| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.165552 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0620992 |
| EZR | ezrin | 0.0514308 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0434872 |
| PCBP2 | poly(rC) binding protein 2 | 0.0430542 |
| FTL | ferritin, light polypeptide | 0.0406454 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0399712 |
| JUN | jun proto-oncogene | 0.038096 |
| BCL2L1 | BCL2-like 1 | 0.0369737 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0360665 |
| RPS3 | ribosomal protein S3 | 0.035282 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0339702 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0335656 |
| TJP1 | tight junction protein 1 | 0.0331936 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.033171 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0312268 |
| VMP1 | vacuole membrane protein 1 | 0.029723 |
| MT2A | metallothionein 2A | 0.0287115 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0286064 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0284425 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0275554 |
| LDHA | lactate dehydrogenase A | 0.0270806 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0263358 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0262083 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0246761 |
| VIM | vimentin | 0.0231264 |
| MORF4L2 | mortality factor 4 like 2 | 0.022971 |
| SPAG9 | sperm associated antigen 9 | 0.022905 |
| FLNA | filamin A, alpha | 0.0227213 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0226234 |
| CEP290 | centrosomal protein 290kDa | 0.02226 |
| EXOC6B | exocyst complex component 6B | 0.0217045 |
| SFTPA2 | surfactant protein A2 | 0.0210882 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0210342 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0204547 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0203541 |
| MYO6 | myosin VI | 0.0201811 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0200543 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0197942 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0197595 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0194702 |
| ABI1 | abl-interactor 1 | 0.0193844 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0192406 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0191128 |
| WDR41 | WD repeat domain 41 | 0.0190061 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0186957 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0186255 |
| MACROD2 | MACRO domain containing 2 | 0.0185029 |
| ATXN7 | ataxin 7 | 0.0184031 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0183134 |
| RPL26 | ribosomal protein L26 | 0.0181679 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0181029 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0178786 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.017687 |
| RPS12 | ribosomal protein S12 | 0.0175874 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0175388 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0174392 |
| KRT18 | keratin 18, type I | 0.0172295 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0171732 |
| IER2 | immediate early response 2 | 0.0171549 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0170822 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.016969 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0168479 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.016844 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0168168 |
| CALU | calumenin | 0.0164704 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0164384 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0163147 |
| FBXO42 | F-box protein 42 | 0.0162869 |
| KLF6 | Kruppel-like factor 6 | 0.0162575 |
| RYBP | RING1 and YY1 binding protein | 0.0162255 |
| HLA-B | major histocompatibility complex, class I, B | 0.0161632 |
| CCDC47 | coiled-coil domain containing 47 | 0.0161182 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0160931 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0160577 |
| KIF5B | kinesin family member 5B | 0.015942 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.01594 |
| ACTN1 | actinin, alpha 1 | 0.0158716 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0158587 |
| NUP58 | nucleoporin 58 | 0.0158467 |
| SON | SON DNA binding protein | 0.0158252 |
| CD44 | CD44 molecule (Indian blood group) | 0.0158081 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0157907 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0155479 |
| STK4 | serine/threonine kinase 4 | 0.0155207 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0154943 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0154579 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0153813 |
| CYTH1 | cytohesin 1 | 0.0153689 |
| PCDH7 | protocadherin 7 | 0.0153572 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.015339 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0152949 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0152846 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0151356 |
| OGA | O-GlcNAcase | 0.014997 |
| MORF4L1 | mortality factor 4 like 1 | 0.0149594 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0148245 |
| CCNC | cyclin C | 0.0148168 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0147379 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0146951 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.284008 |
| FAT1 | FAT atypical cadherin 1 | -0.25409 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.197648 |
| NDRG1 | N-myc downstream regulated 1 | -0.197548 |
| RPS6 | ribosomal protein S6 | -0.103296 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0912911 |
| TMSB10 | thymosin beta 10 | -0.0862191 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0832103 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0790709 |
| RAD51B | RAD51 paralog B | -0.0761745 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0743575 |
| FHIT | fragile histidine triad | -0.0721913 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0698005 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0695638 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0685613 |
| AHNAK | AHNAK nucleoprotein | -0.0649422 |
| MSI2 | musashi RNA-binding protein 2 | -0.0587053 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0584268 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0583509 |
| SERINC5 | serine incorporator 5 | -0.0576109 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0568538 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0560177 |
| RPL35A | ribosomal protein L35a | -0.0542616 |
| HMGA2 | high mobility group AT-hook 2 | -0.0539706 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0537484 |
| TUBA1B | tubulin, alpha 1b | -0.0532304 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0523259 |
| MED13L | mediator complex subunit 13-like | -0.0505739 |
| PKM | pyruvate kinase, muscle | -0.0501014 |
| PGK1 | phosphoglycerate kinase 1 | -0.04918 |
| WWOX | WW domain containing oxidoreductase | -0.04813 |
| CTBP2 | C-terminal binding protein 2 | -0.047837 |
| POTEF | POTE ankyrin domain family, member F | -0.0476634 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0474316 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0473225 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0463912 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0458875 |
| PFN1 | profilin 1 | -0.044408 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0435577 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0430922 |
| ZNF292 | zinc finger protein 292 | -0.042945 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0429115 |
| KRT8 | keratin 8, type II | -0.0428616 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0424034 |
| VEGFA | vascular endothelial growth factor A | -0.042039 |
| CCND1 | cyclin D1 | -0.0419593 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0418335 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0413189 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0407127 |
| HELLS | helicase, lymphoid-specific | -0.040627 |
| PTK2 | protein tyrosine kinase 2 | -0.0399072 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0399068 |
| MEF2A | myocyte enhancer factor 2A | -0.0394787 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.039164 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0390345 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0389438 |
| S100A9 | S100 calcium binding protein A9 | -0.0387623 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0386388 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0385451 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0383986 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0383005 |
| RPS21 | ribosomal protein S21 | -0.038214 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0381899 |
| HMGA1 | high mobility group AT-hook 1 | -0.0379115 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0374879 |
| RPLP0 | ribosomal protein, large, P0 | -0.0368903 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.036642 |
| H1-0 | H1.0 linker histone | -0.0364955 |
| CUX1 | cut-like homeobox 1 | -0.0364137 |
| MYOF | myoferlin | -0.0363212 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0360149 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0358347 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0352459 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0352405 |
| LDHB | lactate dehydrogenase B | -0.0342274 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0341223 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0340343 |
| DENND1A | DENN/MADD domain containing 1A | -0.0338083 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0334656 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0333178 |
| SETD5 | SET domain containing 5 | -0.0332151 |
| RPS13 | ribosomal protein S13 | -0.0331201 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0330164 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0330006 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0328282 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0325391 |
| ZNRF3 | zinc and ring finger 3 | -0.0324426 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.032326 |
| INSIG2 | insulin induced gene 2 | -0.032307 |
| PARD3 | par-3 family cell polarity regulator | -0.03223 |
| NF1 | neurofibromin 1 | -0.0319653 |
| ASPH | aspartate beta-hydroxylase | -0.031933 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0317841 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0317144 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.031628 |
| RPL11 | ribosomal protein L11 | -0.0316172 |
| ZFHX3 | zinc finger homeobox 3 | -0.0316016 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0309151 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0306295 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0300069 |
