| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.18324 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.143205 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.102874 |
| PODXL | podocalyxin-like | 0.0933519 |
| NAV2 | neuron navigator 2 | 0.077112 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0751905 |
| ERBIN | erbb2 interacting protein | 0.0570183 |
| ACTN1 | actinin, alpha 1 | 0.0530538 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0459724 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0458775 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0445129 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0420398 |
| FLNB | filamin B, beta | 0.0403544 |
| BCL2L1 | BCL2-like 1 | 0.0362485 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0355673 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0353837 |
| CD44 | CD44 molecule (Indian blood group) | 0.0327902 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0327596 |
| SET | SET nuclear proto-oncogene | 0.0314108 |
| SEPTIN9 | septin 9 | 0.031288 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0308301 |
| FLNA | filamin A, alpha | 0.0303245 |
| INTS6 | integrator complex subunit 6 | 0.0299715 |
| RPS6 | ribosomal protein S6 | 0.0291197 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0288422 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0285289 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.02829 |
| TLE4 | transducin-like enhancer of split 4 | 0.0282509 |
| RUNX1 | runt-related transcription factor 1 | 0.02748 |
| RPS3 | ribosomal protein S3 | 0.027147 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0270016 |
| RPS8 | ribosomal protein S8 | 0.0265759 |
| LDHA | lactate dehydrogenase A | 0.0262662 |
| MSN | moesin | 0.0258337 |
| YBX1 | Y box binding protein 1 | 0.0257915 |
| WWOX | WW domain containing oxidoreductase | 0.0252961 |
| RPS12 | ribosomal protein S12 | 0.0244184 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0243014 |
| CLIC4 | chloride intracellular channel 4 | 0.0242638 |
| MCL1 | myeloid cell leukemia 1 | 0.024071 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0236431 |
| ASPH | aspartate beta-hydroxylase | 0.0235829 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0233238 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0227857 |
| ATXN1 | ataxin 1 | 0.0225808 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0224822 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0221119 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0218341 |
| RPL23 | ribosomal protein L23 | 0.0215918 |
| PRELID2 | PRELI domain containing 2 | 0.0214117 |
| SMYD3 | SET and MYND domain containing 3 | 0.0213762 |
| MYO10 | myosin X | 0.0213381 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0212527 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0211291 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0209398 |
| RPS4X | ribosomal protein S4, X-linked | 0.0208234 |
| CALD1 | caldesmon 1 | 0.0206756 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0206723 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0206541 |
| RPL5 | ribosomal protein L5 | 0.0204973 |
| SMC4 | structural maintenance of chromosomes 4 | 0.020243 |
| CREBBP | CREB binding protein | 0.0199256 |
| ANGPTL4 | angiopoietin-like 4 | 0.0198769 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0193949 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0193765 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.01936 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0193011 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0192992 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0192486 |
| RPS17 | ribosomal protein S17 | 0.0192415 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0191788 |
| FHIT | fragile histidine triad | 0.0191425 |
| APP | amyloid beta (A4) precursor protein | 0.0190868 |
| NDRG1 | N-myc downstream regulated 1 | 0.0190367 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.019024 |
| EGFR | epidermal growth factor receptor | 0.0189016 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.018793 |
| RPS2 | ribosomal protein S2 | 0.0184049 |
| RACK1 | receptor for activated C kinase 1 | 0.0183724 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0182921 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0181423 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0179789 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0177193 |
| FUS | FUS RNA binding protein | 0.0177126 |
| TPM3 | tropomyosin 3 | 0.0175476 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.017464 |
| RPL37A | ribosomal protein L37a | 0.0171615 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0170338 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0168227 |
| TUFT1 | tuftelin 1 | 0.0164791 |
| EFNA5 | ephrin-A5 | 0.0164765 |
| HMGA1 | high mobility group AT-hook 1 | 0.01647 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0164653 |
| NAV1 | neuron navigator 1 | 0.0163085 |
| PLSCR1 | phospholipid scramblase 1 | 0.0162549 |
| RAD51B | RAD51 paralog B | 0.0161977 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0160309 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0159139 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0157111 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0156571 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.263509 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.215509 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.186599 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.142514 |
