| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.15697 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.153111 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.148109 |
| COL5A1 | collagen, type V, alpha 1 | 0.128507 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.112048 |
| MT2A | metallothionein 2A | 0.11116 |
| ENO1 | enolase 1, (alpha) | 0.0932152 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0911362 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.088175 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0679572 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0613532 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0597361 |
| NAV1 | neuron navigator 1 | 0.0596281 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0595258 |
| NAV2 | neuron navigator 2 | 0.057458 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0568057 |
| LDHA | lactate dehydrogenase A | 0.0530029 |
| SEPTIN9 | septin 9 | 0.0524789 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.051675 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0505361 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0504746 |
| RPS6 | ribosomal protein S6 | 0.0485304 |
| RRM2 | ribonucleotide reductase M2 | 0.0481131 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0468342 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.046314 |
| DTNA | dystrobrevin, alpha | 0.046134 |
| RPL12 | ribosomal protein L12 | 0.0429925 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0421639 |
| CD44 | CD44 molecule (Indian blood group) | 0.0417833 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0413986 |
| LAMB3 | laminin, beta 3 | 0.0411 |
| TNS1 | tensin 1 | 0.0407557 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.039563 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.038392 |
| RPS8 | ribosomal protein S8 | 0.0383871 |
| RPS4X | ribosomal protein S4, X-linked | 0.0382429 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0380174 |
| FAM13A | family with sequence similarity 13, member A | 0.0370133 |
| RUNX1 | runt-related transcription factor 1 | 0.0364353 |
| PODXL | podocalyxin-like | 0.035525 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0347194 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0344406 |
| IGF2 | insulin-like growth factor 2 | 0.0341079 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0335716 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0330157 |
| EMP1 | epithelial membrane protein 1 | 0.0323876 |
| PLEC | plectin | 0.0322333 |
| MKI67 | marker of proliferation Ki-67 | 0.0322246 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0321058 |
| WWOX | WW domain containing oxidoreductase | 0.0320082 |
| FLNB | filamin B, beta | 0.0304241 |
| MT1E | metallothionein 1E | 0.0303417 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0303414 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0301201 |
| RPS12 | ribosomal protein S12 | 0.02961 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0291821 |
| DUSP6 | dual specificity phosphatase 6 | 0.0291814 |
| ANGPTL4 | angiopoietin-like 4 | 0.0288575 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0282279 |
| G0S2 | G0/G1 switch 2 | 0.0273028 |
| RPS3 | ribosomal protein S3 | 0.0269268 |
| RPL23 | ribosomal protein L23 | 0.02676 |
| YBX1 | Y box binding protein 1 | 0.0266506 |
| DIAPH2 | diaphanous-related formin 2 | 0.0265795 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0265029 |
| ANXA2 | annexin A2 | 0.0264081 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0262698 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.026244 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0262201 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0261869 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0257429 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0252112 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.024764 |
| RPLP1 | ribosomal protein, large, P1 | 0.0243572 |
| RASA3 | RAS p21 protein activator 3 | 0.0239265 |
| ASPH | aspartate beta-hydroxylase | 0.0236801 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0236038 |
| FRMD4A | FERM domain containing 4A | 0.0231728 |
| ADM | adrenomedullin | 0.0231097 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0230796 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0230778 |
| HLA-B | major histocompatibility complex, class I, B | 0.0227716 |
| RPL37 | ribosomal protein L37 | 0.0226022 |
| MMP12 | matrix metallopeptidase 12 | 0.0225637 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0223053 |
| RPL37A | ribosomal protein L37a | 0.0222856 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0221434 |
| RACK1 | receptor for activated C kinase 1 | 0.0220094 |
| DEK | DEK proto-oncogene | 0.0219302 |
| RPL26 | ribosomal protein L26 | 0.0218355 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0215272 |
| CENPF | centromere protein F, 350/400kDa | 0.0214038 |
| RPS2 | ribosomal protein S2 | 0.0212124 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0210216 |
| AXL | AXL receptor tyrosine kinase | 0.0208078 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0207614 |
| APP | amyloid beta (A4) precursor protein | 0.0207151 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0205826 |
| SET | SET nuclear proto-oncogene | 0.020569 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.020329 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.154929 |
