| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | (R)-Verapamil (hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the (R)-Verapamil (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.241811 |
| DST | dystonin | 0.170231 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.156764 |
| TP63 | tumor protein p63 | 0.096659 |
| HLA-B | major histocompatibility complex, class I, B | 0.0931209 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0874662 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0769675 |
| FMNL2 | formin-like 2 | 0.0719716 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0715174 |
| PRELID2 | PRELI domain containing 2 | 0.0714246 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0706898 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0690886 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.06855 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0678691 |
| RAD51B | RAD51 paralog B | 0.0633015 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0619979 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0613999 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0554252 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0541051 |
| RNF213 | ring finger protein 213 | 0.0507576 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0507284 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0499202 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0442367 |
| EZR | ezrin | 0.0436647 |
| MT1E | metallothionein 1E | 0.0433313 |
| B2M | beta-2-microglobulin | 0.0424143 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0412961 |
| SQSTM1 | sequestosome 1 | 0.0412177 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0412008 |
| SMYD3 | SET and MYND domain containing 3 | 0.0409529 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0409331 |
| RPS12 | ribosomal protein S12 | 0.0400965 |
| CAPRIN2 | caprin family member 2 | 0.0397164 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0375995 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0369396 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0363212 |
| SVIL | supervillin | 0.0362582 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0361698 |
| RTTN | rotatin | 0.0356699 |
| RUNX1 | runt-related transcription factor 1 | 0.0351139 |
| SPAG9 | sperm associated antigen 9 | 0.0347842 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0347063 |
| RPL36 | ribosomal protein L36 | 0.034338 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0332549 |
| VCL | vinculin | 0.0331884 |
| SYAP1 | synapse associated protein 1 | 0.0331372 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0325062 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0325037 |
| FERMT1 | fermitin family member 1 | 0.0322712 |
| HLA-A | major histocompatibility complex, class I, A | 0.0321462 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0319318 |
| PLK2 | polo-like kinase 2 | 0.0318654 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0318479 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0314383 |
| ACTN1 | actinin, alpha 1 | 0.031142 |
| SP100 | SP100 nuclear antigen | 0.0309823 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.030748 |
| CEP128 | centrosomal protein 128kDa | 0.0306631 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0301668 |
| SDC4 | syndecan 4 | 0.029918 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0294367 |
| PDE8A | phosphodiesterase 8A | 0.0294036 |
| KLF6 | Kruppel-like factor 6 | 0.0289884 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0288793 |
| TRIM56 | tripartite motif containing 56 | 0.0286599 |
| AREG | amphiregulin | 0.0286025 |
| ENO1 | enolase 1, (alpha) | 0.028467 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0281407 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0274698 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0274417 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0274358 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0271492 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0270832 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0270424 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0270085 |
| JAK1 | Janus kinase 1 | 0.0270079 |
| FUS | FUS RNA binding protein | 0.0269782 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0269082 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0268509 |
| THOC2 | THO complex 2 | 0.0267556 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0265253 |
| CDK6 | cyclin-dependent kinase 6 | 0.0260626 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0260013 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.025839 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0255683 |
| SLK | STE20-like kinase | 0.025514 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0254025 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0253819 |
| CSF3 | colony stimulating factor 3 (granulocyte) | 0.025298 |
| PRKCE | protein kinase C, epsilon | 0.0252023 |
| ASPH | aspartate beta-hydroxylase | 0.0250953 |
| BRCA1 | breast cancer 1, early onset | 0.0249748 |
| USP11 | ubiquitin specific peptidase 11 | 0.024846 |
| EREG | epiregulin | 0.024799 |
| PODXL | podocalyxin-like | 0.0247234 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0245986 |
| ANGPTL4 | angiopoietin-like 4 | 0.024248 |
| F2R | coagulation factor II (thrombin) receptor | 0.0241799 |
| TPR | translocated promoter region, nuclear basket protein | 0.0240732 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0238214 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.277915 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.174771 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.132442 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0936701 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0805753 |
| TXNRD1 | thioredoxin reductase 1 | -0.0804877 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.080329 |
| POTEF | POTE ankyrin domain family, member F | -0.0764289 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0741781 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.073079 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0713997 |
| CANX | calnexin | -0.0666161 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0620738 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0617386 |
| AHNAK | AHNAK nucleoprotein | -0.060595 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0559688 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0538007 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0525489 |
| EGR1 | early growth response 1 | -0.0516794 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0515012 |
| HMGA1 | high mobility group AT-hook 1 | -0.0507514 |
| ACTG1 | actin gamma 1 | -0.0496044 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0489746 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0401631 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0397809 |
| TMSB10 | thymosin beta 10 | -0.0393754 |
| RAI1 | retinoic acid induced 1 | -0.0371471 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0370327 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0356513 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0345354 |
| HDLBP | high density lipoprotein binding protein | -0.033668 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0329817 |
| DENND1A | DENN/MADD domain containing 1A | -0.0326054 |
| VIM | vimentin | -0.0319148 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0316415 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0315589 |
| MYOF | myoferlin | -0.0312967 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0306884 |
| EFNA5 | ephrin-A5 | -0.02818 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0280691 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0279534 |
| RPS6 | ribosomal protein S6 | -0.0273589 |
| RPLP0 | ribosomal protein, large, P0 | -0.0271499 |
| TAPBP | TAP binding protein (tapasin) | -0.0263842 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0262966 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0252954 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.025127 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0245302 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0245043 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.024316 |
| UPP1 | uridine phosphorylase 1 | -0.0242489 |
| EHBP1 | EH domain binding protein 1 | -0.023745 |
| ANXA1 | annexin A1 | -0.02346 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0233901 |
| RPL35A | ribosomal protein L35a | -0.0232306 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | -0.0230615 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0230502 |
| TMEM123 | transmembrane protein 123 | -0.0227625 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0226268 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0222404 |
| RASAL2 | RAS protein activator like 2 | -0.0218948 |
| WASF2 | WAS protein family, member 2 | -0.0217113 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0217007 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0215147 |
| BSG | basigin (Ok blood group) | -0.0213663 |
| OLA1 | Obg-like ATPase 1 | -0.0213589 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0211279 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0211137 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0208776 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0206452 |
| RPL4 | ribosomal protein L4 | -0.020137 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | -0.0197937 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0195535 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0195103 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0193998 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0193127 |
| TMSB4X | thymosin beta 4, X-linked | -0.0192225 |
| RHOA | ras homolog family member A | -0.0188725 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0188061 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0185738 |
| ZNF207 | zinc finger protein 207 | -0.0184131 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0183702 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0183318 |
| PGK1 | phosphoglycerate kinase 1 | -0.0182884 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0178796 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0176007 |
| NEK10 | NIMA-related kinase 10 | -0.0175843 |
| OSMR | oncostatin M receptor | -0.0175487 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0174624 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0173855 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0172728 |
| UBC | ubiquitin C | -0.0171898 |
| GOLGA4 | golgin A4 | -0.0170979 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0170559 |
| RPS16 | ribosomal protein S16 | -0.0169752 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0169562 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | -0.0168232 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | -0.0167716 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0167218 |
| ARF6 | ADP-ribosylation factor 6 | -0.0165754 |
