| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT18 | keratin 18, type I | 0.0880592 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0725326 |
| MYO1E | myosin IE | 0.0575824 |
| ABHD17C | abhydrolase domain containing 17C | 0.0542541 |
| PKP2 | plakophilin 2 | 0.0537355 |
| RPS3 | ribosomal protein S3 | 0.0528724 |
| SERINC5 | serine incorporator 5 | 0.0460329 |
| PRSS3 | protease, serine, 3 | 0.0450267 |
| BCL2L1 | BCL2-like 1 | 0.0447499 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.043381 |
| TRIM2 | tripartite motif containing 2 | 0.0431676 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0422881 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0400714 |
| FAT1 | FAT atypical cadherin 1 | 0.0381673 |
| RPS4X | ribosomal protein S4, X-linked | 0.0372598 |
| RPS12 | ribosomal protein S12 | 0.0365157 |
| KLF6 | Kruppel-like factor 6 | 0.0361146 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0351767 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0351259 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0346469 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0344857 |
| EXT1 | exostosin glycosyltransferase 1 | 0.032423 |
| KIF5B | kinesin family member 5B | 0.0314415 |
| RPS8 | ribosomal protein S8 | 0.0301919 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | 0.0294184 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0293004 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0292045 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0288685 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0286559 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0286463 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0273508 |
| RPL37A | ribosomal protein L37a | 0.0263218 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0263188 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0262135 |
| RPL31 | ribosomal protein L31 | 0.0255545 |
| RPL12 | ribosomal protein L12 | 0.0254887 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0254872 |
| RACK1 | receptor for activated C kinase 1 | 0.0254632 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0248782 |
| TSPAN8 | tetraspanin 8 | 0.0247691 |
| LDHA | lactate dehydrogenase A | 0.0244674 |
| TXNRD1 | thioredoxin reductase 1 | 0.0244387 |
| CAB39 | calcium binding protein 39 | 0.0237455 |
| SQSTM1 | sequestosome 1 | 0.0237241 |
| ENO1 | enolase 1, (alpha) | 0.0235841 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0235016 |
| PCDHB16 | protocadherin beta 16 | 0.0233005 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0231666 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0227717 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0220993 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0220704 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0219288 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0218546 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0215136 |
| DUSP4 | dual specificity phosphatase 4 | 0.0214503 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0213731 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0212251 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0211346 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0209055 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0208433 |
| RPS29 | ribosomal protein S29 | 0.0208202 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0208175 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.020462 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0199918 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0199691 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0198945 |
| NOSTRIN | nitric oxide synthase trafficking | 0.019776 |
| S100P | S100 calcium binding protein P | 0.0193584 |
| SHROOM3 | shroom family member 3 | 0.0192755 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0192543 |
| TMEM45B | transmembrane protein 45B | 0.0192513 |
| TSPAN3 | tetraspanin 3 | 0.0190788 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0189777 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0188321 |
| CANX | calnexin | 0.0187257 |
| SRI | sorcin | 0.018666 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0183933 |
| EFNA1 | ephrin-A1 | 0.0182921 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0182667 |
| IL6ST | interleukin 6 signal transducer | 0.0181086 |
| ATP10B | ATPase, class V, type 10B | 0.0180622 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0179756 |
| RPL18 | ribosomal protein L18 | 0.0178352 |
| EREG | epiregulin | 0.0178252 |
| MX1 | MX dynamin-like GTPase 1 | 0.0177453 |
| FTL | ferritin, light polypeptide | 0.0175145 |
| RPS17 | ribosomal protein S17 | 0.0174921 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0174466 |
| GOLM1 | golgi membrane protein 1 | 0.0171356 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0171276 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0171038 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0168235 |
| GDA | guanine deaminase | 0.0167921 |
| COX6C | cytochrome c oxidase subunit VIc | 0.016783 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0166783 |
| NEK7 | NIMA-related kinase 7 | 0.0166465 |
| WWC1 | WW and C2 domain containing 1 | 0.0164121 |
| MT2A | metallothionein 2A | 0.0163187 |
| SNX6 | sorting nexin 6 | 0.0162557 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0161857 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.140111 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.112605 |
