| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.135533 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.105321 |
| RPS3 | ribosomal protein S3 | 0.103444 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.101139 |
| RPS12 | ribosomal protein S12 | 0.0977021 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0937837 |
| RPL23 | ribosomal protein L23 | 0.0763126 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0750373 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0716959 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0714142 |
| RPS4X | ribosomal protein S4, X-linked | 0.061876 |
| RPL37A | ribosomal protein L37a | 0.0590714 |
| INTS6 | integrator complex subunit 6 | 0.058581 |
| RPS17 | ribosomal protein S17 | 0.0552903 |
| HMGA2 | high mobility group AT-hook 2 | 0.0549944 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0545183 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0542916 |
| ASPH | aspartate beta-hydroxylase | 0.0493109 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0464232 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0464071 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.044833 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0409498 |
| NABP1 | nucleic acid binding protein 1 | 0.0408628 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0407467 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0405169 |
| NTM | neurotrimin | 0.0398 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0388776 |
| MYO10 | myosin X | 0.0381306 |
| RPL26 | ribosomal protein L26 | 0.0381154 |
| FLNB | filamin B, beta | 0.0381087 |
| RPS8 | ribosomal protein S8 | 0.0375573 |
| RPS2 | ribosomal protein S2 | 0.0368247 |
| AEBP2 | AE binding protein 2 | 0.035564 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0355087 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0348614 |
| RACK1 | receptor for activated C kinase 1 | 0.0347103 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0346547 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0343783 |
| RPL12 | ribosomal protein L12 | 0.0343543 |
| NAV3 | neuron navigator 3 | 0.0341925 |
| ACTN1 | actinin, alpha 1 | 0.0338435 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0337282 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0333559 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0331121 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0330794 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0329049 |
| RPL9 | ribosomal protein L9 | 0.032586 |
| MT2A | metallothionein 2A | 0.0324297 |
| KISS1 | KiSS-1 metastasis-suppressor | 0.0322469 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0315582 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0312685 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0309783 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0306937 |
| CD44 | CD44 molecule (Indian blood group) | 0.0298458 |
| TXNIP | thioredoxin interacting protein | 0.0297744 |
| BPTF | bromodomain PHD finger transcription factor | 0.0290665 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0284812 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0271172 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0270308 |
| KIAA1549L | KIAA1549-like | 0.0269459 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0269242 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0264953 |
| FLNA | filamin A, alpha | 0.0264823 |
| SATB2 | SATB homeobox 2 | 0.0259291 |
| RPL31 | ribosomal protein L31 | 0.0252134 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0250809 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0249085 |
| HDAC9 | histone deacetylase 9 | 0.0248616 |
| MCL1 | myeloid cell leukemia 1 | 0.0247523 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0247305 |
| USP34 | ubiquitin specific peptidase 34 | 0.0247047 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0245932 |
| RPL36 | ribosomal protein L36 | 0.0242632 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0239222 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0237131 |
| EFNB2 | ephrin-B2 | 0.0236251 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0235218 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0233908 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0231199 |
| RPL18 | ribosomal protein L18 | 0.0230279 |
| RPS11 | ribosomal protein S11 | 0.0229994 |
| RPS29 | ribosomal protein S29 | 0.0228906 |
| STK4 | serine/threonine kinase 4 | 0.022842 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0222134 |
| NLK | nemo-like kinase | 0.0220017 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0219307 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0218687 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0217907 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0215435 |
| COMMD10 | COMM domain containing 10 | 0.0211907 |
| ITGA6 | integrin, alpha 6 | 0.021039 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0208228 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0206822 |
| APP | amyloid beta (A4) precursor protein | 0.0205745 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0203807 |
| RPL27 | ribosomal protein L27 | 0.02028 |
| GPHN | gephyrin | 0.0202175 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0202103 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0201323 |
| RB1 | retinoblastoma 1 | 0.0198358 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | -0.190839 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.190385 |
| MMP12 | matrix metallopeptidase 12 | -0.175997 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.143409 |
| VIM | vimentin | -0.141507 |
| LSAMP | limbic system-associated membrane protein | -0.101935 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0846515 |
| CD109 | CD109 molecule | -0.0825162 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0821657 |
| GPC6 | glypican 6 | -0.0789748 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0780284 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0757396 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.07573 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0720418 |
| ANXA2 | annexin A2 | -0.070052 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0674895 |
| FTL | ferritin, light polypeptide | -0.0599872 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0581657 |
| WDR45B | WD repeat domain 45B | -0.0565361 |
| PTMA | prothymosin, alpha | -0.0558698 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.055237 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0543312 |
| POTEF | POTE ankyrin domain family, member F | -0.0537729 |
| CDH13 | cadherin 13 | -0.05187 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0508693 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0502362 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0500946 |
| PKM | pyruvate kinase, muscle | -0.0480777 |
| TPM4 | tropomyosin 4 | -0.0479861 |
| RPS6 | ribosomal protein S6 | -0.0469398 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0467355 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0457474 |
| GOLGA4 | golgin A4 | -0.0455208 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0449806 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0444817 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0443382 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0431111 |
| PGK1 | phosphoglycerate kinase 1 | -0.0431046 |
| ACTG1 | actin gamma 1 | -0.0423964 |
| EFNA5 | ephrin-A5 | -0.041365 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0413062 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.041005 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0409934 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0405377 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0400343 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0386369 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0379327 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0370964 |
| FOSL1 | FOS-like antigen 1 | -0.0370452 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0359756 |
| RPL35A | ribosomal protein L35a | -0.0358409 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0349664 |
| RTN4 | reticulon 4 | -0.0346779 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0341892 |
| FN1 | fibronectin 1 | -0.0339741 |
| CTSB | cathepsin B | -0.0333861 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0330544 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0330509 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0330009 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0329449 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0328794 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0328489 |
| ZNF292 | zinc finger protein 292 | -0.0325121 |
| SMAP1 | small ArfGAP 1 | -0.0324139 |
| SEPTIN7 | septin 7 | -0.03241 |
| GNAS | GNAS complex locus | -0.0317263 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0314631 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0313534 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0313139 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0309976 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0308686 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0305201 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0304379 |
| RPL13A | ribosomal protein L13a | -0.0302288 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0298623 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0298061 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0290815 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0290621 |
| TMEM263 | transmembrane protein 263 | -0.0287595 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0281831 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0281818 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.028148 |
| CAVIN1 | caveolae associated protein 1 | -0.0278697 |
| CANX | calnexin | -0.0277809 |
| RPS20 | ribosomal protein S20 | -0.0276193 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0274722 |
| RPLP0 | ribosomal protein, large, P0 | -0.0272284 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0265496 |
| NUP58 | nucleoporin 58 | -0.026527 |
| SETD5 | SET domain containing 5 | -0.02641 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0263273 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0262934 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.026135 |
| INSIG2 | insulin induced gene 2 | -0.0260909 |
| RNF145 | ring finger protein 145 | -0.0257681 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0256871 |
| USP3 | ubiquitin specific peptidase 3 | -0.0255735 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0254611 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.025315 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.025104 |