| GLIS3 | GLIS family zinc finger 3 | -0.120071 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.115314 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0957463 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0926967 |
| HLA-B | major histocompatibility complex, class I, B | -0.0898383 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.075316 |
| POSTN | periostin, osteoblast specific factor | -0.0721449 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0704657 |
| ATP13A3 | ATPase type 13A3 | -0.0691762 |
| PLCB4 | phospholipase C, beta 4 | -0.0681529 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0665705 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.066235 |
| PGK1 | phosphoglycerate kinase 1 | -0.0648707 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0603051 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0602495 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0581551 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.05763 |
| RAI14 | retinoic acid induced 14 | -0.0574371 |
| TMSB4X | thymosin beta 4, X-linked | -0.0573831 |
| SULF1 | sulfatase 1 | -0.0558166 |
| CANX | calnexin | -0.0531062 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0520522 |
| LOX | lysyl oxidase | -0.0507002 |
| FSTL1 | follistatin-like 1 | -0.0493856 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0485049 |
| GOLGA4 | golgin A4 | -0.0471155 |
| AHNAK | AHNAK nucleoprotein | -0.0467052 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0455485 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0442066 |
| TMEM178B | transmembrane protein 178B | -0.0440536 |
| CTSD | cathepsin D | -0.0436832 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0436077 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0433115 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0432855 |
| PLIN2 | perilipin 2 | -0.0428323 |
| COL5A2 | collagen, type V, alpha 2 | -0.042251 |
| TGFB2 | transforming growth factor, beta 2 | -0.0416641 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0416428 |
| MMP12 | matrix metallopeptidase 12 | -0.0415266 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0396787 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0394851 |
| ARF4 | ADP-ribosylation factor 4 | -0.0394235 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.039276 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.039248 |
| LMAN1 | lectin, mannose-binding, 1 | -0.038478 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0382876 |
| OSMR | oncostatin M receptor | -0.0371063 |
| ZNF804A | zinc finger protein 804A | -0.035868 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.035164 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0344394 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0344041 |
| HLA-E | major histocompatibility complex, class I, E | -0.0332714 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0332173 |
| MAP1B | microtubule-associated protein 1B | -0.032556 |
| BMPER | BMP binding endothelial regulator | -0.0308492 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0307642 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0306664 |
| CUL4B | cullin 4B | -0.0302677 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0301018 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0298652 |
| S100A6 | S100 calcium binding protein A6 | -0.0296838 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0295594 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0292844 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0288809 |
| CAVIN1 | caveolae associated protein 1 | -0.0282413 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0278251 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0276666 |
| DIAPH3 | diaphanous-related formin 3 | -0.0275708 |
| COPA | coatomer protein complex, subunit alpha | -0.0273875 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0272773 |
| MT1X | metallothionein 1X | -0.0271946 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0268568 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0267974 |
| PRRC2B | proline-rich coiled-coil 2B | -0.026721 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0264461 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | -0.0264224 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0262766 |
| FTL | ferritin, light polypeptide | -0.02608 |
| DEK | DEK proto-oncogene | -0.0260745 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0260736 |
| TMEM263 | transmembrane protein 263 | -0.025708 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0254035 |
| NRG1 | neuregulin 1 | -0.0253971 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0252337 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0250926 |
| CALR | calreticulin | -0.0249518 |
| PTX3 | pentraxin 3, long | -0.0247244 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0244664 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.023825 |
| TXNRD1 | thioredoxin reductase 1 | -0.0237256 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0235589 |
| ANXA2 | annexin A2 | -0.023251 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.023236 |
| TRAM1 | translocation associated membrane protein 1 | -0.0228977 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0228877 |
| PRKD1 | protein kinase D1 | -0.0226416 |
