| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.235821 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.179023 |
| LMO7 | LIM domain 7 | 0.161245 |
| LDHA | lactate dehydrogenase A | 0.102602 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.102401 |
| KRT18 | keratin 18, type I | 0.0817393 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0704146 |
| MYO1E | myosin IE | 0.0694831 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.069318 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0604194 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0552132 |
| MED13 | mediator complex subunit 13 | 0.0550138 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0549133 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0533392 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0508003 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0467615 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.046443 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.046092 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0449281 |
| FAT1 | FAT atypical cadherin 1 | 0.0436343 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0415656 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0413649 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0401141 |
| AREG | amphiregulin | 0.0384631 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0382165 |
| TXNIP | thioredoxin interacting protein | 0.0377254 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0374687 |
| PDZD8 | PDZ domain containing 8 | 0.0361164 |
| EHF | ets homologous factor | 0.0360444 |
| CD44 | CD44 molecule (Indian blood group) | 0.0355788 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0345908 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0342035 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0336288 |
| MUC13 | mucin 13, cell surface associated | 0.0334218 |
| GDA | guanine deaminase | 0.0328937 |
| ITGA6 | integrin, alpha 6 | 0.0321072 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0319146 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0318667 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0313207 |
| RPS4X | ribosomal protein S4, X-linked | 0.0312725 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0308823 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0307314 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0302228 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0301431 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.029759 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0295109 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0294097 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0291848 |
| EREG | epiregulin | 0.0284656 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0282998 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0276311 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0275631 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0275373 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0255683 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0254612 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0253096 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0234268 |
| USP53 | ubiquitin specific peptidase 53 | 0.0234038 |
| ASPH | aspartate beta-hydroxylase | 0.0232586 |
| PDE10A | phosphodiesterase 10A | 0.0229686 |
| TRIM2 | tripartite motif containing 2 | 0.0229615 |
| PRELID2 | PRELI domain containing 2 | 0.022844 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0225699 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0225012 |
| PLS1 | plastin 1 | 0.0224192 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0224117 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0223743 |
| LAMA4 | laminin, alpha 4 | 0.0222041 |
| EPCAM | epithelial cell adhesion molecule | 0.0220876 |
| FOXO1 | forkhead box O1 | 0.0220771 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0220758 |
| KIAA1328 | KIAA1328 | 0.0219269 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0217911 |
| APP | amyloid beta (A4) precursor protein | 0.0216457 |
| PKP2 | plakophilin 2 | 0.0215145 |
| SQSTM1 | sequestosome 1 | 0.0214169 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0213238 |
| RPLP0 | ribosomal protein, large, P0 | 0.0212575 |
| DUSP4 | dual specificity phosphatase 4 | 0.0212347 |
| FBXO11 | F-box protein 11 | 0.0212307 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0208836 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0208174 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0207235 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0206859 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0204909 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0203821 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0202846 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0202393 |
| ENO1 | enolase 1, (alpha) | 0.0202133 |
| EXPH5 | exophilin 5 | 0.0201881 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0201546 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0196362 |
| SMAD2 | SMAD family member 2 | 0.0194972 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0194292 |
| RNF43 | ring finger protein 43 | 0.0191154 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0190326 |
| SERINC5 | serine incorporator 5 | 0.0189798 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0189136 |
| DIAPH3 | diaphanous-related formin 3 | 0.0187302 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0185228 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.230191 |
| PTMA | prothymosin, alpha | -0.110501 |
| RPS6 | ribosomal protein S6 | -0.104113 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0988855 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0966161 |
| TMSB10 | thymosin beta 10 | -0.084677 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0661451 |
| FLNB | filamin B, beta | -0.0619828 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.059781 |
| PIGR | polymeric immunoglobulin receptor | -0.0596446 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0550464 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0546283 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0546201 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0543716 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0535743 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0528424 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0519905 |
| EZR | ezrin | -0.0514494 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0480335 |
| ACTN4 | actinin, alpha 4 | -0.0472206 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0470961 |
| PARD3 | par-3 family cell polarity regulator | -0.045429 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0443574 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0440511 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0437846 |
| CCNY | cyclin Y | -0.0437124 |
| NFIA | nuclear factor I/A | -0.0436658 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0436553 |
| GOLGA4 | golgin A4 | -0.0430963 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0422769 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0421931 |
| ZNF292 | zinc finger protein 292 | -0.0415529 |
| AHNAK | AHNAK nucleoprotein | -0.0407754 |
| CALB1 | calbindin 1, 28kDa | -0.0407122 |
| RNF217 | ring finger protein 217 | -0.0406176 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.040426 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.039358 |
| ONECUT3 | one cut homeobox 3 | -0.0381504 |
| GLG1 | golgi glycoprotein 1 | -0.0380853 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0378442 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0378199 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0376686 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0376143 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0375017 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0373359 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0359995 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0357772 |
| GPHN | gephyrin | -0.0354174 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0354174 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.034933 |
| RAD51B | RAD51 paralog B | -0.0345399 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0342126 |
| MECOM | MDS1 and EVI1 complex locus | -0.0336549 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0335304 |
| RIN2 | Ras and Rab interactor 2 | -0.0334009 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0330557 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0328271 |
| PTK2 | protein tyrosine kinase 2 | -0.0326064 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0323571 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.031806 |
| VEGFA | vascular endothelial growth factor A | -0.0317628 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0316245 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0315069 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0313182 |
| MSI2 | musashi RNA-binding protein 2 | -0.0311142 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0309893 |
| RPS12 | ribosomal protein S12 | -0.0307284 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0304681 |
| DENND1A | DENN/MADD domain containing 1A | -0.0302336 |
| NDRG1 | N-myc downstream regulated 1 | -0.0301676 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0298272 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0296103 |
| SLC10A7 | solute carrier family 10, member 7 | -0.0293352 |
| COG5 | component of oligomeric golgi complex 5 | -0.0291584 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0290226 |
| SBF2 | SET binding factor 2 | -0.0286752 |
| SEC24D | SEC24 family member D | -0.0281572 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0279824 |
| TNS4 | tensin 4 | -0.0276511 |
| SETD5 | SET domain containing 5 | -0.026939 |
| FAM13A | family with sequence similarity 13, member A | -0.0265041 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.026422 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0263009 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0262203 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0261358 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0260282 |
| KRT8 | keratin 8, type II | -0.0259794 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0255313 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0254903 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0253564 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0250105 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0247456 |
| CDK13 | cyclin-dependent kinase 13 | -0.0247057 |
| PHKB | phosphorylase kinase, beta | -0.0246423 |
| PARD3B | par-3 family cell polarity regulator beta | -0.024537 |
| CCDC91 | coiled-coil domain containing 91 | -0.0245364 |
| RTN4 | reticulon 4 | -0.0245226 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0244743 |
| FNIP1 | folliculin interacting protein 1 | -0.0240348 |
| RPL31 | ribosomal protein L31 | -0.024011 |