| ANXA2 | annexin A2 | -0.110534 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.105153 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.101565 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.10022 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0984106 |
| MSI2 | musashi RNA-binding protein 2 | -0.0981576 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0974641 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0864276 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0813977 |
| CALB1 | calbindin 1, 28kDa | -0.0780893 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0719946 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0705662 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0688939 |
| PCBP2 | poly(rC) binding protein 2 | -0.0663369 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0610671 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0606041 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0600106 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0573569 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0564163 |
| INTS6 | integrator complex subunit 6 | -0.0550146 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0536501 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0535046 |
| FHIT | fragile histidine triad | -0.0530067 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0519275 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0519171 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0516645 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0514936 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0505001 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0502601 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0499672 |
| FRMD5 | FERM domain containing 5 | -0.0498397 |
| ITGB4 | integrin, beta 4 | -0.049324 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0471048 |
| MCU | mitochondrial calcium uniporter | -0.046759 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0464499 |
| FNDC3B | fibronectin type III domain containing 3B | -0.046389 |
| SBF2 | SET binding factor 2 | -0.0462064 |
| PERP | PERP, TP53 apoptosis effector | -0.0457706 |
| NFIA | nuclear factor I/A | -0.0453041 |
| HMGA1 | high mobility group AT-hook 1 | -0.0447759 |
| ZNF638 | zinc finger protein 638 | -0.0446666 |
| NPSR1 | neuropeptide S receptor 1 | -0.0443784 |
| ACTG1 | actin gamma 1 | -0.0440848 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0440797 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0440727 |
| PKM | pyruvate kinase, muscle | -0.0438762 |
| LMO7 | LIM domain 7 | -0.0436248 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0428436 |
| RPS6 | ribosomal protein S6 | -0.042431 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0417872 |
| GOLGA4 | golgin A4 | -0.0416893 |
| AOPEP | aminopeptidase O (putative) | -0.0412991 |
| BRD2 | bromodomain containing 2 | -0.0411737 |
| NCOR2 | nuclear receptor corepressor 2 | -0.04114 |
| SETD5 | SET domain containing 5 | -0.0408562 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0406521 |
| RBM25 | RNA binding motif protein 25 | -0.0403327 |
| KRT8 | keratin 8, type II | -0.0402956 |
| TMSB10 | thymosin beta 10 | -0.0397054 |
| VMP1 | vacuole membrane protein 1 | -0.0396647 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0394815 |
| DENND1A | DENN/MADD domain containing 1A | -0.0392574 |
| ZNF609 | zinc finger protein 609 | -0.0389178 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.038801 |
| ARF4 | ADP-ribosylation factor 4 | -0.0384254 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0383977 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0383915 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0383032 |
| FOXO3 | forkhead box O3 | -0.0382991 |
| RREB1 | ras responsive element binding protein 1 | -0.0380364 |
| SVIL | supervillin | -0.0379637 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0375652 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.037335 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0361811 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.03581 |
| USP3 | ubiquitin specific peptidase 3 | -0.0356614 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0352958 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0350622 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0349428 |
| UBAP2 | ubiquitin associated protein 2 | -0.03492 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0346386 |
| GLG1 | golgi glycoprotein 1 | -0.034515 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0344589 |
| PTMA | prothymosin, alpha | -0.0344209 |
| POTEF | POTE ankyrin domain family, member F | -0.0343842 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0341312 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0339992 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0339781 |
| PRELID2 | PRELI domain containing 2 | -0.0339534 |
| TMEM165 | transmembrane protein 165 | -0.0338556 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0337236 |
| EXOC4 | exocyst complex component 4 | -0.0334462 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.033315 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0332316 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0327853 |
| ACTN4 | actinin, alpha 4 | -0.0326676 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0326131 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0326003 |