 | ephrin-B2 | 0.0893424 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.089014 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0804907 |
| TSC22D1 | TSC22 domain family, member 1 | 0.069853 |
| VCL | vinculin | 0.0685461 |
| TMC5 | transmembrane channel-like 5 | 0.068356 |
| ANXA2 | annexin A2 | 0.0671563 |
| BCL2L1 | BCL2-like 1 | 0.0668756 |
| TJP1 | tight junction protein 1 | 0.0642724 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0640526 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0626467 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0615324 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.060775 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0604645 |
| ASPH | aspartate beta-hydroxylase | 0.0589992 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0563667 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0553646 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.053576 |
| ERBIN | erbb2 interacting protein | 0.0527664 |
| RNF213 | ring finger protein 213 | 0.0500338 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0494737 |
| EGR1 | early growth response 1 | 0.0488391 |
| EZR | ezrin | 0.0484182 |
| DST | dystonin | 0.0471943 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0438264 |
| SLK | STE20-like kinase | 0.0424972 |
| SEPTIN9 | septin 9 | 0.0423494 |
| YAP1 | Yes-associated protein 1 | 0.0414454 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0413193 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0403467 |
| KYNU | kynureninase | 0.0403076 |
| VMP1 | vacuole membrane protein 1 | 0.0401138 |
| RBM47 | RNA binding motif protein 47 | 0.0393915 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0392774 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0388197 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0384031 |
| MT2A | metallothionein 2A | 0.0376255 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0365462 |
| LIPH | lipase, member H | 0.0360995 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0357567 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0357497 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0353132 |
| HKDC1 | hexokinase domain containing 1 | 0.0352814 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0342768 |
| EREG | epiregulin | 0.0342379 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0341838 |
| NABP1 | nucleic acid binding protein 1 | 0.0337254 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0334594 |
| MAP7 | microtubule-associated protein 7 | 0.0327928 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0323149 |
| SPAG9 | sperm associated antigen 9 | 0.0317475 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0317195 |
| FNIP2 | folliculin interacting protein 2 | 0.0316694 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0314031 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0310835 |
| ETV6 | ets variant 6 | 0.0303272 |
| DUSP10 | dual specificity phosphatase 10 | 0.030323 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0301666 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0296474 |
| LIMA1 | LIM domain and actin binding 1 | 0.0295211 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0294953 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0294605 |
| TOB1 | transducer of ERBB2, 1 | 0.0294301 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0294123 |
| TOX3 | TOX high mobility group box family member 3 | 0.0292412 |
| FHL2 | four and a half LIM domains 2 | 0.0291951 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0288047 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0288042 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.028333 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.028142 |
| RPL23 | ribosomal protein L23 | 0.0281023 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0280998 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0277923 |
| KLF6 | Kruppel-like factor 6 | 0.0277277 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0275761 |
| MCL1 | myeloid cell leukemia 1 | 0.027416 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0274087 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0273251 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0272515 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.027046 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0270196 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0269728 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0268733 |
| ZNF292 | zinc finger protein 292 | 0.0267817 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0265821 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0264823 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0262756 |
| PRSS22 | protease, serine, 22 | 0.0259322 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LYZ | lysozyme | -0.107923 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.107652 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.105999 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102884 |
| PTMA | prothymosin, alpha | -0.075365 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.072345 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0718052 |
| PHF3 | PHD finger protein 3 | -0.0696244 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0674748 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0670385 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.065327 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0649713 |
| H1-0 | H1.0 linker histone | -0.059273 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0558449 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0556368 |
| AHI1 | Abelson helper integration site 1 | -0.053205 |
| NPSR1 | neuropeptide S receptor 1 | -0.0529879 |
| TXNIP | thioredoxin interacting protein | -0.0481697 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0477578 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0451941 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0448919 |
| CANX | calnexin | -0.0443191 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0422611 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0422574 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0407451 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0397927 |
| HDLBP | high density lipoprotein binding protein | -0.0387792 |
| RBM39 | RNA binding motif protein 39 | -0.0378077 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0355317 |
| PTEN | phosphatase and tensin homolog | -0.0351084 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0349898 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0349373 |
| DIAPH3 | diaphanous-related formin 3 | -0.0347049 |
| HLA-E | major histocompatibility complex, class I, E | -0.0337314 |
| GOLGB1 | golgin B1 | -0.033377 |
| EPCAM | epithelial cell adhesion molecule | -0.0324686 |
| XAF1 | XIAP associated factor 1 | -0.0322803 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0318495 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.029982 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0294598 |
| S100A6 | S100 calcium binding protein A6 | -0.0294429 |
| SEC24D | SEC24 family member D | -0.0294417 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0290863 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0287198 |
| RRBP1 | ribosome binding protein 1 | -0.0286005 |
| BRCA2 | breast cancer 2, early onset | -0.0284117 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0283561 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0281028 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0278015 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0276767 |
| TFRC | transferrin receptor | -0.0274521 |
| ANXA4 | annexin A4 | -0.0270584 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0268903 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0266989 |
| HBS1L | HBS1-like translational GTPase | -0.0265695 |
| SMC4 | structural maintenance of chromosomes 4 | -0.026396 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0263884 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0262637 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0262482 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0261764 |
| EPHB2 | EPH receptor B2 | -0.0261419 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.025727 |
| RNF149 | ring finger protein 149 | -0.0249311 |
| COG6 | component of oligomeric golgi complex 6 | -0.0247819 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0247341 |
| APOL6 | apolipoprotein L, 6 | -0.0247053 |
| HMGB1 | high mobility group box 1 | -0.0246422 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.024595 |
| UBAC2 | UBA domain containing 2 | -0.0244167 |
| GNAS | GNAS complex locus | -0.0240539 |
| KPNB1 | karyopherin (importin) beta 1 | -0.023924 |
| UBE3A | ubiquitin protein ligase E3A | -0.0238666 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0232277 |
| CCDC146 | coiled-coil domain containing 146 | -0.022998 |
| RNF43 | ring finger protein 43 | -0.0229266 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.022908 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0226957 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0222083 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0221059 |
| MKI67 | marker of proliferation Ki-67 | -0.0220521 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0219608 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0218561 |
| TPM4 | tropomyosin 4 | -0.0218467 |
| SSH2 | slingshot protein phosphatase 2 | -0.0217563 |
| APOL1 | apolipoprotein L, 1 | -0.0215337 |
| KLHL24 | kelch-like family member 24 | -0.021355 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.021311 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0211639 |
| GRAMD2B | GRAM domain containing 2B | -0.0211153 |
| LAP3 | leucine aminopeptidase 3 | -0.0209636 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0208289 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0207632 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0207276 |
| WDR45B | WD repeat domain 45B | -0.0207209 |
| HM13 | histocompatibility (minor) 13 | -0.0207165 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.020405 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0203562 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0203106 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.020283 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.020168 |