| HMGA2 | high mobility group AT-hook 2 | -0.121271 |
| FN1 | fibronectin 1 | -0.106818 |
| TMSB10 | thymosin beta 10 | -0.0971686 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0949636 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0944537 |
| VCL | vinculin | -0.0793138 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0768953 |
| RTN4 | reticulon 4 | -0.0716978 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.069828 |
| TENM2 | teneurin transmembrane protein 2 | -0.0668203 |
| CDH13 | cadherin 13 | -0.0577491 |
| ACTG1 | actin gamma 1 | -0.0494481 |
| GLIS3 | GLIS family zinc finger 3 | -0.0491154 |
| SETD5 | SET domain containing 5 | -0.0486171 |
| VIM | vimentin | -0.0463637 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0451802 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0431174 |
| EGR1 | early growth response 1 | -0.0421141 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0417741 |
| COL1A1 | collagen, type I, alpha 1 | -0.038577 |
| LOX | lysyl oxidase | -0.0382637 |
| SBF2 | SET binding factor 2 | -0.0354884 |
| ANKRD28 | ankyrin repeat domain 28 | -0.03514 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0343048 |
| OSMR | oncostatin M receptor | -0.0332167 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0331294 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0321476 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0319295 |
| CD109 | CD109 molecule | -0.0306969 |
| PTMA | prothymosin, alpha | -0.0306024 |
| PDE10A | phosphodiesterase 10A | -0.030091 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0298736 |
| INHBA | inhibin, beta A | -0.0298456 |
| PDLIM5 | PDZ and LIM domain 5 | -0.028982 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.028844 |
| PCNX4 | pecanex 4 | -0.0281948 |
| TUBB6 | tubulin, beta 6 class V | -0.0281464 |
| CLMP | CXADR-like membrane protein | -0.0281451 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0277787 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.027745 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0269484 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.026679 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.026648 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0261638 |
| VMP1 | vacuole membrane protein 1 | -0.0258866 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0256197 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0254688 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0251486 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0247635 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0246075 |
| TMEM263 | transmembrane protein 263 | -0.0242383 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0236736 |
| TNNC1 | troponin C type 1 (slow) | -0.0236458 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0234483 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0231327 |
| CUX1 | cut-like homeobox 1 | -0.0227455 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0219778 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0217143 |
| MSN | moesin | -0.021662 |
| VASP | vasodilator-stimulated phosphoprotein | -0.0216564 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.0213714 |
| WASF2 | WAS protein family, member 2 | -0.0212585 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0211234 |
| RASA2 | RAS p21 protein activator 2 | -0.0209156 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0208172 |
| TAGLN2 | transgelin 2 | -0.0207808 |
| RRBP1 | ribosome binding protein 1 | -0.0207454 |
| FSTL1 | follistatin-like 1 | -0.0205789 |
| HDLBP | high density lipoprotein binding protein | -0.0204273 |
| ARF4 | ADP-ribosylation factor 4 | -0.0203181 |
| GLG1 | golgi glycoprotein 1 | -0.0201479 |
| ACTN4 | actinin, alpha 4 | -0.020078 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase | -0.0200425 |
| TAOK1 | TAO kinase 1 | -0.0200073 |
| PCNX1 | pecanex 1 | -0.0198791 |
| FAM193A | family with sequence similarity 193, member A | -0.0198334 |
| ZNF207 | zinc finger protein 207 | -0.0197953 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0194685 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0193514 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0193427 |
| EXOC6B | exocyst complex component 6B | -0.019148 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0190513 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0189787 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0189701 |
| SPAG9 | sperm associated antigen 9 | -0.0189541 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0189178 |
| ZNF609 | zinc finger protein 609 | -0.0188928 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0188832 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0187187 |
| NUMB | numb homolog (Drosophila) | -0.0187166 |
| RAI14 | retinoic acid induced 14 | -0.0185738 |
| TXNIP | thioredoxin interacting protein | -0.0185029 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0184913 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0183753 |
| ETNK1 | ethanolamine kinase 1 | -0.0183669 |
| NF1 | neurofibromin 1 | -0.0183173 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0182375 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0180782 |
| NABP1 | nucleic acid binding protein 1 | -0.0180746 |
