| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.0738302 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0433306 |
| HMGA2 | high mobility group AT-hook 2 | 0.0431068 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0425437 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0392273 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0334122 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0317446 |
| NAV2 | neuron navigator 2 | 0.0311163 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0294676 |
| ASPH | aspartate beta-hydroxylase | 0.0278506 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0272192 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.026396 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0256718 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0246784 |
| CDH13 | cadherin 13 | 0.0242761 |
| GLIS3 | GLIS family zinc finger 3 | 0.0241422 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0236778 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.023418 |
| HDAC9 | histone deacetylase 9 | 0.0232341 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0228394 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0226559 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0219094 |
| NAV1 | neuron navigator 1 | 0.0215676 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0211311 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0206063 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0204698 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0191332 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0191099 |
| APP | amyloid beta (A4) precursor protein | 0.0190669 |
| VCL | vinculin | 0.018918 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0187227 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.018484 |
| PLEC | plectin | 0.0183019 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0181537 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0179616 |
| MYO10 | myosin X | 0.0173437 |
| ACTN1 | actinin, alpha 1 | 0.0171217 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0170833 |
| VMP1 | vacuole membrane protein 1 | 0.0169201 |
| SMYD3 | SET and MYND domain containing 3 | 0.0161644 |
| EFNA5 | ephrin-A5 | 0.0160259 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0158105 |
| JAG1 | jagged 1 | 0.0154747 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0154723 |
| NOTCH2 | notch 2 | 0.0154309 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.015001 |
| FLNB | filamin B, beta | 0.0146331 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0145122 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0137678 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0137102 |
| RUNX1 | runt-related transcription factor 1 | 0.0136417 |
| RSU1 | Ras suppressor protein 1 | 0.0135326 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.013505 |
| SVIL | supervillin | 0.0134566 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0130621 |
| DST | dystonin | 0.0126075 |
| RASAL2 | RAS protein activator like 2 | 0.0125571 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0125042 |
| CDK14 | cyclin-dependent kinase 14 | 0.0123867 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0122052 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.012205 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0118586 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0117473 |
| FAM107B | family with sequence similarity 107, member B | 0.011738 |
| HAS2 | hyaluronan synthase 2 | 0.0116473 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0116119 |
| EXOC6B | exocyst complex component 6B | 0.0114746 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0114483 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0113658 |
| NABP1 | nucleic acid binding protein 1 | 0.0113037 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0112373 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0112345 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0112337 |
| ZNF644 | zinc finger protein 644 | 0.0112326 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0111601 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0110709 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0110514 |
| VEGFC | vascular endothelial growth factor C | 0.0108912 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0108367 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0108273 |
| ATXN1 | ataxin 1 | 0.0107867 |
| TCF20 | transcription factor 20 (AR1) | 0.0107676 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0107523 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0107265 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0107109 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0106214 |
| FLNA | filamin A, alpha | 0.010607 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0105438 |
| SKI | SKI proto-oncogene | 0.0105194 |
| KLF12 | Kruppel-like factor 12 | 0.0105048 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0105036 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0103724 |
| CNTN5 | contactin 5 | 0.0103548 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0103372 |
| USP34 | ubiquitin specific peptidase 34 | 0.01029 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0102299 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.010098 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.010096 |
| NRP1 | neuropilin 1 | 0.0100483 |
| EHBP1 | EH domain binding protein 1 | 0.0100274 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.197772 |
| NDRG1 | N-myc downstream regulated 1 | -0.187349 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.185676 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.178248 |
| FN1 | fibronectin 1 | -0.163979 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.159897 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.143598 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.143063 |
| COL1A1 | collagen, type I, alpha 1 | -0.138761 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.126967 |
| COL1A2 | collagen, type I, alpha 2 | -0.123061 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.107132 |
| CADM1 | cell adhesion molecule 1 | -0.0783304 |
| IER3 | immediate early response 3 | -0.0751895 |
| TPM4 | tropomyosin 4 | -0.0751556 |
| TMSB10 | thymosin beta 10 | -0.0702188 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0693986 |
| PTMA | prothymosin, alpha | -0.0667529 |
| FTL | ferritin, light polypeptide | -0.0628006 |
| LOX | lysyl oxidase | -0.0597334 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0561385 |
| CANX | calnexin | -0.0560469 |
| ENO1 | enolase 1, (alpha) | -0.0555786 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0518707 |
| MT2A | metallothionein 2A | -0.0515546 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0495 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0490351 |
| UBC | ubiquitin C | -0.0473443 |
| ADM | adrenomedullin | -0.0468283 |
| RPS6 | ribosomal protein S6 | -0.0467204 |
| RPL35A | ribosomal protein L35a | -0.0448297 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.044171 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0433507 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0429193 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0429135 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0424473 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0421417 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0414342 |
| MTDH | metadherin | -0.0408428 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0406228 |
| PGK1 | phosphoglycerate kinase 1 | -0.0401535 |
| LOXL2 | lysyl oxidase-like 2 | -0.040093 |
| LDHA | lactate dehydrogenase A | -0.0399163 |
| CALR | calreticulin | -0.0398381 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0380921 |
| B2M | beta-2-microglobulin | -0.0379395 |
| GOLGA4 | golgin A4 | -0.0374656 |
| CAVIN1 | caveolae associated protein 1 | -0.0374294 |
| RPS8 | ribosomal protein S8 | -0.0371348 |
| CD44 | CD44 molecule (Indian blood group) | -0.0359107 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0346616 |
| ACTG1 | actin gamma 1 | -0.0341615 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0339457 |
| PDE10A | phosphodiesterase 10A | -0.0330252 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0322254 |
| HLA-B | major histocompatibility complex, class I, B | -0.0316029 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0314788 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0312762 |
| S100A6 | S100 calcium binding protein A6 | -0.0312191 |
| ZNF292 | zinc finger protein 292 | -0.0305367 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0293213 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0292275 |
| PKM | pyruvate kinase, muscle | -0.0291346 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0290811 |
| FBN1 | fibrillin 1 | -0.0289611 |
| S100A9 | S100 calcium binding protein A9 | -0.0284696 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0280732 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0280358 |
| FAM162A | family with sequence similarity 162, member A | -0.0279993 |
| TRAM1 | translocation associated membrane protein 1 | -0.0279659 |
| BBX | bobby sox homolog (Drosophila) | -0.0277387 |
| GNAS | GNAS complex locus | -0.0275394 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0275273 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0269201 |
| HLA-A | major histocompatibility complex, class I, A | -0.0266535 |
| RLF | rearranged L-myc fusion | -0.0262246 |
| TMSB4X | thymosin beta 4, X-linked | -0.0260505 |
| CD109 | CD109 molecule | -0.0258559 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0257381 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0254873 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0254637 |
| SETD5 | SET domain containing 5 | -0.0253498 |
| QKI | QKI, KH domain containing, RNA binding | -0.0252333 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0250164 |
| CA12 | carbonic anhydrase XII | -0.024777 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0246661 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0241794 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0233977 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0231834 |
| VEGFA | vascular endothelial growth factor A | -0.0230766 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0228632 |
| DSTN | destrin (actin depolymerizing factor) | -0.0228231 |
| RRBP1 | ribosome binding protein 1 | -0.0227726 |
| RTN4 | reticulon 4 | -0.0224658 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0224326 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0224227 |
| SEPTIN7 | septin 7 | -0.0223156 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0222411 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0222223 |
| ANXA2 | annexin A2 | -0.0220349 |
