| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.296218 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.167112 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.125922 |
| SVIL | supervillin | 0.123985 |
| DSPP | dentin sialophosphoprotein | 0.116209 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.104406 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0799069 |
| MT2A | metallothionein 2A | 0.0717279 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0699754 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0697563 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0683561 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0661441 |
| APOB | apolipoprotein B | 0.0636828 |
| BCL2L1 | BCL2-like 1 | 0.0615064 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.061461 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0569873 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0569249 |
| FAM107B | family with sequence similarity 107, member B | 0.0560928 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0550267 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0519476 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0468847 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0466978 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0456761 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0454004 |
| INTS6 | integrator complex subunit 6 | 0.0445585 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0441104 |
| EFNA1 | ephrin-A1 | 0.04383 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0434499 |
| NDRG1 | N-myc downstream regulated 1 | 0.0411237 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0397359 |
| RPS4X | ribosomal protein S4, X-linked | 0.0396548 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0391369 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0385375 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0383374 |
| RPL23 | ribosomal protein L23 | 0.0383358 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0376537 |
| LDHA | lactate dehydrogenase A | 0.0368012 |
| TNS1 | tensin 1 | 0.0352499 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0348653 |
| CLIC4 | chloride intracellular channel 4 | 0.0347903 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0345954 |
| SEPTIN9 | septin 9 | 0.0342834 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0332585 |
| KLF6 | Kruppel-like factor 6 | 0.0328242 |
| FUS | FUS RNA binding protein | 0.0326896 |
| RAD51B | RAD51 paralog B | 0.0325148 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0322724 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0322367 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0321036 |
| TF | transferrin | 0.0298439 |
| CREBBP | CREB binding protein | 0.0290615 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.028858 |
| PRELID2 | PRELI domain containing 2 | 0.0288206 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0288076 |
| A2M | alpha-2-macroglobulin | 0.0286748 |
| TLE4 | transducin-like enhancer of split 4 | 0.0282113 |
| ATXN1 | ataxin 1 | 0.0282004 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0281096 |
| MYO1E | myosin IE | 0.0279021 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.027779 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0268005 |
| FLNB | filamin B, beta | 0.0267917 |
| KIF21A | kinesin family member 21A | 0.0264761 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0262836 |
| FOXP1 | forkhead box P1 | 0.0262768 |
| KRT18 | keratin 18, type I | 0.0260942 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0260652 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0260403 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0258343 |
| FERMT2 | fermitin family member 2 | 0.0252101 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0247642 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0246493 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0245818 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0245672 |
| FLNA | filamin A, alpha | 0.0245454 |
| JAG1 | jagged 1 | 0.0244659 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0244137 |
| RPS12 | ribosomal protein S12 | 0.0243974 |
| CLTC | clathrin, heavy chain (Hc) | 0.0243598 |
| ACTN1 | actinin, alpha 1 | 0.0241903 |
| USP34 | ubiquitin specific peptidase 34 | 0.0241772 |
| PLEC | plectin | 0.0239551 |
| CRY1 | cryptochrome circadian clock 1 | 0.0239116 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0237738 |
| RASA2 | RAS p21 protein activator 2 | 0.0235535 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0234742 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0233854 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.0233715 |
| BPTF | bromodomain PHD finger transcription factor | 0.0232243 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0231673 |
| RPL11 | ribosomal protein L11 | 0.0231626 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0231 |
| JAK1 | Janus kinase 1 | 0.0230959 |
| FN1 | fibronectin 1 | 0.0229813 |
| EZR | ezrin | 0.0228942 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.0228262 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0226506 |
| SFTPA2 | surfactant protein A2 | 0.0225185 |
| AFDN | afadin, adherens junction formation factor | 0.0223901 |
| TCIM | transcriptional and immune response regulator | 0.0222069 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.261409 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.170727 |
| C3 | complement component 3 | -0.169178 |
| FNDC3B | fibronectin type III domain containing 3B | -0.148402 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.142732 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.100071 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0974646 |
| CP | ceruloplasmin (ferroxidase) | -0.0879627 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0757135 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0734709 |
| SLC38A2 | solute carrier family 38, member 2 | -0.072859 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0701978 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.068023 |
| PLIN2 | perilipin 2 | -0.0651125 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.064735 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0613294 |
| APOA2 | apolipoprotein A-II | -0.0564713 |
| TPM4 | tropomyosin 4 | -0.0539455 |
| ASPH | aspartate beta-hydroxylase | -0.0537739 |
| EGR1 | early growth response 1 | -0.0515483 |
| GPC6 | glypican 6 | -0.0507101 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0506338 |
| VCL | vinculin | -0.0470087 |
| MSI2 | musashi RNA-binding protein 2 | -0.0433905 |
| OSMR | oncostatin M receptor | -0.0432685 |
| HMGA1 | high mobility group AT-hook 1 | -0.0429917 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0425317 |
| LYZ | lysozyme | -0.0423605 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0415127 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0411203 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0407662 |
| PERP | PERP, TP53 apoptosis effector | -0.0406163 |
| GDF15 | growth differentiation factor 15 | -0.0395696 |
| RPS6 | ribosomal protein S6 | -0.039213 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0383724 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0374673 |
| FERMT1 | fermitin family member 1 | -0.037147 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0366567 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0365734 |
| RPL35A | ribosomal protein L35a | -0.0358112 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0357982 |
| RPLP1 | ribosomal protein, large, P1 | -0.0353504 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0353017 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0352829 |
| PEG3 | paternally expressed 3 | -0.0343407 |
| EHBP1 | EH domain binding protein 1 | -0.0332824 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0332635 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0324744 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0319522 |
| ITGAV | integrin, alpha V | -0.0316433 |
| ATP10A | ATPase, class V, type 10A | -0.0312053 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0309505 |
| NPR2 | natriuretic peptide receptor 2 | -0.0304066 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0301219 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0299408 |
| GNAS | GNAS complex locus | -0.0297234 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0296875 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0291762 |
| RIGI | RNA sensor RIG-I | -0.0289232 |
| RPLP0 | ribosomal protein, large, P0 | -0.0288248 |
| ZNF644 | zinc finger protein 644 | -0.0286906 |
| MX2 | MX dynamin-like GTPase 2 | -0.028127 |
| TMEM51 | transmembrane protein 51 | -0.0278842 |
| PGK1 | phosphoglycerate kinase 1 | -0.0271773 |
| RBM39 | RNA binding motif protein 39 | -0.0270919 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0268512 |
| RBM25 | RNA binding motif protein 25 | -0.0266174 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0264941 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0262832 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0261494 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0259045 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0257555 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0256007 |
| ZFHX3 | zinc finger homeobox 3 | -0.0253907 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0253805 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0253774 |
| TMEM123 | transmembrane protein 123 | -0.0251143 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0247009 |
| WWC1 | WW and C2 domain containing 1 | -0.0246763 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.024502 |
| MRTFA | myocardin related transcription factor A | -0.0242943 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0242933 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.02401 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | -0.0240063 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0238266 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0238086 |
| CALD1 | caldesmon 1 | -0.023637 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0235001 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0234384 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0234106 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0232833 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0232562 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0231852 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0231469 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0230886 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.0229534 |
| RRBP1 | ribosome binding protein 1 | -0.0228735 |
| PLSCR1 | phospholipid scramblase 1 | -0.0227929 |
| ARFGEF3 | ARFGEF family member 3 | -0.0226426 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0225473 |
